Search Results - "Vinnikov, Ilya A"

Delivery of functional exogenous proteins by plant-derived vesicles to human cells in vitro by Garaeva, Luiza, Kamyshinsky, Roman, Kil, Yury, Varfolomeeva, Elena, Verlov, Nikolai, Komarova, Elena, Garmay, Yuri, Landa, Sergey, Burdakov, Vladimir, Myasnikov, Alexander, Vinnikov, Ilya A., Margulis, Boris, Guzhova, Irina, Kagansky, Alexander, Konevega, Andrey L., Shtam, Tatiana

“…Plant-derived extracellular vesicles (EVs) gain more and more attention as promising carriers of exogenous bioactive molecules to the human cells. Derived from…”
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Dicer and microRNAs protect adult dopamine neurons by Chmielarz, Piotr, Konovalova, Julia, Najam, Syeda Sadia, Alter, Heike, Piepponen, Timo Petteri, Erfle, Holger, Sonntag, Kai C, Schütz, Günther, Vinnikov, Ilya A, Domanskyi, Andrii

“…MicroRNAs (miRs) are important post-transcriptional regulators of gene expression implicated in neuronal development, differentiation, aging and…”
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Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis by Isermann, Berend, Nawroth, Peter P, Bierhaus, Angelika, Herzog, Stefanie, Corat, Marcus A F, Weiler, Hartmut, Grinnell, Brian W, Kashif, Muhammed, Blautzik, Janusch, Berg, David T, Madhusudhan, Thati, Esmon, Charles T, Vinnikov, Ilya A, Blessing, Erwin, Oh, Jun, Zeier, Martin, Gerlitz, Bruce, Chavakis, Triantafyllos

“…Data providing direct evidence for a causative link between endothelial dysfunction, microvascular disease and diabetic end-organ damage are scarce. Here we…”
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Noodles, the all-in-one system for on-target efficiency analysis of CRISPR guide RNAs by Lin, Dongfa, Najam, Syeda Sadia, Liu, Yu, Murgia, Nicola, Vinnikov, Ilya A.

“…The efficiency of clustered regularly interspaced short palindromic repeats (CRISPR) guide RNA (gRNA) targeting is critical for CRISPR associated protein 9…”
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In Vivo Reductionist Approach Identifies miR-15a Protecting Mice From Obesity by Murgia, Nicola, Ma, Yuan, Najam, Syeda Sadia, Liu, Yu, Przybys, Joanna, Guo, Chenkai, Konopka, Witold, Vinnikov, Ilya A.

“…Obesity is a growing medical and social problem worldwide. The control of energy homeostasis in the brain is achieved by various regions including the arcuate…”
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Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance by Domanskyi, Andrii, Alter, Heike, Vogt, Miriam A, Gass, Peter, Vinnikov, Ilya A

“…The proteins Foxa1 and Foxa2 belong to the forkhead family of transcription factors and are involved in the development of several tissues, including liver,…”
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Neuronal miR-29a protects from obesity in adult mice by Ma, Yuan, Murgia, Nicola, Liu, Yu, Li, Zixuan, Sirakawin, Chaweewan, Konovalov, Ruslan, Kovzel, Nikolai, Xu, Yang, Kang, Xuejia, Tiwari, Anshul, Mwangi, Patrick Malonza, Sun, Donglei, Erfle, Holger, Konopka, Witold, Lai, Qingxuan, Najam, Syeda Sadia, Vinnikov, Ilya A.

“…Obesity, a growing threat to the modern society, represents an imbalance of metabolic queues that normally signal to the arcuate hypothalamic nucleus, a…”
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Can we treat neurodegenerative diseases by preventing an age-related decline in microRNA expression by Vinnikov, Ilya A, Domanskyi, Andrii

“…MicroRNA pathway is down-regulated in aged dopaminergic neurons： Parkinson＇s disease （PD） is the most frequent motor neuro- degenerative disorder and is…”
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Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy by Wang, Hongjie, Madhusudhan, Thati, He, Tao, Hummel, Björn, Schmidt, Simone, Vinnikov, Ilya A., Shahzad, Khurrum, Kashif, Muhammed, Muller-Krebs, Sandra, Schwenger, Vedat, Bierhaus, Angelika, Rudofsky, Gottfried, Nawroth, Peter P., Isermann, Berend

“…Whereas it is generally perceived to be harmful, enhanced coagulation activation can also convey salutary effects. The high prevalence of the prothrombotic…”
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Functional redundancy between glucocorticoid and mineralocorticoid receptors in mature corticotropin‐releasing hormone neurons protects from obesity by Liu, Yu, Lin, Dongfa, Najam, Syeda Sadia, Huang, Shangyuan, Song, Muyi, Sirakawin, Chaweewan, Zhao, Catherine, Jiang, Haixia, Konopka, Witold, Herzig, Stephan, Vinnikov, Ilya A.

