Search Results - "Virgilio, F. Di"

The P2X7 receptor is a key modulator of aerobic glycolysis by Amoroso, F, Falzoni, S, Adinolfi, E, Ferrari, D, Di Virgilio, F

“…Ability to adapt to conditions of limited nutrient supply requires a reorganization of the metabolic pathways to balance energy generation and production of…”
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Extracellular purines, purinergic receptors and tumor growth by Di Virgilio, F, Adinolfi, E

“…Virtually, all tumor cells as well as all immune cells express plasma membrane receptors for extracellular nucleosides (adenosine) and nucleotides (ATP, ADP,…”
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purinergic receptor P2Y₂ receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation by Müller, T, Robaye, B, Vieira, R.P, Ferrari, D, Grimm, M, Jakob, T, Martin, S.F, Di Virgilio, F, Boeynaems, J.‐M, Virchow, J.C, Idzko, M

“…To cite this article: Müller T, Robaye B, Vieira RP, Ferrari D, Grimm M, Jakob T, Martin SF, Di Virgilio F, Boeynaems J‐M, Virchow JC, Idzko M. The purinergic…”
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ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival by Gilbert, SM, Oliphant, CJ, Hassan, S., Peille, AL, Bronsert, P., Falzoni, S., Di Virgilio, F., McNulty, S., Lara, R.

“…The ATP-gated receptor P2X 7 is expressed in multiple malignant tumours including neuroblastoma, melanoma, prostate, lung and breast. P2X 7 has a significant…”
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ATP in the tumour microenvironment drives expression of nfP2X 7 , a key mediator of cancer cell survival by Gilbert, S M, Oliphant, C J, Hassan, S, Peille, A L, Bronsert, P, Falzoni, S, Di Virgilio, F, McNulty, S, Lara, R

“…The ATP-gated receptor P2X is expressed in multiple malignant tumours including neuroblastoma, melanoma, prostate, lung and breast. P2X has a significant role…”
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Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation by Bours, M J L, Swennen, E L R, Di Virgilio, F, Cronstein, B N, Dagnelie, P C

“…Human health is under constant threat of a wide variety of dangers, both self and nonself. The immune system is occupied with protecting the host against such…”
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Reply to: 'The discovery of a new class of synaptic transmitters in smooth muscle fifty years ago and amelioration of coronary artery thrombosis' by Abbracchio, M. P., Boeynaems, J.-M., Cattaneo, M., Virgilio, F. Di, Illes, P., Inoue, K., Jacobson, K. A., Teresa Miras-Portugal, M., Ralevic, V., Robson, S. C., Verkhratsky, A., Zimmermann, H.

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ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment by Bianchi, G, Vuerich, M, Pellegatti, P, Marimpietri, D, Emionite, L, Marigo, I, Bronte, V, Di Virgilio, F, Pistoia, V, Raffaghello, L

“…Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenosine and ATP. Physiological significance of this biochemical…”
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High glucose modulates P2X7 receptor-mediated function in human primary fibroblasts by SOLINI, A, CHIOZZI, P, FALZONI, S, MORELLI, A, FELLIN, R, DI VIRGILIO, F

“…Purinergic receptors are a family of newly characterized plasma membrane molecules involved in several and as yet only partially known cellular functions such…”
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Comparison of the incidence of intra-operative haemorrhage from ovarian vessels during ovariectomy and ovariohysterectomy of dogs and cats performed by inexperienced surgeons using surgeon's and constrictor knots by Belluzzi, E, Santos, MA, Jifcovici, A, Redolfi, G, Di Virgilio, F, Deneuche, A, Bongartz, AL, Caraty, JA

“…To compare the incidence of intra-operative haemorrhage from ovarian vessels during ovariectomy (OV) and ovariohysterectomy (OVH) in dogs and cats performed by…”
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Nimodipine inhibits IL‐1β release stimulated by amyloid β from microglia by Sanz, JM, Chiozzi, P, Colaianna, M, Zotti, M, Ferrari, D, Trabace, L, Zuliani, G, Di Virgilio, F

“…BACKGROUND AND PURPOSE There is growing evidence that inflammation plays a major role in the pathogenesis of neural damage caused by deposition of amyloid β…”
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How to classify the covid-19 phenotype: a response from "the first soldier in the first trench" in Lombardy, north-western Italy by Gallenga, C E, Contini, C, Tana, M, D'Eliseo, D, Giuliani, A L, Di Virgilio, F, Paglia, S

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Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor by MURGIA, M, HANAU, S, PIZZO, P, RIPPA, M, DI VIRGILIO, F

“…The effects of oxidized ATP (oATP) on responses triggered by extracellular adenosine 5'-triphosphate (ATPe) were investigated in the mouse macrophage-like cell…”
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Modulation of P2X 7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule by Ferrari, D, Pizzirani, C, Gulinelli, S, Callegari, G, Chiozzi, P, Idzko, M, Panther, E, Di Virgilio, F

“…Background and purpose: P2X 7 is a membrane receptor for extracellular ATP which is highly expressed in dendritic cells, macrophages and microglia where it…”
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Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages by Ferrari, D, Chiozzi, P, Falzoni, S, Dal Susino, M, Melchiorri, L, Baricordi, OR, Di Virgilio, F

“…Extracellular ATP (ATPe) is known to cause release of processed IL-1 beta from LPS-treated macrophages and microglial cells. IL-1 beta release is fast and…”
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Extracellular ATP Induces a Distorted Maturation of Dendritic Cells and Inhibits Their Capacity to Initiate Th1 Responses by la Sala, Andrea, Ferrari, Davide, Corinti, Silvia, Cavani, Andrea, Di Virgilio, Francesco, Girolomoni, Giampiero

“…Dendritic cells (DCs) express functional purinergic receptors, but the effects of purine nucleotides on DC functions have been marginally investigated. In this…”
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New pathways for reactive oxygen species generation in inflammation and potential novel pharmacological targets by Di Virgilio, F

“…Oxidative agents are generated in large amounts during inflammation. These highly reactive intermediates interact with several extracellular and intracellular…”
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Characterization of volume-sensitive taurine- and Cl(-)-permeable channels by Galietta, L J, Falzoni, S, Di Virgilio, F, Romeo, G, Zegarra-Moran, O

“…Volume-sensitive Cl- channels [ICl(vol)] were studied using taurine efflux and patch-clamp experiments in 9HTEo- human tracheal cells. Cells were stimulated…”
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Mechanism of human sperm activation by extracellular ATP by Foresta, C, Rossato, M, Chiozzi, P, Di Virgilio, F

“…We have identified the mechanism whereby extracellular ATP (ATPe) triggers the acrosome reaction in human spermatozoa. This nucleotide opens a ligand-gated ion…”
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Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells by Di Virgilio, F, Fasolato, C, Steinberg, T H

“…The neuroblastoma-like cell line N2A and the pheochromocytoma-like cell line PC12 excrete about 20-25% of the intracellular fluorescent Ca2+ indicator fura-2…”
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