Search Results - "Virtanen, T"
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Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-02-2019)“…Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers and Activators of Transcription) pathway, play a central role in the…”
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Development of antioxidant activity in milk whey during fermentation with lactic acid bacteria
Published in Journal of applied microbiology (2007)“…To investigate the production of antioxidant activity during fermentation with commonly used dairy starter cultures. Moreover, to study the development of…”
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Understanding the cross-linking reactions in highly oxidized graphene/epoxy nanocomposite systems
Published in Journal of materials science (01-02-2019)“…Graphene oxide (GO) was produced using acidic graphite oxidation and dispersed within an epoxy matrix using a solvent-based technique, to give nanocomposites…”
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Student Engagement and School Burnout in Finnish Lower-Secondary Schools: Latent Profile Analysis
Published in Scandinavian journal of educational research (04-07-2018)“…Self-ratings of behavioural engagement, cognitive engagement and school burnout were used in person-centred analyses to identify latent profiles among 2,485…”
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Structural Features of Hydrolyzable Tannins Determine Their Ability to Form Insoluble Complexes with Bovine Serum Albumin
Published in Journal of agricultural and food chemistry (19-06-2019)“…The ability of 32 purified and characterized hydrolyzable tannins to form insoluble complexes with model protein bovine serum albumin was investigated with a…”
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A Validation Study of Classroom Assessment Scoring System–Secondary in the Finnish School Context
Published in The Journal of early adolescence (01-06-2018)“…This study examined the reliability and validity of the Classroom Assessment Scoring System–Secondary (CLASS-S) in Finnish classrooms. Trained observers coded…”
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Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2023)“…Hyperactive mutation V617F in the JAK2 regulatory pseudokinase domain (JH2) is prevalent in patients with myeloproliferative neoplasms. Here, we identified…”
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The Role of Perceived Social Support as a Contributor to the Successful Transition from Primary to Lower Secondary School
Published in Scandinavian journal of educational research (09-11-2020)“…Following approximately 1,800 Finnish children, this longitudinal study examined the associations between students' perceived social support (teacher-student…”
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Methane dynamics in the subarctic tundra: combining stable isotope analyses, plot- and ecosystem-scale flux measurements
Published in Biogeosciences (02-02-2016)“…Methane (CH4) fluxes were investigated in a subarctic Russian tundra site in a multi-approach study combining plot-scale data, ecosystem-scale eddy covariance…”
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Carbon dioxide balance of subarctic tundra from plot to regional scales
Published in Biogeosciences (24-01-2013)“…We report here the carbon dioxide (CO2) budget of a 98.6 km2 subarctic tundra area in northeast European Russia based on measurements at two different scales…”
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Mammalian lipocalin allergens - insights into their enigmatic allergenicity
Published in Clinical and experimental allergy (01-04-2012)“…Summary Most of the important mammal‐derived respiratory allergens, as well as a milk allergen and a few insect allergens, belong to the lipocalin protein…”
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Analyzing Measurement Invariance of the Students’ Engagement Instrument Brief Version: The Cases of Denmark, Finland, and Portugal
Published in Canadian journal of school psychology (01-12-2018)“…The promotion of students’ engagement with school is an internationally acknowledged challenge in education. There is a need to examine the structure of the…”
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Hyperactivation of Oncogenic JAK3 Mutants Depend on ATP Binding to the Pseudokinase Domain
Published in Frontiers in oncology (03-12-2018)“…Janus kinase 3 (JAK3) tyrosine kinase has a central role in the control of lymphopoiesis, and mutations in JAK3 can lead to either severe combined…”
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Psoriasin and its allergenic bovine homolog Bos d 3
Published in Cellular and molecular life sciences : CMLS (01-05-2006)“…Since allergic diseases are a widespread health problem in the industrialized countries, clarifying the mechanism of allergy is a necessary objective for…”
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Determination of land surface reflectance using the AATSR dual-view capability
Published in Atmospheric measurement techniques (22-02-2015)“…In this study, a method is presented to retrieve the surface reflectance using the radiances measured at the top of the atmosphere for the two views provided…”
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Indirect estimation of absorption properties for fine aerosol particles using AATSR observations: a case study of wildfires in Russia in 2010
Published in Atmospheric measurement techniques (03-08-2015)“…The Advanced Along-Track Scanning Radiometer (AATSR) on board the ENVISAT satellite is used to study aerosol properties. The retrieval of aerosol properties…”
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Animal-derived lipocalin allergens exhibit immunoglobulin E cross-reactivity
Published in Clinical and experimental allergy (01-02-2008)“…Summary Background Although knowledge of the IgE cross‐reactivity between allergens is important for understanding the mechanisms of allergy, the regulation of…”
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The regulation of JAKs in cytokine signaling and its breakdown in disease
Published in Cytokine (Philadelphia, Pa.) (01-06-2019)“…•Janus kinases (JAK1–3, TYK2) mediate signal transduction of over 50 cytokines.•JAK–STAT signaling is tightly regulated on multiple levels.•Over 150…”
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Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein
Published in Clinical and experimental allergy (01-05-2016)“…Summary Background Human CD4+ T cell responses to important animal allergens are still insufficiently understood. Objective To comprehensively characterize…”
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