“…Objective Here, we aimed to investigate the role of glucocorticoid and mineralocorticoid receptors (GRs and MRs, respectively) in the regulation of energy…”
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MicroRNAs in the hypothalamic control of energy homeostasis by Najam, Syeda Sadia, Zglinicki, Bartosz, Vinnikov, Ilya A., Konopka, Witold

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SKN‐1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans by Sirakawin, Chaweewan, Lin, Dongfa, Zhou, Ziyue, Wang, Xiaoxin, Kelleher, Rhianne, Huang, Shangyuan, Long, Weimiao, Pires‐daSilva, Andre, Liu, Yu, Wang, Jingjing, Vinnikov, Ilya A.

“…Vitamin A (VA) is a micronutrient essential for the physiology of many organisms, but its role in longevity and age‐related diseases remains unclear. In this…”
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Additional Cover by Sirakawin, Chaweewan, Lin, Dongfa, Zhou, Ziyue, Wang, Xiaoxin, Kelleher, Rhianne, Huang, Shangyuan, Long, Weimiao, Pires‐daSilva, Andre, Liu, Yu, Wang, Jingjing, Vinnikov, Ilya A.

“…Cover legend: The cover image is based on the Research Article SKN-1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for…”
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MicroRNAs are indispensable for the proliferation and differentiation of adult neural progenitor cells in mice by Xu, Yang, Hajdukiewicz, Karolina, Tiwari, Anshul, Przybyś, Joanna, Parkitna, Jan Rodriguez, Novak, Martin, Vinnikov, Ilya A., Schütz, Günther, Konopka, Witold

“…More than two decades after the discovery of adult neurogenesis in humans, researchers still struggle to elucidate the underlying transcriptional and…”
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Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models by Domanskyi, Andrii, Geiβler, Christin, Vinnikov, Ilya A., Alter, Heike, Schober, Andreas, Vogt, Miriam A., Gass, Peter, Parlato, Rosanna, Schütz, Günther

“…ABSTRACT Parkinson's disease (PD) is a progressive age‐related movement disorder that results primarily from the selective loss of midbrain dopaminergic (DA)…”
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Hypothalamic miR-103 protects from hyperphagic obesity in mice by Vinnikov, Ilya A, Hajdukiewicz, Karolina, Reymann, Jürgen, Beneke, Jürgen, Czajkowski, Rafal, Roth, Lena C, Novak, Martin, Roller, Andreas, Dörner, Nicole, Starkuviene, Vytaute, Theis, Fabian J, Erfle, Holger, Schütz, Günther, Grinevich, Valery, Konopka, Witold

“…The role of neuronal noncoding RNAs in energy control of the body is not fully understood. The arcuate nucleus (ARC) of the hypothalamus comprises neurons…”
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Purification of filamentous bacteriophage for phage display using size-exclusion chromatography by Zakharova, Maria Yu, Kozyr, Arina V, Ignatova, Anna N, Vinnikov, Ilya A, Shemyakin, Igor G, Kolesnikov, Alexander V

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Hypercoagulability Inhibits Monocyte Transendothelial Migration Through Protease-Activated Receptor-1-, Phospholipase-Cβ-, Phosphoinositide 3-Kinase-, and Nitric Oxide-Dependent Signaling in Monocytes and Promotes Plaque Stability by SEEHAUS, Stefanie, SHAHZAD, Khurrum, BLESSING, Erwin, WEILER, Hartmut, FROMMHOLD, David, NAWROTH, Peter P, ISERMANN, Berend, KASHIF, Muhammed, VINNIKOV, Ilya A, SCHILLER, Martin, HONGJIE WANG, MADHUSUDHAN, Thati, ECKSTEIN, Volker, BIERHAUS, Angelika, BEA, Florian

“…Background— Clinical studies failed to provide clear evidence for a proatherogenic role of hypercoagulability. This is in contrast to the well-established…”
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Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability by Seehaus, Stefanie, Shahzad, Khurrum, Kashif, Muhammed, Vinnikov, Ilya A, Schiller, Martin, Wang, Hongjie, Madhusudhan, Thati, Eckstein, Volker, Bierhaus, Angelika, Bea, Florian, Blessing, Erwin, Weiler, Hartmut, Frommhold, David, Nawroth, Peter P, Isermann, Berend

“…Clinical studies failed to provide clear evidence for a proatherogenic role of hypercoagulability. This is in contrast to the well-established detrimental role…”
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