Search Results - "Vinogradov, V. S."
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Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV‑1 Infection
Published in Molecular pharmaceutics (07-12-2015)“…Nucleoside reverse transcriptase inhibitors (NRTIs) are an integral part of the current antiretroviral therapy (ART), which dramatically reduced the mortality…”
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Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents
Published in Gene therapy (2000)“…Cationic copolymers consisting of polycations linked to non-ionic polymers are evaluated as non-viral gene delivery systems. These copolymers are known to…”
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Hadron polarization control at integer spin resonances in synchrotrons using a spin navigator
Published in Physical review. Accelerators and beams (01-06-2021)“…We consider the capability of flexible spin-transparent polarization control and manipulation in conventional synchrotrons at integer spin resonances by means…”
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Amphiphilic Cationic Nanogels as Brain-Targeted Carriers for Activated Nucleoside Reverse Transcriptase Inhibitors
Published in Journal of neuroimmune pharmacology (01-03-2015)“…Progress in AIDS treatment shifted emphasis towards limiting adverse effects of antiviral drugs while improving the treatment of hard-to-reach viral…”
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Vortex States with Linear Electronic Spectrum in IV–VI Semiconductor Structures
Published in Bulletin of the Lebedev Physics Institute (01-02-2019)“…It is theoretically shown that spin-polarized vortex states with linear electronic spectrum can exist in planar homogeneous structures of two-band…”
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Polyethyleneimine grafted with pluronic P85 enhances Ku86 antisense delivery and the ionizing radiation treatment efficacy in vivo
Published in Gene therapy (01-11-2004)“…In an effort to improve the efficacy of antisense delivery, we evaluated polyethyleneimine (PEI, 2 kDa) alone or grafted with nonionic amphiphilic block…”
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Proton-Spin-Flipping System Based on Orbit-Steerer Dipoles in the Nuclotron/JINR Operating at the γG = 7 Spin Resonance
Published in JETP letters (01-09-2023)“…We propose a system to produce multiple spin reversals of a polarized proton beam based on orbit-steerer dipoles already installed in the Nuclotron, a…”
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High-Energy Part of the Accelerator for the DARIA Compact Neutron Source: Drift Tube Linac
Published in Surface investigation, x-ray, synchrotron and neutron techniques (01-08-2023)“…Within the scope of the DARIA project (neutron source Dedicated to Academic Research and Industrial Application), a pulsed proton accelerator is being…”
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Block and Graft Copolymers and Nanogel™ Copolymer Networks for DNA Delivery into Cell
Published in Journal of drug targeting (2000)“…AbstractSelf-assembling complexes from nucleic acids and synthetic polymers are evaluated for plasmid and oligonucleotide (oligo) delivery. Polycations having…”
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Classification of Reconfigurable Parallel Mechanisms
Published in Russian engineering research (01-05-2020)“…The theoretically possible reconfigurable parallel mechanisms are classified, in terms of the layout of guides on the base. Formulas are derived for the…”
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Formalized Configurational Calculations of Parallel Mechanisms
Published in Russian engineering research (01-08-2018)“…Theoretically possible configurations of parallel mechanisms are classified, taking account of the hinge arrangement at the base and the moving platform. This…”
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Temperature Dependence of the Vibrational Mode of Pb1 –xSnxTe Films Grown by MBE on the GaAs/CdTe Hybrid Substrate
Published in Bulletin of the Lebedev Physics Institute (2020)“…Reflectance spectra of thin Pb 1 – x Sn x Te films (~60 nm) with x = 0.25, 0.53, and 0.59, grown by MBE on hybrid GaAs/CdTe substrates, are measured in the…”
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Altered Organ Accumulation of Oligonucleotides Using Polyethyleneimine Grafted With Poly(ethylene Oxide) or Pluronic as Carriers
Published in Journal of drug targeting (01-03-2002)“…Passive targeting provides a simple strategy based on natural properties of the carriers to deliver DNA molecules to desired compartments. Polyethylenimine…”
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Parameter for evaluation of the layout arrangement of the metalworking machines with parallel kinematics
Published in Journal of machinery manufacture and reliability (01-09-2017)“…A parameter was proposed to make it possible to provide quantitative evaluation of the share of the volume of technological working space in the common…”
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Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization
Published in The Journal of pharmacology and experimental therapeutics (01-11-2001)“…Pluronic block copolymer, P85, inhibits the P-glycoprotein (Pgp) drug efflux system and increases the permeability of a broad spectrum of drugs in the…”
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Dimension of an optimum impurity cluster and multiple-occupancy corrections in the theory of scattering of vibrational excitations in a solid solution
Published in Physics of the solid state (01-11-2007)“…A relationship is derived for the correlation length L determining the size of the region in a solid solution in which excitations are scattered coherently…”
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Nanogels for Oligonucleotide Delivery to the Brain
Published in Bioconjugate chemistry (01-01-2004)“…Systemic delivery of oligonucleotides (ODN) to the central nervous system is needed for development of therapeutic and diagnostic modalities for treatment of…”
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Self-Assembly of Polyamine−Poly(ethylene glycol) Copolymers with Phosphorothioate Oligonucleotides
Published in Bioconjugate chemistry (01-11-1998)“…The cationic copolymers for DNA delivery were synthesized by conjugating poly(ethylene glycol) (PEG) and polyamines: polyspermine (PSP) and polyethyleneimine…”
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Polypeptide Point Modifications with Fatty Acid and Amphiphilic Block Copolymers for Enhanced Brain Delivery
Published in Bioconjugate chemistry (01-07-2005)“…There is a tremendous need to enhance delivery of therapeutic polypeptides to the brain to treat disorders of the central nervous system (CNS). The brain…”
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Concept of the noncoenzymatic thiamine effect
Published in Medical hypotheses (01-12-1997)“…The experimental and clinical data on different aspects of vitamin and hormone relationships have been summarized in the form of a general concept of the…”
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