Search Results - "Visani, Giuseppe"

BCR-ABL Independent Mechanisms of Resistance in Chronic Myeloid Leukemia by Loscocco, Federica, Visani, Giuseppe, Galimberti, Sara, Curti, Antonio, Isidori, Alessandro

“…Not all chronic myeloid leukemia (CML) patients are cured with tyrosine kinase inhibitors (TKIs), and a proportion of them develop resistance. Recently,…”
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Vemurafenib plus Rituximab in Refractory or Relapsed Hairy-Cell Leukemia by Tiacci, Enrico, De Carolis, Luca, Simonetti, Edoardo, Capponi, Monia, Ambrosetti, Achille, Lucia, Eugenio, Antolino, Agostino, Pulsoni, Alessandro, Ferrari, Samantha, Zinzani, Pier L, Ascani, Stefano, Perriello, Vincenzo M, Rigacci, Luigi, Gaidano, Gianluca, Della Seta, Roberta, Frattarelli, Natalia, Falcucci, Paolo, Foà, Robin, Visani, Giuseppe, Zaja, Francesco, Falini, Brunangelo

“…The rare indolent B-cell cancer hairy-cell leukemia is often driven by activating BRAF mutations. BRAF inhibition induces responses, but relapse is common when…”
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Immunological Response Against SARS-COV-2 After BNT162b2 Vaccine Administration Is Impaired in Allogeneic but Not in Autologous Stem Cell Transplant Recipients by Chiarucci, Martina, Paolasini, Sara, Isidori, Alessandro, Guiducci, Barbara, Loscocco, Federica, Capalbo, Maria, Visani, Giuseppe

“…The efficacy of Covid-19 vaccine in hematopoietic stem cell transplantation (HSCT) recipients is still unknown. We planned a prospective study to evaluate the…”
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Immunotherapy in Acute Myeloid Leukemia: Where We Stand by Isidori, Alessandro, Cerchione, Claudio, Daver, Naval, DiNardo, Courtney, Garcia-Manero, Guillermo, Konopleva, Marina, Jabbour, Elias, Ravandi, Farhad, Kadia, Tapan, Burguera, Adolfo de la Fuente, Romano, Alessandra, Loscocco, Federica, Visani, Giuseppe, Martinelli, Giovanni, Kantarjian, Hagop, Curti, Antonio

“…In the past few years, our improved knowledge of acute myeloid leukemia (AML) pathogenesis has led to the accelerated discovery of new drugs and the…”
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Treatment options for acute myeloid leukemia patients aged <60 years by Visani, Giuseppe, Chiarucci, Martina, Paolasini, Sara, Loscocco, Federica, Isidori, Alessandro

“…Treatment of acute myeloid leukemia (AML) has changed over the last few years, after the discovery of new drugs selectively targeting AML blasts. Although 3/7…”
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SARS-CoV-2 impact in a community-based hematological ward in an Italian Red Zone by Visani, Giuseppe, Chiarucci, Martina, Guiducci, Barbara, Capalbo, Maria, Isidori, Alessandro

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The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia by Ciciarello, Marilena, Corradi, Giulia, Loscocco, Federica, Visani, Giuseppe, Monaco, Federica, Cavo, Michele, Curti, Antonio, Isidori, Alessandro

“…Mesenchymal stromal cells (MSCs) have, for a long time, been recognized as pivotal contributors in the set up and maintenance of the hematopoietic stem cell…”
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Antigen Receptors Gene Analysis for Minimal Residual Disease Detection in Acute Lymphoblastic Leukemia: The Role of High Throughput Sequencing by Piccaluga, Pier Paolo, Paolini, Stefania, Visani, Giuseppe

“…The prognosis of adult acute lymphoblastic leukemia (ALL) is variable but more often dismal. Indeed, its clinical management is challenging, current therapies…”
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XRCC1 399GG genotype predicts significantly longer overall survival in resistant lymphoma patients treated with Benda-EAM and ASCT by Visani, Giuseppe, Loscocco, Federica, Bagaloni, Irene, Ruzzo, Annamaria, Fuligni, Fabio, Graziano, Francesco, Magnani, Mauro, Isidori, Alessandro

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Chemotherapy-Induced Tumor Cell Death at the Crossroads Between Immunogenicity and Immunotolerance: Focus on Acute Myeloid Leukemia by Ocadlikova, Darina, Lecciso, Mariangela, Isidori, Alessandro, Loscocco, Federica, Visani, Giuseppe, Amadori, Sergio, Cavo, Michele, Curti, Antonio

“…In solid tumors and hematological malignancies, including acute myeloid leukemia, some chemotherapeutic agents, such as anthracyclines, have proven to activate…”
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Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling by Tripodo, Claudio, Burocchi, Alessia, Piccaluga, Pier Paolo, Chiodoni, Claudia, Portararo, Paola, Cappetti, Barbara, Botti, Laura, Gulino, Alessandro, Isidori, Alessandro, Liso, Arcangelo, Visani, Giuseppe, Martelli, Maria Paola, Falini, Brunangelo, Pandolfi, Pier Paolo, Colombo, Mario P, Sangaletti, Sabina

