Search Results - "Vincent, Catherine E."

Blood DNA methylation and COVID-19 outcomes by Balnis, Joseph, Madrid, Andy, Hogan, Kirk J, Drake, Lisa A, Chieng, Hau C, Tiwari, Anupama, Vincent, Catherine E, Chopra, Amit, Vincent, Peter A, Robek, Michael D, Singer, Harold A, Alisch, Reid S, Jaitovich, Ariel

“…There are no prior reports that compare differentially methylated regions of DNA in blood samples from COVID-19 patients to samples collected before the…”
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Defining mitochondrial protein functions through deep multiomic profiling by Rensvold, Jarred W., Shishkova, Evgenia, Sverchkov, Yuriy, Miller, Ian J., Cetinkaya, Arda, Pyle, Angela, Manicki, Mateusz, Brademan, Dain R., Alanay, Yasemin, Raiman, Julian, Jochem, Adam, Hutchins, Paul D., Peters, Sean R., Linke, Vanessa, Overmyer, Katherine A., Salome, Austin Z., Hebert, Alexander S., Vincent, Catherine E., Kwiecien, Nicholas W., Rush, Matthew J. P., Westphall, Michael S., Craven, Mark, Akarsu, Nurten A., Taylor, Robert W., Coon, Joshua J., Pagliarini, David J.

“…Mitochondria are epicentres of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of…”
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High CO2 Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2–mediated Depressed Ribosomal Biogenesis by Korponay, Tanner C, Balnis, Joseph, Vincent, Catherine E, Singer, Diane V, Chopra, Amit, Adam, Alejandro P, Ginnan, Roman, Singer, Harold A, Jaitovich, Ariel

“…High CO2 retention, or hypercapnia, is associated with worse outcomes in patients with chronic pulmonary diseases. Skeletal muscle wasting is also an…”
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Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy by Stefely, Jonathan A., Zhang, Yu, Freiberger, Elyse C., Kwiecien, Nicholas W., Thomas, Hala Elnakat, Davis, Alexander M., Lowry, Nathaniel D., Vincent, Catherine E., Shishkova, Evgenia, Clark, Nicholas A., Medvedovic, Mario, Coon, Joshua J., Pagliarini, David J., Mercer, Carol A.

“…Macroautophagy/autophagy is suppressed by MTOR (mechanistic target of rapamycin kinase) and is an anticancer target under active investigation. Yet,…”
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Deaccelerated Myogenesis and Autophagy in Genetically Induced Pulmonary Emphysema by Balnis, Joseph, Drake, Lisa A, Singer, Diane V, Vincent, Catherine E, Korponay, Tanner C, D'Armiento, Jeanine, Lee, Chun Geun, Elias, Jack A, Singer, Harold A, Jaitovich, Ariel

“…Patients with chronic obstructive pulmonary disease (COPD)-pulmonary emphysema often develop locomotor muscle dysfunction, which entails reduced muscle mass…”
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SDH Subunit C Regulates Muscle Oxygen Consumption and Fatigability in an Animal Model of Pulmonary Emphysema by Balnis, Joseph, Drake, Lisa A, Vincent, Catherine E, Korponay, Tanner C, Singer, Diane V, Lacomis, David, Lee, Chun Geun, Elias, Jack A, Jourd'heuil, David, Singer, Harold A, Jaitovich, Ariel

“…Patients with pulmonary emphysema often develop locomotor muscle dysfunction, which is independently associated with disability and higher mortality in that…”
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IL-13-driven pulmonary emphysema leads to skeletal muscle dysfunction attenuated by endurance exercise by Balnis, Joseph, Korponay, Tanner C, Vincent, Catherine E, Singer, Diane V, Adam, Alejandro P, Lacomis, David, Lee, Chun Geun, Elias, Jack A, Singer, Harold A, Jaitovich, Ariel

“…Patients with chronic obstructive pulmonary disease (COPD) usually develop skeletal muscle dysfunction, which represents a major comorbidity in these patients…”
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Established Biomarkers of Chronic Obstructive Pulmonary Disease Reflect Skeletal Muscle Integrity’s Response to Exercise in an Animal Model of Pulmonary Emphysema by Balnis, Joseph, Vincent, Catherine E., Jones, Alyssa J., Drake, Lisa A., Coon, Joshua J., Lee, Chun Geun, Elias, Jack A., Singer, Harold A., Jaitovich, Ariel

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High CO 2 Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2-mediated Depressed Ribosomal Biogenesis by Korponay, Tanner C, Balnis, Joseph, Vincent, Catherine E, Singer, Diane V, Chopra, Amit, Adam, Alejandro P, Ginnan, Roman, Singer, Harold A, Jaitovich, Ariel

