Search Results - "Vinicius de Lima Vazquez"
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Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation
Published in Pharmacological research (01-09-2016)“…[Display omitted] The BRAFV600E mutation confers constitutive kinase activity and accounts for >90% of BRAF mutations in melanoma. This genetic alteration is a…”
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2
Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure
Published in Nature communications (15-07-2022)“…Ultraviolet radiation (UV) is causally linked to cutaneous melanoma, yet the underlying epigenetic mechanisms, known as molecular sensors of exposure, have not…”
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3
Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line
Published in Human cell : official journal of Human Cell Research Society (2024)“…Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer that can result in significant morbidity, although it is usually well-managed and…”
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4
Circulating tumor DNA (ctDNA) detection is associated with shorter progression-free survival in advanced melanoma patients
Published in Scientific reports (29-10-2020)“…BRAF , NRAS and TERT mutations occur in more than 2/3 of melanomas. Its detection in patient’s blood, as circulating tumor DNA (ctDNA), represents a…”
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5
Association of Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Genetic Variants with Risk and Outcome of Cutaneous Melanoma
Published in International journal of molecular sciences (17-11-2024)“…This study aimed to verify whether germline single nucleotide variants (SNV) in CTLA-4 gene, c.-1765C>T, c.-1661A>G, c.-1577G>A, and c.-1478G>A, influence the…”
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6
Clinical characterization of the Dermatofibrosarcomas at Barretos Cancer Hospital in São Paulo
Published in Brazilian Journal of Oncology (01-12-2022)“…Introduction: Dermatofibrosarcoma (DFSP) is a rare neoplasia from mesenchymal tissues in the skin. It has a high potential for local invasion and a high rate…”
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7
PD-1/PD-L1 and VEGF-A/VEGF-C expression in lymph node microenvironment and association with melanoma metastasis and survival
Published in Melanoma research (01-12-2017)“…Regional lymph nodes are affected frequently by melanoma metastasis. Its microenvironment may be associated with tumor progression. We investigated sentinel…”
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8
TNFRSF1B Gene Variants in Clinicopathological Aspects and Prognosis of Patients with Cutaneous Melanoma
Published in International journal of molecular sciences (01-03-2024)“…Regulatory T lymphocytes play a critical role in immune regulation and are involved in the aberrant cell elimination by facilitating tumor necrosis factor…”
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9
Indoleamine 2,3-dioxygenase in melanoma progression and BRAF inhibitor resistance
Published in Pharmacological research (01-09-2020)“…[Display omitted] Indoleamine 2,3-dioxygenase (IDO) is associated with the progression of many types of tumors, including melanoma. However, there is limited…”
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10
Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities
Published in World journal of surgical oncology (04-07-2008)“…Squamous cell carcinoma (SCC) of the skin of the trunk and extremities may present lymph node metastasis with difficult disease control and poor survival. The…”
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11
Brazilian Society of Surgical Oncology recommendations on Merkel cell carcinoma surgical treatment
Published in Journal of surgical oncology (01-09-2024)“…Background Merkel cell carcinoma (MCC) is a rare neuroendocrine skin cancer with poor 5‐year survival rates. Surgery and radiation are the current first‐line…”
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12
Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas
Published in Melanoma research (01-04-2016)“…Acral lentiginous melanoma (ALM) is the less common subtype with singular characterization. TERT (human telomerase reverse transcriptase) promoter mutations…”
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13
PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil
Published in Diagnostics (Basel) (01-03-2023)“…Immune checkpoint blockade (ICB) agents are prominent immunotherapies for the treatment of advanced melanoma. However, they fail to promote any durable…”
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14
TNFRSF1B GENE VARIANTS IN RISK AND CLINICOPATHOLOGICAL ASPECTS OF PATIENTS WITH CUTANEOUS MELANOMA
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: Cutaneous melanoma (CM) is a low incidence tumor worldwide but is associated with high mortality. Skin exposure to ultraviolet…”
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15
Sociodemographic effect on stage at diagnosis of melanoma patients treated in a public cancer center in Brazil
Published in Brazilian Journal of Oncology (01-10-2023)“…INTRODUCTION: Melanoma is the most aggressive type of skin cancer, with a continuous increase in its incidence worldwide. The prognosis of patients is…”
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16
Characteristics of Brazilian melanomas: real-world results before and after the introduction of new therapies
Published in BMC research notes (28-05-2019)“…This study is a characterization of the treatment patterns and outcomes of a Brazilian melanoma cohort collected of 1848 patients enrolled between 1996 and…”
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17
Xiphoidectomy
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-06-2003)“…Complex surgical procedures in the upper abdomen required ear exposure. To improve exposure xiphoidectomy is indicated; however, in the past there was an…”
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18
Demographic, Clinical, and Pathologic Features of Patients With Cutaneous Melanoma: Final Analysis of the Brazilian Melanoma Group Database
Published in JCO global oncology (01-04-2020)“…National epidemiologic data on melanoma are scarce in Brazil. The current work presents final demographic, clinical, and pathologic results from the Brazilian…”
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19
Extent of parietal peritonectomy does not change intraperitoneal chemotherapy pharmacokinetics
Published in Cancer chemotherapy and pharmacology (01-08-2003)“…To measure the clearance intraperitoneal mitomycin C and doxorubicin in patients having peritonectomy and analyze the impact of the extent of peritoneal…”
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Total anterior parietal peritonectomy
Published in Journal of surgical oncology (01-08-2003)Get full text
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