“…Systemic immune stimulation has been associated with increased risk of myeloid malignancies, but the pathogenic link is unknown. We demonstrate in animal…”
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BeEAM (bendamustine, etoposide, cytarabine, melphalan) before autologous stem cell transplantation is safe and effective for resistant/relapsed lymphoma patients by Visani, Giuseppe, Malerba, Lara, Stefani, Pietro Maria, Capria, Saveria, Galieni, Piero, Gaudio, Francesco, Specchia, Giorgina, Meloni, Giovanna, Gherlinzoni, Filippo, Giardini, Claudio, Falcioni, Sadia, Cuberli, Francesca, Gobbi, Marco, Sarina, Barbara, Santoro, Armando, Ferrara, Felicetto, Rocchi, Marco, Ocio, Enrique M., Caballero, Maria Dolores, Isidori, Alessandro

“…We designed a phase 1-2 study to evaluate the safety and the efficacy of increasing doses of bendamustine (160 mg/m2, 180 mg/m2, and 200 mg/m2 given on days −7…”
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Hematopoietic and leukemic stem cells homeostasis: the role of bone marrow niche by Khattab, Shaimaa, El Sorady, Manal, El-Ghandour, Ashraf, Visani, Giuseppe, Piccaluga, Pier Paolo

“…The bone marrow microenvironment (BMM) has highly specialized anatomical characteristics that provide a sanctuary place for hematopoietic stem cells (HSCs)…”
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Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid Leukemia Patients Treated With Nilotinib by Loscocco, Federica, Visani, Giuseppe, Ruzzo, Annamaria, Bagaloni, Irene, Fuligni, Fabio, Galimberti, Sara, Di Paolo, Antonello, Stagno, Fabio, Pregno, Patrizia, Annunziata, Mario, Gozzini, Antonella, Barulli, Sara, Gabucci, Elisa, Magnani, Mauro, Isidori, Alessandro

“…Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of…”
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Molecular Profiling of Kenyan Acute Myeloid Leukemia Patients by Gatua, Mercy, Navari, Mohsen, Ong’ondi, Matilda, Onyango, Noel, Kaggia, Serah, Rogena, Emily, Visani, Giuseppe, Abinya, Nicholas A., Piccaluga, Pier Paolo

“…Acute myeloid leukemia (AML) is an infrequent disease, and it is associated with high morbidity and mortality. It harbors a unique configuration of cytogenetic…”
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Metabolic Switch and Cytotoxic Effect of Metformin on Burkitt Lymphoma by Bagaloni, Irene, Visani, Axel, Biagiotti, Sara, Ruzzo, Annamaria, Navari, Mohsen, Etebari, Maryam, Mundo, Lucia, Granai, Massimo, Lazzi, Stefano, Isidori, Alessandro, Loscocco, Federica, Li, Jiejin, Leoncini, Lorenzo, Visani, Giuseppe, Magnani, Mauro, Piccaluga, Pier Paolo

“…Altered cellular energetic metabolism has recently emerged as important feature of neoplastic cells. Indeed, interfering with cancer cell metabolism might…”
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Surface antigens analysis reveals significant expression of candidate targets for immunotherapy in adult acute lymphoid leukemia by Piccaluga, Pier Paolo, Arpinati, Mario, Candoni, Anna, Laterza, Claudio, Paolini, Stefania, Gazzola, Anna, Sabattini, Elena, Visani, Giuseppe, Pileri, Stefano A.

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PB2379: SPECIFIC ALTERATIONS IN MEMBRANE LIPID LEVELS AS POTENTIAL BIOMARKERS IN DLBCL PATIENTS by Loscocco, Federica, DI Nolfo, Federica, Isidori, Alessandro, Sansone, Anna, Brunori, Marino, Chiarucci, Martina, Calandrelli, Monica, Visani, Giuseppe, Ferreri, Carla

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Effects of iron overload and hepatitis C virus positivity in determining progression of liver fibrosis in thalassemia following bone marrow transplantation by Angelucci, Emanuele, Muretto, Pietro, Nicolucci, Antonio, Baronciani, Donatella, Erer, Buket, Gaziev, Javid, Ripalti, Marta, Sodani, Pietro, Tomassoni, Silvia, Visani, Giuseppe, Lucarelli, Guido

“…To identify the role of iron overload in the natural history of liver fibrosis, we reviewed serial hepatic biopsy specimens taken annually from patients cured…”
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Thiotepa‐busulfan‐fludarabine Compared to Treosulfan‐based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT by Saraceni, Francesco, Labopin, Myriam, Raiola, Anna M., Blaise, Didier, Reményi, Péter, Sorà, Federica, Pavlu, Jiri, Bramanti, Stefania, Busca, Alessandro, Berceanu, Ana, Battipaglia, Giorgia, Visani, Giuseppe, Sociè, Gerard, Bug, Gesine, Micò, Caterina, La Nasa, Giorgio, Musso, Maurizio, Olivieri, Attilio, Spyridonidis, Alexandros, Savani, Bipin, Ciceri, Fabio, Nagler, Arnon, Mohty, Mohamad

“…We conducted a registry analysis including adult acute myeloid leukemia (AML) patients in remission who had received thiotepa, busulfan, and fludarabine (TBF)…”
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