Search Results - "Viskupičová, Jana"

Simultaneously Determined Antioxidant and Pro-Oxidant Activity of Randomly Selected Plant Secondary Metabolites and Plant Extracts by Maliar, Tibor, Maliarová, Mária, Blažková, Marcela, Kunštek, Marek, Uváčková, Ľubica, Viskupičová, Jana, Purdešová, Andrea, Beňovič, Patrik

“…Oxidative stress is a well-known phenomenon arising from physiological and nonphysiological factors, defined by the balance between antioxidants and…”
Get full text

Antioxidant and Pro-Oxidant Properties of Selected Clinically Applied Antibiotics: Therapeutic Insights by Maliar, Tibor, Blažková, Marcela, Polák, Jaroslav, Maliarová, Mária, Ürgeová, Eva, Viskupičová, Jana

“…The balance between antioxidants and pro-oxidants plays a significant role in the context of oxidative stress, influenced by both physiological and…”
Get full text

The Adapted POM Analysis of Avenanthramides In Silico by Maliar, Tibor, Maliarová, Mária, Purdešová, Andrea, Jankech, Timotej, Gerhardtová, Ivana, Beňovič, Patrik, Dvořáček, Václav, Jágr, Michal, Viskupičová, Jana

“…POM analysis and related approaches are significant tools based on calculating various physico-chemical properties and predicting biological activity, ADME…”
Get full text

Antioxidant and Proteinase Inhibitory Activities of Selected Poppy (Papaver somniferum L.) Genotypes by Krošlák, Erik, Maliar, Tibor, Nemeček, Peter, Viskupičová, Jana, Maliarová, Mária, Havrlentová, Michaela, Kraic, Ján

“…Poppy seeds (Papaver somniferum L.) belong to tasty food ingredients however, they should be considered also as valuable source of biologically active…”
Get full text

Biologically valuable components, antioxidant activity and proteinase inhibition activity of leaf and callus extracts of Salvia sp by Vulganová, Katarína, Maliar, Tibor, Maliarová, Mária, Nemeček, Peter, Viskupičová, Jana, Balážová, Andrea, Sokol, Jozef

“…Sage is medicinal plant, known for its antioxidant and anti-inflammatory effects. Eight extract samples were tested in this study: extract from L. varieties…”
Get full text

Natural Polyphenols as SERCA Activators: Role in the Endoplasmic Reticulum Stress-Related Diseases by Viskupicova, Jana, Rezbarikova, Petronela

“…Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is a key protein responsible for transporting Ca2+ ions from the cytosol into the lumen of the…”
Get full text

Sarcoplasmic reticulum Ca2+-ATPase from rabbit skeletal muscle modified by peroxynitrite by Žižková, Petronela, Viskupičová, Jana, Blaškovič, Dušan, Štrosová, Miriam K, Žarkovič, Neven, Horáková, Lubica

“…Effect of peroxynitrite on SERCA1 activity was studied in correlation with enzyme carbonylation. Kinetic parameters and location of peroxynitrite effect on…”
Get more information

Lipophilic rutin derivatives for antioxidant protection of oil-based foods by Viskupicova, Jana, Danihelova, Martina, Ondrejovic, Miroslav, Liptaj, Tibor, Sturdik, Ernest

“…The lipase-catalysed synthesis of lipophilic flavonoid antioxidants via rutin acylation with fatty acids (C4–C18) in 2-methylbutan-2-ol was investigated…”
Get full text

Modulation of rabbit muscle sarcoplasmic reticulum Ca2+-ATPase activity by novel quercetin derivatives by Blaškovič, Dušan, Žižková, Petronela, Držík, Filip, Viskupičová, Jana, Veverka, Miroslav, Horáková, Ľubica

“…Abstract Sarcoplasmic reticulum Ca2+-ATPase (SERCA) is the pump crucial for calcium homeostasis and its impairment results in pathologies such as myopathy,…”
Get full text

Pycnogenol® and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca2+-ATPase by Žižková, Petronela, Viskupičová, Jana, Horáková, Ľubica

“…The effect of two natural standardized plant extracts, Pycnogenol® and EGb 761, on sarcoplasmic reticulum Ca2+-ATPase (SERCA) activity and posttranslational…”
Get full text

