Search Results - "Vink, Arie A."

Enzyme Plus Light Therapy to Repair DNA Damage in Ultraviolet-B-Irradiated Human Skin by Stege, Helger, Roza, Len, Vink, Arie A., Grewe, Markus, Ruzicka, Thomas, Grether-Beck, Susanne, Krutmann, Jean

“…Ultraviolet-B (UVB) (290-320 nm) radiation-induced cyclobutane pyrimidine dimers within the DNA of epidermal cells are detrimental to human health by causing…”
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Mechanisms Underlying the Suppression of Established Immune Responses by Ultraviolet Radiation by Nghiem, Dat X., Kazimi, Nasser, Mitchell, David L., Vink, Arie A., Ananthaswamy, Honnavara N., Kripke, Margaret L., Ullrich, Stephen E.

“…The ultraviolet radiation present in sunlight is immune suppressive. Recently we showed that solar-simulated ultraviolet radiation (ultraviolet A + B; 295–400…”
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Biological consequences of cyclobutane pyrimidine dimers by Vink, Arie A, Roza, Len

“…In the skin many molecules may absorb ultraviolet (UV) radiation upon exposure. In particular, cellular DNA strongly absorbs shorter wavelength solar UV…”
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Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers by Rhodes, Lesley E., Shahbakhti, Hassan, Azurdia, Richard M., Moison, Ralf M.W., Steenwinkel, Marie-Jose S.T., Homburg, Marie I., Dean, Michael P., McArdle, F., Beijersbergen van Henegouwen, Gerard M.J., Epe, Bernd, Vink, Arie A.

“…Dietary omega-3 polyunsaturated fatty acids (ω-3 PUFAs) protect against photocarcinogenesis in animals, but prospective human studies are scarce. The…”
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Evidence that DNA Damage Triggers Interleukin 10 Cytokine Production in UV-Irradiated Murine Keratinocytes by Nishigori, Chikako, Yarosh, Daniel B., Ullrich, Stephen E., Vink, Arie A., Bucana, Corazon D., Roza, Len, Kripke, Margaret L.

“…UV irradiation interferes with the induction of T cell-mediated immune responses, in part by causing cells in the skin to produce immunoregulatory cytokines…”
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The inhibition of Antigen-Presenting Activity of Dendritic Cells Resulting from UV Irradiation of Murine Skin is Restored by in vitro Photorepair of Cyclobutane Pyrimidine Dimers by Vink, Arie A., Moodycliffe, Angus M., Shreedhar, Vijay, Ullrich, Stephen E., Roza, Len, Yarosh, Danile B., Kripke, Margaret L.

“…Exposing skin to UVB (280-320 nm) radiation suppresses contact hypersensitivity by a mechanism that involves an alteration in the activity of cutaneous…”
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Attenuation of Biologically Effective UV Radiation in Tropical Atlantic Waters Measured with a Biochemical DNA Dosimeter by Boelen, Peter, Obernostere, Ingrid, Vink, Arie A., Buma, Anita G. J.

“…— A biochemical dosimeter was developed to study the attenuation of biologically effective UV radiation in marine tropical waters. Small quartz vials were used…”
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Chromophore for UV-induced immunosuppression: DNA by Vink, A A, Yarosh, D B, Kripke, M L

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A role for NF-κB–dependent gene transactivation in sunburn by Abeyama, Kazuhiro, Eng, William, Jester, James V., Vink, Arie A., Edelbaum, Dale, Cockerell, Clay J., Bergstresser, Paul R., Takashima, Akira

“…Exposure of skin to ultraviolet (UV) radiation is known to induce NF-κB activation, but the functional role for this pathway in UV-induced cutaneous…”
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Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice by Vink, A A, Strickland, F M, Bucana, C, Cox, P A, Roza, L, Yarosh, D B, Kripke, M L

“…Prior ultraviolet (UV) irradiation of the site of application of hapten on murine skin reduces contact sensitization, impairs the ability of dendritic cells in…”
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Cellular target of UVB-induced DNA damage resulting in local suppression of contact hypersensitivity by Vink, Arie A., Shreedhar, Vijay, Roza, L., Krutmann, Jean, Kripke, Margaret L.

“…Experimental data are reviewed that lend support to the hypothesis that formation of DNA damage is the initiation event of local suppression of contact…”
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Cells with UV-Specific DNA Damage Are Present in Murine Lymph Nodes After In Vivo UV Irradiation by Sontag, Yvonne, Guikers, Cees L H, Vink, Arie A, de Gruijl, Frank R, van Loveren, Henk, Garssen, Johan, Roza, L.e.n., Kripke, Margaret L, van der Leun, Jan C, van Vloten, Willem A

“…Ultraviolet radiation is absorbed in the skin, especially in the epidermis. After ultraviolet irradiation the number of major histocompatibility complex class…”
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The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored by in vitro photorepair of cyclobutane pyrimiding dimers by Vink, Arie A, Moodycliffe, Angus M, Shreedhar, Vijay, Ullrich, Stephen E

“…Research results provide compelling evidence that ultraviolet-induced DNA damage in cutaneous antigen-presenting cells leads to reduced immune function in mice…”
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Removal of UV-induced DNA lesions in mouse epidermis soon after irradiation by Vink, A A, Henegouwen, B, Nikaido, O, Baan, R A, Roza, L

“…Induction and removal of cyclobutane thymine dimers and (6-4)photoproducts were studied in epidermal DNA isolated from UV-exposed hairless mice. For the…”
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Rôle of DNA damage in local suppression of contact hypersensitivity in mice by UV radiation by Kripke, M L, Cox, P A, Bucana, C, Vink, A A, Alas, L, Yarosh, D B

“…Exposure of mice to UVB radiation down-regulates the induction of contact hypersensitivity (CHS) responses to haptens applied to the site of irradiation…”
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The mechanism of N-acetylcysteine photoprotection is not related to dipyrimidine photoproducts by Nijmeijer, Bart A., Steenvoorden, David P.T., Beijersbergen van Henegouwen, Gerard M.J., Roza, Len, Vink, Arie A.

“…Topical application of N-acetylcysteine prior to UVB irradiation of BALB/c mice has previously been shown to inhibit systemic suppression of the contact…”
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Detection of Thymine Dimers in Suprabasal and Basal Cells of Chronically UV-B Exposed Hairless Mice by Vink, Arie A., Berg, Rob J.W., de Gruijl, Frank R., Lohman, Paul H.M., Roza, Len, Baan, Robert A.

“…An immunocytochemical method was developed to study induction and removal of DNA damage in specific cell populations in the epidermis of hairless mice during…”
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