Search Results - "Vink, Hans"

Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis by Rovas, Alexandros, Seidel, Laura Mareen, Vink, Hans, Pohlkötter, Timo, Pavenstädt, Hermann, Ertmer, Christian, Hessler, Michael, Kümpers, Philipp

“…The endothelial glycocalyx (eGC) covers the luminal surface of the vascular endothelium and plays an important protective role in systemic inflammatory states…”
Get full text

Microvascular dysfunction in COVID-19: the MYSTIC study by Rovas, Alexandros, Osiaevi, Irina, Buscher, Konrad, Sackarnd, Jan, Tepasse, Phil-Robin, Fobker, Manfred, Kühn, Joachim, Braune, Stephan, Göbel, Ulrich, Thölking, Gerold, Gröschel, Andreas, Pavenstädt, Hermann, Vink, Hans, Kümpers, Philipp

“…Rationale Pre-clinical and autopsy studies have fueled the hypothesis that a dysregulated vascular endothelium might play a central role in the pathogenesis of…”
Get full text

Identification of novel sublingual parameters to analyze and diagnose microvascular dysfunction in sepsis: the NOSTRADAMUS study by Rovas, Alexandros, Sackarnd, Jan, Rossaint, Jan, Kampmeier, Stefanie, Pavenstädt, Hermann, Vink, Hans, Kümpers, Philipp

“…The availability of handheld, noninvasive sublingual video-microscopes allows for visualization of the microcirculation in critically ill patients. Recent…”
Get full text

Damage of the Endothelial Glycocalyx in Dialysis Patients by VLAHU, Carmen A, LEMKES, Bregtje A, STRUIJK, Dirk G, KOOPMAN, Marion G, KREDIET, Raymond T, VINK, Hans

“…Damage to the endothelial glycocalyx, which helps maintain vascular homeostasis, heightens the sensitivity of the vasculature to atherogenic stimuli. Patients…”
Get full text

Uncoupling of Microvascular Blood Flow and Capillary Density in Vascular Cognitive Impairment by Zhang, Chenxing Eleana, Staals, Julie, van Oostenbrugge, Robert Jan, Vink, Hans

“…Cerebral small vessel disease (cSVD) plays an important role in dementia and is a major cause for vascular cognitive impairment (VCI). Recent studies…”
Get full text

The endothelial glycocalyx: composition, functions, and visualization by Reitsma, Sietze, Slaaf, Dick W, Vink, Hans, van Zandvoort, Marc A M J, oude Egbrink, Mirjam G A

“…This review aims at presenting state-of-the-art knowledge on the composition and functions of the endothelial glycocalyx. The endothelial glycocalyx is a…”
Get full text

Bedside analysis of the sublingual microvascular glycocalyx in the emergency room and intensive care unit - the GlycoNurse study by Rovas, Alexandros, Lukasz, Alexander-Henrik, Vink, Hans, Urban, Marc, Sackarnd, Jan, Pavenstädt, Hermann, Kümpers, Philipp

“…Deterioration of the endothelial glycocalyx (eGC), a protective carbohydrate-rich layer lining the luminal surface of the endothelium, plays a key role in…”
Get full text

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium by van den Berg, Bernard M, Wang, Gangqi, Boels, Margien G S, Avramut, M Cristina, Jansen, Erik, Sol, Wendy M P J, Lebrin, Franck, van Zonneveld, Anton Jan, de Koning, Eelco J P, Vink, Hans, Gröne, Hermann-Josef, Carmeliet, Peter, van der Vlag, Johan, Rabelink, Ton J

“…A glycocalyx envelope consisting of proteoglycans and adhering proteins covers endothelial cells, both the luminal and abluminal surface. We previously…”
Get full text

Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion by Lee, Dae Hyun, Dane, Martijn J C, van den Berg, Bernard M, Boels, Margien G S, van Teeffelen, Jurgen W, de Mutsert, Renée, den Heijer, Martin, Rosendaal, Frits R, van der Vlag, Johan, van Zonneveld, Anton Jan, Vink, Hans, Rabelink, Ton J

“…Changes in endothelial glycocalyx are one of the earliest changes in development of cardiovascular disease. The endothelial glycocalyx is both an important…”
Get full text

A microscopic view on the renal endothelial glycocalyx by Dane, Martijn J C, van den Berg, Bernard M, Lee, Dae Hyun, Boels, Margien G S, Tiemeier, Gesa L, Avramut, M Cristina, van Zonneveld, Anton Jan, van der Vlag, Johan, Vink, Hans, Rabelink, Ton J

“…Endothelial cells perform key homeostatic functions such as regulating blood flow, permeability, and aiding immune surveillance for pathogens. While…”
Get more information

Sublingual microvascular glycocalyx dimensions in lacunar stroke patients by Martens, Remy J H, Vink, Hans, van Oostenbrugge, Robert J, Staals, Julie

