Search Results - "Virone, A"

Rheumatoid Factor and Disease Activity Are Independent Predictors of Lymphoma in Primary Sjögren's Syndrome by Nocturne, G., Virone, A., Ng, Wan‐Fai, Le Guern, V., Hachulla, E., Cornec, D., Daien, C., Vittecoq, O., Bienvenu, B., Marcelli, C., Wendling, D., Amoura, Z., Dhote, R., Lavigne, C., Fior, R., Gottenberg, J. E., Seror, R., Mariette, X.

“…Objective To define parameters predictive of lymphoma development in patients with primary Sjögren's syndrome (SS). Methods A multicenter case–control survey…”
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The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells by Thijssen, R, ter Burg, J, van Bochove, G G W, de Rooij, M F M, Kuil, A, Jansen, M H, Kuijpers, T W, Baars, J W, Virone-Oddos, A, Spaargaren, M, Egile, C, van Oers, M H J, Eldering, E, Kersten, M J, Kater, A P

“…The phosphoinositide 3-kinases (PI3Ks) are critical components of the B-cell receptor (BCR) pathway and have an important role in the pathobiology of chronic…”
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The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells by Thijssen, R, Ter Burg, J, van Bochove, G G W, de Rooij, M F M, Kuil, A, Jansen, M H, Kuijpers, T W, Baars, J W, Virone-Oddos, A, Spaargaren, M, Egile, C, van Oers, M H J, Eldering, E, Kersten, M J, Kater, A P

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Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the APPRAISE study by D'Agostino, Maria-Antonietta, Wakefield, Richard J, Berner-Hammer, Hilde, Vittecoq, Olivier, Filippou, Georgios, Balint, Peter, Möller, Ingrid, Iagnocco, Annamaria, Naredo, Esperanza, Østergaard, Mikkel, Boers, Maarten, Gaillez, Corine, Van Holder, Karina, Le Bars, Manuela

“…To study the responsiveness of a combined power Doppler and greyscale ultrasound (PDUS) score for assessing synovitis in biologic-naïve patients with…”
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Stable cell line of T-SV40 immortalized human glomerular visceral epithelial cells by Delarue, Françoise, Virone, Angela, Hagege, Jacqueline, Lacave, Roger, Peraldi, Marie-Nëlle, Adida, Colette, Rondeau, Eric, Feunteun, Jean, Sraer, Jean-Daniel

“…Stable cell line of T-SV40 immortalized human glomerular visceral epithelial cells. Human subcultures (third passage) of glomerular visceral epithelial cells…”
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In vitro and in vivo effects of UP 269‐6, a new potent orally active nonpeptide angiotensin II receptor antagonist, on vascular smooth muscle cell proliferation by Virone‐Oddos, A., Desangle, V., Provost, D., Cazes, M., Caussade, F., Cloarec, A.

“…1 The present studies were designed to measure the affinity of UP 269‐6, a newly developed angiotensin AT1 receptor antagonist, for vascular AT1 receptors from…”
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In vitro pharmacological characterization of UP 269-6, a novel nonpeptide angiotensin II receptor antagonist by Caussade, F, Virone-Oddos, A, Delchambre, C, Cazes, M, Versigny, A, Cloarec, A

“…f1p4in vitro pharmacology of UP 269-6, a novel nonpeptide angiotensin II antagonist, was examined in radioligand binding and functional isolated tissue assays…”
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149 Characterization of novel series of selective PI3Kalpha and PI3Kalpha/mTOR-dual inhibitors by Foster, P, Rice, K, Bussenius, J, Jaeger, C, Nguyen, L, Virone-Oddos, A, Markby, D

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115 Discovery and characterization of PI3Kbeta isoform-selective inhibitors by Virone-Oddos, A, Halley, F, Delorme, C, Bonnevaux, H, Nicolas, J.P, Karlsson, A, Abecassis, P.Y, Vincent, L, Lengauer, C

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Évolution des biomarqueurs associés au risque cardiovasculaire sous anti-TNF versus autres biothérapies dans la polyarthrite rhumatoïde: étude ancillaire de l’essai ROC by Virone, A., Bastard, J.P., Fellahi, S., Capeau, J., Rouanet, S., Sibilia, J., Ravaud, P., Berenbaum, F., Gottenberg, J.E., Sellam, J.

