Search Results - "Virta, R."

Amyloid PET imaging in patients with mild cognitive impairment: A 2-year follow-up study by KOIVUNEN, J, SCHEININ, N, VIRTA, J. R, AALTO, S, VAHLBERG, T, NAGREN, K, HELIN, S, PARKKOLA, R, VIITANEN, M, RINNE, J. O

“…Patients with amnestic mild cognitive impairment (MCI) have greater risk of conversion to Alzheimer disease (AD). Increased brain amyloid burden in AD and MCI…”
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Adenosine A2A Receptors in Secondary Progressive Multiple Sclerosis: A [11C]TMSX Brain PET Study by Rissanen, Eero, Virta, Jere R, Paavilainen, Teemu, Tuisku, Jouni, Helin, Semi, Luoto, Pauliina, Parkkola, Riitta, Rinne, Juha O, Airas, Laura

“…In this study, positron emission tomography (PET) imaging with a radioligand to adenosine A2A receptors (A2AR)—a potent regulator of inflammation—was used to…”
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Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures by Kähkönen, T. E., Toriseva, M., Petruk, N., Virta, A.-R., Maher, A., Eigéliené, N., Kaivola, J., Boström, P., Koskivuo, I., Nees, M., Tuomela, J. M., Ivaska, K. K., Härkönen, P. L.

“…Purpose Fibroblast growth factor receptors (FGFR) and pathways are important players in breast cancer (BC) development. They are commonly altered, and BCs…”
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[11C]PIB, [18F]FDG and MR imaging in patients with mild cognitive impairment by Brück, A., Virta, J. R., Koivunen, J., Koikkalainen, J., Scheinin, N. M., Helenius, H., Någren, K., Helin, S., Parkkola, R., Viitanen, M., Rinne, J. O.

“…Purpose Cortical glucose metabolism, brain amyloid β accumulation and hippocampal atrophy imaging have all been suggested as potential biomarkers in predicting…”
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Cholinergic activity correlates with reserve proxies in Alzheimer's disease by Garibotto, Valentina, Tettamanti, Marco, Marcone, Alessandra, Florea, Ioana, Panzacchi, Andrea, Moresco, Rosamaria, Virta, Jere R, Rinne, Juha, Cappa, Stefano F, Perani, Daniela

“…Abstract The clinical expression of Alzheimer's disease (AD) occurs as neuropathology exceeds the brain “reserve capacity.” A possible association between the…”
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[11C]-MP4A PET cholinergic measurements in amnestic mild cognitive impairment, probable Alzheimer's disease, and dementia with Lewy bodies: a Bayesian method and voxel-based analysis by Marcone, Alessandra, Garibotto, Valentina, Moresco, Rosa Maria, Florea, Ioana, Panzacchi, Andrea, Carpinelli, Assunta, Virta, Jere R, Tettamanti, Marco, Borroni, Barbara, Padovani, Alessandro, Bertoldo, Alessandra, Herholz, Karl, Rinne, Juha O, Cappa, Stefano Francesco, Perani, Daniela

“…Non-invasive approaches for positron emission tomography (PET) parametric imaging of acetylcholinesterase (AChE) activity have been developed and applied to…”
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Test-retest reliability of (11)C-ORM-13070 in PET imaging of α2C-adrenoceptors in vivo in the human brain by Lehto, Jussi, Virta, Jere R, Oikonen, Vesa, Roivainen, Anne, Luoto, Pauliina, Arponen, Eveliina, Helin, Semi, Hietamäki, Johanna, Holopainen, Aila, Kailajärvi, Marita, Peltonen, Juha M, Rouru, Juha, Sallinen, Jukka, Virtanen, Kirsi, Volanen, Iina, Scheinin, Mika, Rinne, Juha O

“…α2C-Adrenoceptors share inhibitory presynaptic functions with the more abundant α2A-adrenoceptor subtype, but they also have widespread postsynaptic modulatory…”
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Cerebral acetylcholinesterase activity is not decreased in MS patients with cognitive impairment by Virta, Jere R, Laatu, Sari, Parkkola, Riitta, Oikonen, Vesa, Rinne, Juha O, Ruutiainen, Juhani

“…Background: Neuropsychological studies have extensively described the presence of cognitive dysfunction in MS patients. One possible pharmacological treatment…”
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Intriguing electrochemistry in low-temperature single layer ceramic fuel cells based on CuFe2O4 by Asghar, M.I., Yao, X., Jouttijärvi, S., Hochreiner, E., Virta, R., Lund, P.D.

