Search Results - "Vinckier, Nicholas K."

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors by Geusz, Ryan J., Wang, Allen, Lam, Dieter K., Vinckier, Nicholas K., Alysandratos, Konstantinos-Dionysios, Roberts, David A., Wang, Jinzhao, Kefalopoulou, Samy, Ramirez, Araceli, Qiu, Yunjiang, Chiou, Joshua, Gaulton, Kyle J., Ren, Bing, Kotton, Darrell N., Sander, Maike

“…FOXA pioneer transcription factors (TFs) associate with primed enhancers in endodermal organ precursors. Using a human stem cell model of pancreas…”
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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development by Vinckier, Nicholas K., Patel, Nisha A., Geusz, Ryan J., Wang, Allen, Wang, Jinzhao, Matta, Ileana, Harrington, Austin R., Wortham, Matthew, Wetton, Nichole, Wang, Jianxun, Jhala, Ulupi S., Rosenfeld, Michael G., Benner, Christopher W., Shih, Hung-Ping, Sander, Maike

“…Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the…”
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Nutrient regulation of the islet epigenome controls adaptive insulin secretion by Wortham, Matthew, Liu, Fenfen, Harrington, Austin R, Fleischman, Johanna Y, Wallace, Martina, Mulas, Francesca, Mallick, Medhavi, Vinckier, Nicholas K, Cross, Benjamin R, Chiou, Joshua, Patel, Nisha A, Sui, Yinghui, McGrail, Carolyn, Jun, Yesl, Wang, Gaowei, Jhala, Ulupi S, Schüle, Roland, Shirihai, Orian S, Huising, Mark O, Gaulton, Kyle J, Metallo, Christian M, Sander, Maike

“…Adaptation of the islet β cell insulin-secretory response to changing insulin demand is critical for blood glucose homeostasis, yet the mechanisms underlying…”
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Improved isolation of proteins tagged with glutathione S-transferase by Vinckier, Nicholas K., Chworos, Arkadiusz, Parsons, Stanley M.

“…A common affinity tag used to express and purify fusion proteins is glutathione S-transferase. However, many researchers have reported difficulty eluting…”
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