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Abcès musculaires aseptiques associés à un syndrome myélodysplasique by Mirouse, A., Virone, A., Gobert, D., Soussan, M., Braun, T., Gardin, C., Fenaux, P., Mekinian, A., Fain, O.

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Erratum: The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells by Thijssen, R, ter Burg, J, van Bochove, G G W, de Rooij, M F M, Kuil, A, Jansen, M H, Kuijpers, T W, Baars, J W, Virone-Oddos, A, Spaargaren, M, Egile, C, van Oers, M H J, Eldering, E, Kersten, M J, Kater, A P

“…Correction to: Leukemia (2016) 30, 337–345; doi:10.1038/leu.2015.241; Published 10 November 2015 Following the publication of this article, the authors noted…”
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The pan phosphoinositide 3-kinase mammalian target of rapamycin inhibitor SAR245409 by Spaargaren, M, de Rooij, M F M, Kuil, A, Baars, J W, Kater, A P, Egile, C, Thijssen, R, Kersten, M J, ter Burg, J, Virone-Oddos, A, Eldering, E, van Bochove, G G W, Kuijpers, T W, van Oers, M H J, Jansen, M H

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Synthesis and angiotensin II receptor antagonist activity of C-linked pyrimidine derivatives by Nicolaï, E, Curé, G, Goyard, J, Kirchner, M, Teulon, JM, Versigny, A, Cazes, M, Virone-Oddos, A, Caussade, F, Cloarec, A

“…The synthesis and pharmacological activity of nonpeptide angiotensin II (Ang II) receptor antagonists are presented. These 3- N-substituted pyrimidine-4(3…”
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A structure-based approach to selective PI3Kbeta inihibition by Bertrand, T., Marquette, J. -P., Karlsson, A., Michot, N., Virone-Oddos, A., Halley, F.

“…Abstract only…”
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Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists by Nicolai, Eric, Goyard, Joel, Benchetrit, Thierry, Teulon, Jean Marie, Caussade, Francois, Virone, Angela, Delchambre, Chantal, Cloarec, Alix

“…A series of 1-benzylbenzimidazole and 3-benzylimidazo[4,5-b]pyridine substituted in the 2-position by an alkanoic or mercaptoalkanoic acid chain was…”
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Intracellular expression of an antibody fragment-neutralizing p21 Ras promotes tumor regression by COCHET, O, KENIGSBERG, M, DELUMEAU, I, VIRONE-ODDOS, A, MULTON, M.-C, FRIDMAN, W. H, SCHWEIGHOFFER, F, TEILLAUD, J.-L, TOCQUE, B

“…Mutated ras genes are found in a large number of human tumors and, therefore, constitute one of the primary targets for cancer treatment. Microinjection of the…”
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Metastatic phenotype of murine tumor cells expressing different cooperating oncogenes by Virone, A, Monier, R, Zerial, A, Lavelle, F, Feunteun, J

“…Four murine cellular tumor models expressing various combinations of oncogenes (SV40 large T and v-Ha-ras, SV40 large T and v-src, SV40 large T and neu,…”
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Transfert du gène p53 sauvage dans une lignée humaine de carcinome épidermoïde by Badie, C, Bourhis, J, Bosq, J, Haddada, H, Chiron, M, Virone, A, Vassal, G

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Cancer gene therapy mediated by CTS1, a p53 derivative: advantage over wild-type p53 in growth inhibition of human tumors overexpressing MDM2 by Bougeret, C, Virone-Oddos, A, Adeline, E, Lacroix, F, Lefranc, C, Ferrero, L, Huet, T

“…Recently, a new p53 derivative has been designed, namely chimeric tumor suppressor 1 (CTS1), in which the p53 domains that are known to mediate p53…”
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