“…A composite of CuFe2O4 and Gd-Sm co-doped CeO2 is studied for a single layer ceramic fuel cell application. In order to optimize the cell performance, the…”
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Role of insulin and hyperglycemia in the modulation of osteocalcin secretion in osteoblasts by Ivaska, K.K, Virta, A.-R, Halme, L, Heino, T, Väänänen, H.K

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Cerebral oxygen and glucose metabolism in patients with mitochondrial m.3243A>G mutation by Lindroos, Markus M., Borra, Ronald J., Parkkola, Riitta, Virtanen, Sami M., Lepomäki, Virva, Bucci, Marco, Virta, Jere R., Rinne, Juha O., Nuutila, Pirjo, Majamaa, Kari

“…The m.3243A>G mutation is the most common pathogenic mutation in mitochondrial DNA. It leads to defective oxidative phosphorylation, decreased oxygen…”
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1-11C-Methyl-4-Piperidinyl-N-Butyrate Radiation Dosimetry in Humans by Dynamic Organ-Specific Evaluation by Virta, Jere R, Tolvanen, Tuula, Nagren, Kjell, Bruck, Anna, Roivainen, Anne, Rinne, Juha O

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P2-093: The effects of the E4 allele of apolipoprotein E and the K variant of butyrylcholinesterase on cerebral butyrylcholinesterase activity in patients with Alzheimer's disease by Virta, Jere R, Någren, Kjell, Jarvenpaa, Tarja, Roivainen, Anne, Oikonen, Vesa, Mononen, Nina, Mattila, Kari M, Lehtimaki, Terho, Kurki, Timo, Rinne, Juha O

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Characterization of mineral population by index particle: implication for the Stanton hypothesis by Wylie, A G, Virta, R L, Segreti, J M

“…Fibers from seven crocidolite samples used by M. F. Stanton et al. (J. Natl. Cancer Inst. 67, 965-975 (1981] were measured from STEM and optical images. Their…”
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A model for predicting crocidolite fiber size distributions by Virta, R L, Segreti, J M

“…To minimize the problems of sample mass inconsistency associated with limited fiber counts, a model has been developed to predict the particle size…”
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Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated mineral particulates by comparison with a STEM technique by Snyder, J G, Virta, R L, Segreti, J M

“…The USPHS/NIOSH Membrane Filter Method is used to monitor for asbestos in occupational and mining atmospheres, and employs the phase-contrast optical…”
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Test-retest reliability of super(11)C-ORM-13070 in PET imaging of alpha sub(2C)-adrenoceptors in vivo in the human brain by Lehto, Jussi, Virta, Jere R, Oikonen, Vesa, Roivainen, Anne, Luoto, Pauliina, Arponen, Eveliina, Helin, Semi, Hietamaeki, Johanna, Holopainen, Aila, Kailajaervi, Marita, Peltonen, Juha M, Rouru, Juha, Sallinen, Jukka, Virtanen, Kirsi, Volanen, Iina, Scheinin, Mika, Rinne, Juha O

“…Purpose: alpha sub(2C)-Adrenoceptors share inhibitory presynaptic functions with the more abundant alpha sub(2A)-adrenoceptor subtype, but they also have…”
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Test–retest reliability of 11C-ORM-13070 in PET imaging of α2C-adrenoceptors in vivo in the human brain by Lehto, Jussi, Virta, Jere R., Oikonen, Vesa, Roivainen, Anne, Luoto, Pauliina, Arponen, Eveliina, Helin, Semi, Hietamäki, Johanna, Holopainen, Aila, Kailajärvi, Marita, Peltonen, Juha M., Rouru, Juha, Sallinen, Jukka, Virtanen, Kirsi, Volanen, Iina, Scheinin, Mika, Rinne, Juha O.

“…Purpose α 2C -Adrenoceptors share inhibitory presynaptic functions with the more abundant α 2A -adrenoceptor subtype, but they also have widespread…”
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Test-retest reliability of ^sup 11^C-ORM-13070 in PET imaging of [alpha]^sub 2C^-adrenoceptors in vivo in the human brain by Lehto, Jussi, Virta, Jere R, Oikonen, Vesa, Roivainen, Anne, Luoto, Pauliina, Arponen, Eveliina, Helin, Semi, Hietamäki, Johanna, Holopainen, Aila, Kailajärvi, Marita, Peltonen, Juha M, Rouru, Juha, Sallinen, Jukka, Virtanen, Kirsi, Volanen, Iina, Scheinin, Mika, Rinne, Juha O

“…[alpha]^sub 2C^-Adrenoceptors share inhibitory presynaptic functions with the more abundant [alpha]^sub 2A^-adrenoceptor subtype, but they also have widespread…”
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1-^sup 11^C-Methyl-4-Piperidinyl-N-Butyrate Radiation Dosimetry in Humans by Dynamic Organ-Specific Evaluation by Virta, Jere R, Tolvanen, Tuula, Någren, Kjell, Brück, Anna, Roivainen, Anne, Rinne, Juha O

“…Deficits of cholinergic neurotransmission contribute to various neurologic and psychiatric conditions. The neurotransmitter acetylcholine is hydrolyzed in the…”
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