Search Results - "Vispé, S."

Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome by Vispé, S., Vandenberghe, I., Robin, M., Annereau, J.P., Créancier, L., Pique, V., Galy, J.P., Kruczynski, A., Barret, J.M., Bailly, C.

“…Acridine derivatives, such as amsacrine, represent a well known class of multi-targeted anti-cancer agents that generally interfere with DNA synthesis and…”
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A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment by Annereau, J.-P, Brel, V, Dumontet, C, Guminski, Y, Imbert, T, Broussas, M, Vispé, S, Bréand, S, Guilbaud, N, Barret, J.-M, Bailly, C

“…Abstract The polyamine transport system (PTS), hyperactive in cancer cells, can constitute a gate to deliver F14512, a novel spermine epipodophyllotoxin…”
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Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation by Vispé, Stéphane, Cazaux, Christophe, Lesca, Claire, Defais, Martine

“…Rad51 proteins share both structural and functional homologies with the bacterial recombinase RecA. The human Rad51 (HsRad51) is able to catalyse strand…”
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Characterization of the sensitivity to various genotoxic agents of the UVU1 CHO cell line, a double mutant from UV complementation group 1 by Lesca, C., Vispé, S., Defais, M.

“…The UVU1 CHO cell line, a double mutant of the excision repair complementation group 1 UV4 cell line was characterized by a higher UV sensitivity than its…”
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Mammalian Rad51 protein: A RecA homologue with pleitropic functions by Vispé, S., Defais, M.

“…During the last years, homologues of E coli RecA have been cloned in numerous species including man. These Rad51 proteins share sequence as well as functional…”
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Mammalian Rad51 protein: a RecA homologue with pleiotropic functions by Vispé, S, Defais, M

“…During the last years, homologues of E coli RecA have been cloned in numerous species including man. These Rad51 proteins share sequence as well as functional…”
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DNA repair patch-mediated double strand DNA break formation in human cells by Vispé, S, Satoh, M S

“…To investigate the mechanism of double strand DNA break formation in mammalian cells, an in vitro assay was established using closed circular DNA containing…”
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A Cellular Defense Pathway Regulating Transcription through Poly(ADP-ribosyl)ation in Response to DNA Damage by Vispe, S, Yung, T M, Ritchot, J, Serizawa, H, Satoh, M S

“…DNA damage is known to trigger key cellular defense pathways such as those involved in DNA repair. Here we provide evidence for a previously unrecognized…”
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DNA Repair Patch-mediated Double Strand DNA Break Formation in Human Cells by Vispe, S.

“…To investigate the mechanism of double strand DNA break formation in mammalian cells, an in vitro assay was established using closed circular DNA containing…”
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Double-strand DNA Break Formation Mediated by Flap Endonuclease-1 by Vispé, Stéphane, Ho, Erick L.Y., Yung, Tetsu M.C., Satoh, Masahiko S.

“…Double-strand DNA breaks are the most lethal type of DNA damage induced by ionizing radiations. Previously, we reported that double-strand DNA breaks can be…”
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Poly(ADP-ribose) Polymerase-1 Is a Negative Regulator of HIV-1 Transcription through Competitive Binding to TAR RNA with Tat times Positive Transcription Elongation Factor b (p-TEFb) Complex by Parent, M, Yung, TMC, Rancourt, A, Ho, ELY, Vispe, S, Suzuki-Matsuda, F, Uehara, A, Wada, T, Handa, H, Satoh, MS

“…Human immunodeficiency virus, type 1 (HIV-1) transcription is regulated by a virus-encoded protein, Tat, which forms a complex with a host cellular factor,…”
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