Natural and synthetic antioxidants: an updated overview by Augustyniak, Agnieszka, Bartosz, Grzegorz, Cipak, Ana, Duburs, Gunars, Horáková, L'ubica, Luczaj, Wojciech, Majekova, Magdalena, Odysseos, Andreani D, Rackova, Lucia, Skrzydlewska, Elzbieta, Stefek, Milan, Strosová, Miriam, Tirzitis, Gunars, Venskutonis, Petras Rimantas, Viskupicova, Jana, Vraka, Panagiota S, Zarković, Neven

“…Abstract The current understanding of the complex role of ROS in the organism and pathological sequelae of oxidative stress points to the necessity of…”
Get more information

Effect of high glucose concentrations on human erythrocytes in vitro by Viskupicova, Jana, Blaskovic, Dusan, Galiniak, Sabina, Soszyński, Mirosław, Bartosz, Grzegorz, Horakova, Lubica, Sadowska-Bartosz, Izabela

“…Exposure to high glucose concentrations in vitro is often employed as a model for understanding erythrocyte modifications in diabetes. However, effects of such…”
Get full text

Dysfunction of SERCA pumps as novel mechanism of methylglyoxal cytotoxicity by Zizkova, Petronela, Viskupicova, Jana, Heger, Vladimir, Rackova, Lucia, Majekova, Magdalena, Horakova, Lubica

“…Highlights •Interaction of methylglyoxal (MGX) with calcium pump (SERCA1) in cell free system.•Binding in the cytosolic region, conformational changes, drop of…”
Get full text

General toxicity assessment of the novel aldose reductase inhibitor cemtirestat by Prnová, Marta Šoltésová, Račková, Lucia, Kováčiková, Lucia, Balleková, Jana, Viskupičová, Jana, Micháliková, Silvia, Taşkoparan, Betul, Elmazoğlu, Zübeyir, Rižner, Tea Lanišnik, Karasu, Cimen, Banerjee, Sreeparna, Štefek, Milan

“…Cemtirestat, 3-mercapto-5 -[1,2,4]-triazino[5,6- ]indole-5-acetic acid was recently designed and patented as a highly selective and efficient aldose reductase…”
Get full text

Inhibitors of SARS-CoV-2 main protease: Biological efficacy and toxicity aspects by Viskupicova, Jana, Rezbarikova, Petronela, Kovacikova, Lucia, Kandarova, Helena, Majekova, Magdalena

“…The emergence of the highly contagious respiratory disease, COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a…”
Get full text

Modulation of rabbit muscle sarcoplasmic reticulum Ca(2+)-ATPase activity by novel quercetin derivatives by Blaškovič, Dušan, Zižková, Petronela, Držík, Filip, Viskupičová, Jana, Veverka, Miroslav, Horáková, Lubica

“…Sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) is the pump crucial for calcium homeostasis and its impairment results in pathologies such as myopathy, heart…”
Get full text

Rutin fatty acid esters: from synthesis to biological health effects and application by Viskupicova, Jana, Maliar, Tibor

“…Flavonoids are promising compounds with a significant therapeutic potential. However, rutin efficiency after oral administration is limited due to its poor…”
Get full text

Pycnogenol and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca-ATPase by Zižková, Petronela, Viskupičová, Jana, Horáková, L'ubica

“…The effect of two natural standardized plant extracts, Pycnogenol(®) and EGb 761, on sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) activity and…”
Get full text

Bioavailability and metabolism of flavonoids by Viskuplcova, J, Ondrejovic, M, Sturdik, E

“…Flavonoids are natural polyhydroxylated compounds with proved positive impact on human health. However, majority of the evidence relates to in vitro…”
Get full text

Pycnogenol Cytotoxicity in Pancreatic INS‐1E β cells Induced by Calcium Dysregulation by Viskupicova, Jana, Zizkova, Petronela, Rackova, Lucia, Horakova, Lubica

“…Natural standardized flavonoid extract from the bark of Pinus pinaster, Pycnogenol (Pyc), was recently found to decrease intensively the activity of…”
Get full text