Search Results - "Vinod, P. K."

Network-level analysis of ageing and its relationship with diseases and tissue regeneration in the mouse liver by Porukala, Manisri, Vinod, P. K.

“…The liver plays a vital role in maintaining whole-body metabolic homeostasis, compound detoxification and has the unique ability to regenerate itself…”
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Gene expression signatures of stepwise progression of Hepatocellular Carcinoma by Porukala, Manisri, Vinod, P K

“…The molecular pathogenesis of Hepatocellular Carcinoma (HCC) is a complex process progressing from premalignant stages to cancer in a stepwise manner. Mostly,…”
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Network-based metabolic characterization of renal cell carcinoma by Pandey, Nishtha, Lanke, Vinay, Vinod, P. K.

“…An emerging hallmark of cancer is metabolic reprogramming, which presents opportunities for cancer diagnosis and treatment based on metabolism. We performed a…”
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Atypical Flexibility in Dynamic Functional Connectivity Quantifies the Severity in Autism Spectrum Disorder by Harlalka, Vatika, Bapi, Raju S, Vinod, P K, Roy, Dipanjan

“…Resting-state functional connectivity (FC) analyses have shown atypical connectivity in autism spectrum disorder (ASD) as compared to typically developing…”
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Network diffusion-based approach for survival prediction and identification of biomarkers using multi-omics data of papillary renal cell carcinoma by Shetty, Keerthi S., Jose, Aswin, Bani, Mihir, Vinod, P. K.

“…Identification of cancer subtypes based on molecular knowledge is crucial for improving the patient diagnosis, prognosis, and treatment. In this work, we…”
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Machine Learning Based Clinical Decision Support System for Early COVID-19 Mortality Prediction by Karthikeyan, Akshaya, Garg, Akshit, Vinod, P. K., Priyakumar, U. Deva

“…The coronavirus disease 2019 (COVID-19), caused by the virus SARS-CoV-2, is an acute respiratory disease that has been classified as a pandemic by the World…”
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COVID-19 Risk Stratification and Mortality Prediction in Hospitalized Indian Patients: Harnessing clinical data for public health benefits by Alle, Shanmukh, Kanakan, Akshay, Siddiqui, Samreen, Garg, Akshit, Karthikeyan, Akshaya, Mehta, Priyanka, Mishra, Neha, Chattopadhyay, Partha, Devi, Priti, Waghdhare, Swati, Tyagi, Akansha, Tarai, Bansidhar, Hazarik, Pranjal Pratim, Das, Poonam, Budhiraja, Sandeep, Nangia, Vivek, Dewan, Arun, Sethuraman, Ramanathan, Subramanian, C, Srivastava, Mashrin, Chakravarthi, Avinash, Jacob, Johnny, Namagiri, Madhuri, Konala, Varma, Dash, Debasish, Sethi, Tavpritesh, Jha, Sujeet, Agrawal, Anurag, Pandey, Rajesh, Vinod, P K, Priyakumar, U Deva

“…The variability of clinical course and prognosis of COVID-19 highlights the necessity of patient sub-group risk stratification based on clinical data. In this…”
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Mathematical modelling of reversible transition between quiescence and proliferation by Pandey, Nishtha, Vinod, P K

“…Cells switch between quiescence and proliferation states for maintaining tissue homeostasis and regeneration. At the restriction point (R-point), cells become…”
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Inferring miRNA sponge modules across major neuropsychiatric disorders by Balasubramanian, Rami, Vinod, P. K.

“…The role of non-coding RNAs in neuropsychiatric disorders (NPDs) is an emerging field of study. The long non-coding RNAs (lncRNAs) are shown to sponge the…”
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PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit by Hégarat, Nadia, Vesely, Clare, Vinod, P K, Ocasio, Cory, Peter, Nisha, Gannon, Julian, Oliver, Antony W, Novák, Béla, Hochegger, Helfrid

“…Entry into mitosis is triggered by activation of Cdk1 and inactivation of its counteracting phosphatase PP2A/B55. Greatwall kinase inactivates PP2A/B55 via its…”
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Ayu-Characterization of healthy aging from neuroimaging data with deep learning and rsfMRI by Borkar, Kushal, Chaturvedi, Anusha, Vinod, P. K., Bapi, Raju Surampudi

“…Estimating brain age and establishing functional biomarkers that are prescient of cognitive declines resulting from aging and different neurological diseases…”
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Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease by Lanke, Vinay, Moolamalla, S T R, Roy, Dipanjan, Vinod, P K

“…Alzheimer's disease (AD) is a neurodegenerative disorder contributing to rapid decline in cognitive function and ultimately dementia. Most cases of AD occur in…”
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Exploring Histological Similarities Across Cancers From a Deep Learning Perspective by Menon, Ashish, Singh, Piyush, Vinod, P K, Jawahar, C V

“…Histopathology image analysis is widely accepted as a gold standard for cancer diagnosis. The Cancer Genome Atlas (TCGA) contains large repositories of…”
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Systems-level analysis of transcriptome reorganization during liver regeneration by Porukala, Manisri, Vinod, P K

“…Tissue homeostasis and regeneration depend on the reversible transitions between quiescence (G0) and proliferation. The liver has a remarkable capacity to…”
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MolGPT: Molecular Generation Using a Transformer-Decoder Model by Bagal, Viraj, Aggarwal, Rishal, Vinod, P K, Priyakumar, U Deva

“…Application of deep learning techniques for generation of molecules, termed as inverse molecular design, has been gaining enormous traction in drug design. The…”
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Value added biodiesel for corrosion inhibition by Iyyappan, S, Kumar, K P Vinod, Ponram, P

“…Biodiesel is one of the prospective fuels, potentially capable of substituting petroleum fuel. Nevertheless, systems using this bioenergy resource are prone to…”
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AI-Assisted Screening of Oral Potentially Malignant Disorders Using Smartphone-Based Photographic Images by Talwar, Vivek, Singh, Pragya, Mukhia, Nirza, Shetty, Anupama, Birur, Praveen, Desai, Karishma M, Sunkavalli, Chinnababu, Varma, Konala S, Sethuraman, Ramanathan, Jawahar, C V, Vinod, P K

“…The prevalence of oral potentially malignant disorders (OPMDs) and oral cancer is surging in low- and middle-income countries. A lack of resources for…”
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A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis by Kapuy, Orsolya, Vinod, P K, Mandl, József, Bánhegyi, Gábor

“…Decision-making between life and death is one of the most important tasks of cells to maintain their genetic integrity. While the surviving mechanism is driven…”
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Molecular mechanisms creating bistable switches at cell cycle transitions by Verdugo, Anael, Vinod, P. K., Tyson, John J., Novak, Bela

“…Progression through the eukaryotic cell cycle is characterized by specific transitions, where cells move irreversibly from stage i−1 of the cycle into stage i…”
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Pan-Renal Cell Carcinoma classification and survival prediction from histopathology images using deep learning by Tabibu, Sairam, Vinod, P. K., Jawahar, C. V.

“…Histopathological images contain morphological markers of disease progression that have diagnostic and predictive values. In this study, we demonstrate how…”
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