Search Results - "Virchow Jr, J. C."

Effect of a specific cysteinyl leukotriene-receptor 1-antagonist (montelukast) on the transmigration of eosinophils across human umbilical vein endothelial cells by Virchow Jr, J. C., Faehndrich, S., Nassenstein, C., Bock, S., Matthys, H., Luttmann, W.

“…Background Leukotrienes have been implicated in the selective infiltration of eosinophils into the bronchial mucosa in asthma. Objective We studied whether…”
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Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells by Prasse, A., Georges, C. G., Biller, H., Hamm, H., Matthys, H., Luttmann, W., Virchow Jr, J. C.

“…The pathogenesis of pulmonary sarcoidosis has been related to an increased production of Th1‐like cytokines. However, cytokine expression in sarcoidosis has…”
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Endobronchial secretion of interleukin-13 following local allergen challenge in atopic asthma: relationship to interleukin-4 and eosinophil counts by Kroegel, C, Julius, P, Matthys, H, Virchow JC, , Jr, Luttmann, W

“…We investigated the secretion of interleukin (IL)-13 into the airways in 10 mild allergic asthmatics by employing local allergen challenge, and compared the…”
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T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma by Walker, C, Virchow, JC, Jr, Bruijnzeel, PL, Blaser, K

“…Lymphokines derived from activated T cells regulate the proliferation and postmitotic differentiation of eosinophils in vitro. We investigated whether…”
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Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability by Luttmann, W, Knoechel, B, Foerster, M, Matthys, H, Virchow, JC, Jr, Kroegel, C

“…To study the effect of IL-13 on CD69 expression and cell viability in human eosinophils, purified human peripheral blood eosinophils from healthy donors were…”
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Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts by Borowski, A., Kuepper, M., Horn, U., Knüpfer, U., Zissel, G., Höhne, K., Luttmann, W., Krause, S., Virchow Jr, J. C., Friedrich, K.

“…Summary Background IL‐13 promotes acute allergic asthma and is discussed to play a role in late asthmatic features such as fibrotic processes and airway…”
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Sputum eosinophils from asthmatics express ICAM‐1 and HLA‐DR by HANSEL, T. T., BRAUNSTEIN, J. B., WALKER, C., BLASER, K., BRUIJNZEEL, P. L. B., VIRCHOW, J.‐C., VIRCHOW, C.

“…SUMMARY Sputum from symptomatic asthmatics is a rich source of eosinophils from the respiratory tract. Following liquefaction of sputum with dithioerythritol…”
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T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma by Virchow, Jr, J C, Walker, C, Hafner, D, Kortsik, C, Werner, P, Matthys, H, Kroegel, C

“…Increasing evidence suggests a role for activated T cells and cytokines in the regulation of eosinophilic inflammation in asthma. In this study, we…”
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Increase in killer-specific secretory protein of 37 kDa in bronchoalveolar lavage fluid of allergen-challenged patients with atopic asthma by Kuepper, M., Bratke, K., Julius, P., Ogawa, K., Nagata, K., Luttmann, W., Virchow Jr, J. C.

“…Summary Background Atopic asthma is linked to a T‐helper type 2 dominated pathogenesis, but there is increasing evidence of Th1/Tc1‐mediated processes in the…”
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Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage by Walker, C, Bode, E, Boer, L, Hansel, T T, Blaser, K, Virchow, Jr, J C

“…Activation of lymphocyte subpopulations was determined in conjunction with levels of cytokines in peripheral blood and bronchoalveolar lavage (BAL) of…”
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Inflammatory determinants of asthma severity: Mediator and cellular changes in bronchoalveolar lavage fluid of patients with severe asthma by Virchow, J.Christian, Kroegel, Claus, Walker, Christoph, Matthys, Heinrich

“…Cellular and mediator profiles in bronchoalveolar lavage have not been compared systematically between patients with asthma of different severities, mainly…”
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A prospective trial using salivary-theophylline levels to guide asthma therapy by Virchow, Jr, J C, Mansfeld, J, Matthys, H, Virchow, Sr, C

“…In three prospectively designed studies, first saliva (SA) samples were collected simultaneously with serum (SE) from 86 children who received slow-release…”
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Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I) by Kroegel, C, Virchow JC, , Jr, Luttmann, W, Walker, C, Warner, JA

“…Increasing evidence has accumulated to suggest that eosinophils play a key role in the pathogenesis of asthma and other pulmonary diseases by damaging…”
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CD14 expression and soluble CD14 after segmental allergen provocation in atopic asthma by Virchow JC, , Jr, Julius, P, Matthys, H, Kroegel, C, Luttmann, W

“…Allergic asthma is associated with the recruitment of activated inflammatory cells after allergen challenge. Surface expression of CD14 has been proposed as a…”
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CD69 surface expression on human lung eosinophils after segmental allergen provocation by Julius, P, Luttmann, W, Knoechel, B, Kroegel, C, Matthys, H, Virchow JC, , Jr

“…CD69 expression on eosinophils is observed in asthma and has been proposed as a marker of eosinophil activation. The role of allergens in the in vivo…”
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Pulmonary function, activated T cells, peripheral blood eosinophilia, and serum activity for eosinophil survival in vitro: A longitudinal study in bronchial asthma by Virchow, Jr, J C, Oehling, A, Boer, L, Hansel, T T, Werner, P, Matthys, H, Blaser, K, Walker, C

“…A close correlation among the number of activated, peripheral blood T helper cells, eosinophilia, and airflow obstruction has been reported in patients with…”
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Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II) by Kroegel, C, Warner, JA, Virchow JC, , Jr, Matthys, H

“…The second part of this review on eosinophils focuses on biological cell functions and surveys the various deleterious mechanisms involved in the…”
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Antiasthma drug delivery : what is on the horizon ? by VIRCHOW, J.-C. JR, KROEGEL, C, MATTHYS, H

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Effects of TGF‐β on Eosinophil Chemotaxis by Luttmann, W, Franz, P, Matthys, H, Virchow, Jr, J C

“…Transforming growth factor‐β (TGF‐β), which can decrease the effects of interleukin (IL)‐3, IL‐5 and granulocyte–macrophage colony‐stimulating factor (GM‐CSF)…”
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Comparison of sputum-ECP levels in bronchial asthma and chronic bronchitis by Virchow, Jr, J C, Kroegel, C, Hage, U, Kortsik, C, Matthys, H, Werner, P

“…Eosinophil cationic protein (ECP) is a cationic protein secreted by eosinophils with toxic properties for the respiratory epithelium. Sputum-ECP levels have…”
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