Search Results - "Vishnuvardhan, D"

Pin density technique for congestion estimation and reduction of optimized design during placement and routing by Karimullah, Shaik, Vishnuvardhan, D.

“…This work presents an estimation of design parameters for placement and routing in IC fabrication with the help of the existing Floorplan, done using the…”
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An Improved Harmony Search Approach for Block Placement for VLSI Design Automation by Karimullah, Shaik, Vishnuvardhan, D., Bhaskar, Vidhyacharan

“…Level of knowledge with the field for VLSI IC Design’s Placement and Routing and in the area of Wireless Communication is rapidly evolving; Hence the process…”
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Genetic inactivation of prohormone convertase (PC1) causes a reduction in cholecystokinin (CCK) levels in the hippocampus, amygdala, pons and medulla in mouse brain that correlates with the degree of colocalization of PC1 and CCK mRNA in these structures in rat brain by Cain, B. M., Connolly, K., Blum, A. C., Vishnuvardhan, D., Marchand, J. E., Zhu, X., Steiner, D. F., Beinfeld, M. C.

“…Prohormone convertase (PC1) is found in endocrine cell lines that express cholecystokinin (CCK) mRNA and process pro CCK to biologically active products. Other…”
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Role of Tyrosine Sulfation and Serine Phosphorylation in the Processing of Procholecystokinin to Amidated Cholecystokinin and Its Secretion in Transfected AtT-20 Cells by Vishnuvardhan, Daesety, Beinfeld, Margery C

“…Mammalian procholecystokinin (pro-CCK) is known to have three sulfated tyrosine residues, one of which is present in the CCK 8 moiety and two additional…”
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Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin by Hesse, Leah M., Sakai, Yumiko, Vishnuvardhan, Daesety, Li, Albert P., von Moltke, Lisa L., Greenblatt, David J.

“…ABSTRACT Animals treated with multiple doses of bupropion have had increased bupropion clearance or increased liver weight, suggesting induction of…”
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Expression of highly active recombinant NS3 protease domain of hepatitis C virus in E. coli by Vishnuvardhan, Daesety, Kakiuchi, Nobuko, Urvil, Petri T, Shimotohno, Kunitada, Kumar, P.K.R, Nishikawa, Satoshi

“…The serine protease domain of HCV comprising amino acids 1027–1218 (ΔNS3) was expressed in E. coli with a His tag at its N-terminal end. The protease was…”
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Unusual Biphasic Melting Behavior of Rhodotorula gracilis DNA by Vishnuvardhan, D., Divakar, S., Joseph, R.

“…Ultraviolet, fluorescence and CD spectral analysis suggested unusual structural features of Rhodotorula gracilis ATCC 90950 DNA. R. gracilis DNA exhibited 13%…”
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simple method for isolation of high-molecular-weight DNA from Rhodotorula gracilis by Vishnuvardhan, D, Joseph, R

“…Unsheared DNA has been isolated from Rhodotorula and Rhodosporidium yeasts using a cell-wall-digesting enzyme preparation from Paecilomyces lilacinus…”
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Interaction of Co, Mn, Mg and Al with d(GCGTACGC): a spectroscopic study by Rajan, M T, Kumar, D C, Vishnuvardhan, D, Rao, K S, Viswamitra, M A

“…Spectroscopic study on the interactions of trace elements Co., Mn, Mg and Al with d(GCGTACGC) indicated the following: Al and Mg did not alter Tm values. Mn…”
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Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein by VISHNUVARDHAN, Daesety, VON MOLTKE, Lisa L, RICHERT, Clemens, GREENBLATT, David J

“…The effect of lopinavir on P-glycoprotein-mediated rhodamine 123 efflux was studied in Caco-2 monolayer cells. Lopinavir is a potent inhibitor of Rh123 efflux…”
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Obliteration of α‐melanocyte‐stimulating hormone derived from POMC in pituitary and brains of PC2‐deficient mice by Miller, Ruthellen, Aaron, Wade, Toneff, Thomas, Vishnuvardhan, Daesety, Beinfeld, Margery C., Hook, Vivian Y. H.