“…High CO retention, or hypercapnia, is associated with worse outcomes in patients with chronic pulmonary diseases. Skeletal muscle wasting is also an…”
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Succinate dehydrogenase-complex II regulates skeletal muscle cellular respiration and contractility but not muscle mass in genetically induced pulmonary emphysema by Balnis, Joseph, Tufts, Ankita, Jackson, Emily L, Drake, Lisa A, Singer, Diane V, Lacomis, David, Lee, Chun Geun, Elias, Jack A, Doles, Jason D, Maher, 3rd, L James, Jen, Annie, Coon, Joshua J, Jourd'heuil, David, Singer, Harold A, Vincent, Catherine E, Jaitovich, Ariel

“…Reduced skeletal muscle mass and oxidative capacity coexist in patients with pulmonary emphysema and are independently associated with higher mortality. If…”
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Neutron-encoded Signatures Enable Product Ion Annotation From Tandem Mass Spectra by Richards, Alicia L., Vincent, Catherine E., Guthals, Adrian, Rose, Christopher M., Westphall, Michael S., Bandeira, Nuno, Coon, Joshua J.

“…We report the use of neutron-encoded (NeuCode) stable isotope labeling of amino acids in cell culture for the purpose of C-terminal product ion annotation. Two…”
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Automated Gas-Phase Purification for Accurate, Multiplexed Quantification on a Stand-Alone Ion-Trap Mass Spectrometer by Vincent, Catherine E, Rensvold, Jarred W, Westphall, Michael S, Pagliarini, David J, Coon, Joshua J

“…Isobaric tagging enables the acquisition of highly multiplexed proteome quantification, but it is hindered by the pervasive problem of precursor interference…”
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Segmentation of Precursor Mass Range Using “Tiling” Approach Increases Peptide Identifications for MS1‑Based Label-Free Quantification by Vincent, Catherine E, Potts, Gregory K, Ulbrich, Arne, Westphall, Michael S, Atwood, James A, Coon, Joshua J, Weatherly, D. Brent

“…Label-free quantification is a powerful tool for the measurement of protein abundances by mass spectrometric methods. To maximize quantifiable identifications,…”
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Use of Mass Spectrometry‐Based Proteomics to Investigate Protein Regulation Associated with COPD‐Related Muscle Dysfunction by Schiltz, Sarah B., Balnis, Joseph, Jaitovich, Ariel, Vincent, Catherine E.

“…Abstract only Chronic Obstructive Pulmonary Disease (COPD) is an umbrella term used to encompass several progressive lung diseases. A common comorbidity of…”
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2569. Pharmacokinetic-Pharmacodynamic Evaluation of Sulopenem Using a Five-Day Hollow-Fiber In Vitro Infection Model by VanScoy, Brian D, Conde, Haley, Vincent, Catherine E, Bhavnani, Sujata M, Aronin, Steven I, Puttagunta, Sailaja, Ambrose, Paul G

“…Abstract Background Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem, is a thiopenem in development for the treatment of…”
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Defining mitochondrial protein functions through deep multi-omic profiling by Rensvold, Jarred W., Shishkova, Evgenia, Sverchkov, Yuriy, Miller, Ian J., Cetinkaya, Arda, Pyle, Angela, Manicki, Mateusz, Brademan, Dain R., Alanay, Yasemin, Raiman, Julian, Jochem, Adam, Hutchins, Paul D., Peters, Sean R., Linke, Vanessa, Overmyer, Katherine A., Salome, Austin Z., Hebert, Alexander S., Vincent, Catherine E., Kwiecien, Nicholas W., Rush, Matthew J.P., Westphall, Michael S., Craven, Mark, Akarsu, Nurten A., Taylor, Robert W., Coon, Joshua J., Pagliarini, David J.

“…Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of…”
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2568. Characterization of Sulopenem Pharmacokinetics-Pharmacodynamics Using a One-Compartment In Vitro Infection Model by VanScoy, Brian D, Jones, Sean, Conde, Haley, Vincent, Catherine E, Bhavnani, Sujata M, Rubino, Christopher M, Aronin, Steven I, Puttagunta, Sailaja, Ambrose, Paul G

“…Abstract Background Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem is a thiopenem with activity against drug-resistant pathogens…”
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Segmentation of Precursor Mass Range Using "Tiling" Approach Increases Peptide Identifications for MS^sup 1^-Based Label-Free Quantification by Vincent, Catherine E, Potts, Gregory K, Ulbrich, Arne, Westphall, Michael S, Atwood, James A, Coon, Joshua J, Weatherly, D Brent

“…Label-free quantification is a powerful tool for the measurement of protein abundances by mass spectrometric methods. To maximize quantifiable identifications,…”
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Segmentation of Precursor Mass Range Using “Tiling” Approach Increases Peptide Identifications for MS 1 -Based Label-Free Quantification by Vincent, Catherine E., Potts, Gregory K., Ulbrich, Arne, Westphall, Michael S., Atwood, James A., Coon, Joshua J., Weatherly, D. Brent

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