Search Results - "Virmani, Richa"
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Artificial Intelligence in Surveillance, Diagnosis, Drug Discovery and Vaccine Development against COVID-19
Published in Pathogens (Basel) (18-08-2021)“…As of August 6th, 2021, the World Health Organization has notified 200.8 million laboratory-confirmed infections and 4.26 million deaths from COVID-19, making…”
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Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist
Published in Nature communications (01-10-2024)“…The melanocortin receptor 4 (MC4R) belongs to the melanocortin receptor family of G-protein coupled receptors and is a key switch in the leptin-melanocortin…”
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3
Identification of Ser/Thr kinase and forkhead associated domains in Mycobacterium ulcerans: characterization of novel association between protein kinase Q and MupFHA
Published in PLoS neglected tropical diseases (01-11-2014)“…Mycobacterium ulcerans, the causative agent of Buruli ulcer in humans, is unique among the members of Mycobacterium genus due to the presence of the virulence…”
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4
Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis
Published in NPJ biofilms and microbiomes (07-03-2017)“…PrkC is a conserved Ser/Thr protein kinase encoded in Bacillus anthracis genome. PrkC is shown to be important for B. anthracis pathogenesis, but little is…”
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Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers
Published in Environmental microbiology (01-01-2018)“…Summary Tuberculosis (TB) is primarily associated with decline in immune health status. As gut microbiome (GM) is implicated in the regulation of host immunity…”
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Phosphorylation-mediated regulation of the Bacillus anthracis phosphoglycerate mutase by the Ser/Thr protein kinase PrkC
Published in Biochemical and biophysical research communications (12-07-2023)“…Bacillus anthracis Ser/Thr protein kinase PrkC is necessary for phenotypic memory and spore germination, and the loss of PrkC-dependent phosphorylation events…”
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GroEL Mediates Folding of Bacillus anthracis Serine/Threonine Protein Kinase, PrkC
Published in Indian journal of microbiology (01-12-2018)“…Bacillus anthracis causes anthrax in human and animals. Both, signaling system such as two component system and endogenous chaperone system such as GroEL–GroES…”
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Effect of Homocysteine on Biofilm Formation by Mycobacteria
Published in Indian journal of microbiology (01-09-2018)“…Mycobacteria show peculiar aggregated outgrowth like biofilm on the surface of solid or liquid media. Biofilms harbor antibiotic resistant bacteria in a…”
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Human Milk Microbiota: Transferring the Antibiotic Resistome to Infants
Published in Indian journal of microbiology (01-12-2019)“…Commensal bacterial population is believed to be a reservoir for antibiotic resistance genes (ARGs). The infant gut microbiota has relatively higher abundance…”
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Methylation of two-component response regulator MtrA in mycobacteria negatively modulates its DNA binding and transcriptional activation
Published in Biochemical journal (11-12-2020)“…Post-translational modifications such as phosphorylation, nitrosylation, and pupylation modulate multiple cellular processes in Mycobacterium tuberculosis…”
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The Ser/Thr protein kinase PrkC imprints phenotypic memory in Bacillus anthracis spores by phosphorylating the glycolytic enzyme enolase
Published in The Journal of biological chemistry (31-05-2019)“…Bacillus anthracis is the causative agent of anthrax in humans, bovine, and other animals. B. anthracis pathogenesis requires differentiation of dormant spores…”
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Systematic Analysis of Mycobacterial Acylation Reveals First Example of Acylation-mediated Regulation of Enzyme Activity of a Bacterial Phosphatase
Published in The Journal of biological chemistry (23-10-2015)“…Protein lysine acetylation is known to regulate multiple aspects of bacterial metabolism. However, its presence in mycobacterial signal transduction and…”
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Regulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase
Published in Scientific reports (23-07-2013)“…Mycobacterium tuberculosis modulates expression of various metabolism-related genes to adapt in the adverse host environment. The gene coding for M…”
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Tuning the Mycobacterium tuberculosis Alternative Sigma Factor SigF through the Multidomain Regulator Rv1364c and Osmosensory Kinase Protein Kinase D
Published in Journal of bacteriology (01-04-2019)“…Bacterial alternative sigma factors are mostly regulated by a partner-switching mechanism. Regulation of the virulence-associated alternative sigma factor SigF…”
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Identification of Ser/Thr kinase and Forkhead Associated Domains in Mycobacterium ulcerans: Characterization of Novel Association between Protein Kinase Q and MupFHA: e3315
Published in PLoS neglected tropical diseases (01-11-2014)“…Background Mycobacterium ulcerans, the causative agent of Buruli ulcer in humans, is unique among the members of Mycobacterium genus due to the presence of the…”
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