“…Cerebral small vessel disease is thought to result from endothelial dysfunction. The glycocalyx, lining the endothelium, is a major determinant of endothelial…”
Get more information

Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia by Wijnands, Karolina A P, Vink, Hans, Briedé, Jacob J, van Faassen, Ernst E, Lamers, Wouter H, Buurman, Wim A, Poeze, Martijn

“…Impaired microcirculation during endotoxemia correlates with a disturbed arginine-nitric oxide (NO) metabolism and is associated with deteriorating organ…”
Get full text

Mechanotransduction and Flow across the Endothelial Glycocalyx by Weinbaum, Sheldon, Zhang, Xiaobing, Han, Yuefeng, Vink, Hans, Cowin, Stephen C.

“…In this inaugural paper, we shall provide an overview of the endothelial surface layer or glycocalyx in several roles: as a transport barrier, as a porous…”
Get full text

A Dietary Supplement Containing Fucoidan Preserves Endothelial Glycocalyx through ERK/MAPK Signaling and Protects against Damage Induced by CKD Serum by Regier, Manuel, Drost, Carolin Christina, Rauen, Matthias, Pavenstädt, Hermann, Rovas, Alexandros, Kümpers, Philipp, Vink, Hans, Long, Robert M, Linke, Wolfgang A, Nofer, Jerzy-Roch, Lukasz, Alexander-Henrik

“…(1) Damage to the endothelial glycocalyx (eGC), a protective layer lining the endothelial luminal surface, is associated with chronic kidney disease (CKD),…”
Get full text

The Effect of 4-Month Treatment with Glycocalyx Dietary Supplement on Endothelial Glycocalyx Integrity and Vascular Function in Patients with Psoriasis by Ikonomidis, Ignatios, Katsanaki, Eleni, Thymis, John, Pavlidis, George, Lampadaki, Kyriaki, Katogiannis, Konstantinos, Vaiopoulos, Aristeidis, Lazarou, Vicky, Kostelli, Gavriella, Michalopoulou, Eleni, Pililis, Sotirios, Vlachomitros, Dimitrios, Theodoropoulos, Konstantinos, Vink, Hans, Long, Robert, Papadavid, Evangelia, Lambadiari, Vaia

“…Psoriasis predisposes to cardiovascular dysfunction. We investigated whether glycocalyx dietary supplement (GDS), which contains glycosaminoglycans and…”
Get full text

Glomerular Endothelial Surface Layer Acts as a Barrier against Albumin Filtration by Dane, Martijn J.C, van den Berg, Bernard M, Avramut, M. Cristina, Faas, Frank G.A, van der Vlag, Johan, Rops, Angelique L.W.M.M, Ravelli, Raimond B.G, Koster, Bram J, van Zonneveld, Anton Jan, Vink, Hans, Rabelink, Ton J

“…Glomerular endothelium is highly fenestrated, and its contribution to glomerular barrier function is the subject of debate. In recent years, a…”
Get full text

Impaired glycocalyx barrier properties contribute to enhanced intimal low-density lipoprotein accumulation at the carotid artery bifurcation in mice by van den Berg, Bernard M., Spaan, Jos A. E., Vink, Hans

“…The glycocalyx contributes to the barrier properties of vascular endothelium, and recently, we reported using electron microscopy that glycocalyx is diminished…”
Get full text

Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability by Nieuwdorp, Max, Meuwese, Marijn C, Mooij, Hans L, Ince, Can, Broekhuizen, Lysette N, Kastelein, John J. P, Stroes, Erik S. G, Vink, Hans

“…Departments of 1 Vascular Medicine and of 2 Physiology, Academic Medical Center, Amsterdam; and 3 Department of Physiology, Maastricht University, Maastricht,…”
Get full text

Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes by NIEUWDORP, Max, MOOIJ, Hans L, KASTELEIN, John J. P, STROES, Erik S. G, VINK, Hans, KROON, Jojanneke, ATASEVER, Bektas, SPAAN, Jos A. E, INCE, Can, HOLLEMAN, Frits, DIAMANT, Michaela, HEINE, Robert J, HOEKSTRA, Joost B. L

“…Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes Max Nieuwdorp 1 , Hans L. Mooij 1 , Jojanneke Kroon 1 , Bektas Atasever 2 ,…”
Get full text

Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo by NIEUWDORP, Max, VAN HAEFTEN, Timon W, KASTELEIN, John J. P, STROES, Erik S. G, GOUVERNEUR, Mirella C. L. G, MOOIJ, Hans L, VAN LIESHOUT, Miriam H. P, LEVI, Marcel, MEIJERS, Joost C. M, HOLLEMAN, Frits, HOEKSTRA, Joost B. L, VINK, Hans

“…Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo Max Nieuwdorp 1 , Timon W…”
Get full text