Search Results - "Vishvakarma, Vicky"

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    Single Molecule Measurements of the Accessibility of Molecular Surfaces by Dey, Arpan, Vishvakarma, Vicky, Das, Anirban, Kallianpur, Mamata, Dey, Simli, Joseph, Roshni, Maiti, Sudipta

    Published in Frontiers in molecular biosciences (01-12-2021)
    “…An important measure of the conformation of protein molecules is the degree of surface exposure of its specific segments. However, this is hard to measure at…”
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    Journal Article
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    Serotonin Promotes Vesicular Association and Fusion by Modifying Lipid Bilayers by Saha Roy, Debsankar, Gupta, Ankur, Vishvakarma, Vicky, Krupa, Pawel, Li, Mai Suan, Maiti, Sudipta

    Published in The journal of physical chemistry. B (23-05-2024)
    “…The primary event in chemical neurotransmission involves the fusion of a membrane-limited vesicle at the plasma membrane and the subsequent release of its…”
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    Biophysical properties of the isolated spike protein binding helix of human ACE2 by Das, Anirban, Vishvakarma, Vicky, Dey, Arpan, Dey, Simli, Gupta, Ankur, Das, Mitradip, Vishwakarma, Krishna Kant, Roy, Debsankar Saha, Yadav, Swati, Kesarwani, Shubham, Venkatramani, Ravindra, Maiti, Sudipta

    Published in Biophysical journal (20-07-2021)
    “…The entry of the severe acute respiratory syndrome coronavirus 2 virus in human cells is mediated by the binding of its surface spike protein to the human…”
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    Rational Design of Protein-Specific Folding Modifiers by Das, Anirban, Yadav, Anju, Gupta, Mona, R, Purushotham, Terse, Vishram L, Vishvakarma, Vicky, Singh, Sameer, Nandi, Tathagata, Banerjee, Arkadeep, Mandal, Kalyaneswar, Gosavi, Shachi, Das, Ranabir, Ainavarapu, Sri Rama Koti, Maiti, Sudipta

    Published in Journal of the American Chemical Society (10-11-2021)
    “…Protein-folding can go wrong in vivo and in vitro, with significant consequences for the living organism and the pharmaceutical industry, respectively. Here we…”
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  10. 10

    Spontaneous Fluctuations Can Guide Drug Design Strategies for Structurally Disordered Proteins by Maity, Barun Kumar, Vishvakarma, Vicky, Surendran, Dayana, Rawat, Anoop, Das, Anirban, Pramanik, Shreya, Arfin, Najmul, Maiti, Sudipta

    Published in Biochemistry (Easton) (17-07-2018)
    “…Structure-based “rational” drug design strategies fail for diseases associated with intrinsically disordered proteins (IDPs). However, structural disorder…”
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    A Toxicogenic Interaction between Intracellular Amyloid‑β and Apolipoprotein‑E by Dey, Arpan, Verma, Aditi, Bhaskar, Uchit, Sarkar, Bidyut, Kallianpur, Mamata, Vishvakarma, Vicky, Das, Anand Kant, Garai, Kanchan, Mukherjee, Odity, Ishii, Kunihiko, Tahara, Tahei, Maiti, Sudipta

    Published in ACS chemical neuroscience (20-03-2024)
    “…Alzheimer’s disease (AD) is associated with the aggregation of amyloid β (Aβ) and tau proteins. Why ApoE variants are significant genetic risk factors remains…”
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    Journal Article