“…Alpha‐melanocyte‐stimulating hormone (α‐MSH) is a neuropeptide expressed in pituitary and brain that is known to regulate energy balance, appetite control, and…”
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Cholecystokinin Levels in Prohormone Convertase 2 Knock-out Mouse Brain Regions Reveal a Complex Phenotype of Region-specific Alterations by Beinfeld, Margery C., Blum, Alissa, Vishnuvardhan, Daesety, Fanous, Sanya, Marchand, James E.

“…Prohormone convertase 2 is widely co-localized with cholecystokinin in rodent brain. To examine its role in cholecystokinin processing, cholecystokinin levels…”
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INTERACTION OF TRIAZOLAM AND KETOCONAZOLE IN P-GLYCOPROTEIN-DEFICIENT MICE by VON MOLTKE, Lisa L, GRANDA, Brian W, GRASSI, Jeffrey M, PERLOFF, Michael D, VISHNUVARDHAN, Daesety, GREENBLATT, David J

“…The role of P-glycoprotein (P-gp) on the distribution of the benzodiazepine triazolam (TRZ) and the azole antifungal agent ketoconazole (KET), and on the…”
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Isolation of RNA Aptamers Specific to the NS3 Protein of Hepatitis C Virus from a Pool of Completely Random RNA by Kumar, P.K.R., Machida, Keigo, Urvil, Petri T., Kakiuchi, Nobuko, Vishnuvardhan, Daesety, Shimotohno, Kunitada, Taira, Kazunari, Nishikawa, Satoshi

“…Hepatitis C virus (HCV) is a single-stranded RNA virus and its genome is translated into a single large polyprotein. The viral-encoded NS3 protein possesses…”
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Biosynthesis and Post-Translational Processing of Site-Directed Endoproteolytic Cleavage Mutants of Pro-CCK in AtT-20 Cells by Vishnuvardhan, Daesety, Beinfeld, Margery C

“…Site-directed mutagenesis in which individual cleavage site P1 amino acids were changed to Ala was performed to delineate their importance in the processing of…”
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Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice by Miller, Ruthellen, Toneff, Thomas, Vishnuvardhan, Daesety, Beinfeld, Margery, Hook, Vivian Y.H.

“…The prohormone convertase 2 (PC2) is hypothesized to convert multiple pro-neuropeptides into active peptides that function as neurotransmitters. To examine the…”
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Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein by Vishnuvardhan, D, von Moltke, LL, Richert, C, Greenblatt, D J

“…The effect of lopinavir on P-glycoprotein-mediated rhodamine 123 efflux was studied in Caco-2 monolayer cells. Lopinavir is a potent inhibitor of Rh123 efflux…”
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PC2 and 7B2 Null Mice Demonstrate That PC2 Is Essential for Normal Pro-CCK Processing by Vishnuvardhan, Daesety, Connolly, Kelly, Cain, Brian, Beinfeld, Margery C.

“…Analysis of CCK content in extracts of whole forebrain from PC2 and 7B2 null mouse brain showed a significant decrease relative to wild-type brains. More…”
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Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22 by Cain, Brian M., Vishnuvardhan, Daesety, Beinfeld, Margery C.

“…Endocrine tumor cells in culture and in vitro cleavage assays have shown that PC1 and PC2 are capable of processing pro-CCK into smaller, intermediate and…”
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Cleavage-Site Mutagenesis Alters Post-translation Processing of Pro-CCK in AtT-20 Cells by Pratt, John S, Blum, Alissa, Vishnuvardhan, Daesety, Kitagawa, Kouki, Beinfeld, Margery C

“…Cholecystokinin (CCK) is expressed in the central and peripheral nervous systems and functions as a neurotransmitter and neuroendocrine hormone. The in vivo…”
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