Search Results - "Vinayaka, Ajjampura C"
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Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
Published in Scientific reports (14-01-2021)“…Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. This study intended to examine the anti-inflammatory activity of…”
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Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization
Published in Molecules (Basel, Switzerland) (17-01-2021)“…contains more than 500 constituents, yet the anticancer properties of the vast majority of cannabis compounds remains unknown. We aimed to identify cannabis…”
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Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Ovarian cancer (OC) is the single most lethal gynecologic malignancy. Cannabis sativa is used to treat various medical conditions, and is cytotoxic to a…”
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Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2022)“…Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD],…”
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IPSO-Hydroxylation of Boronic Acid via Ozonolysis: A Metal-, Ligand-, and Base-free Method
Published in Chemistry letters (05-03-2016)“…Here, we have developed a simple, efficient, and metal-, ligand-, and base-free method for the synthesis of functionalized aryl and alicyclic alcohols via…”
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A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis
Published in PloS one (19-09-2014)“…Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease,…”
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Facile synthesis of antimalarial 1,2-disubstituted 4-quinolones from 1,3-bisaryl-monothio-1,3-diketones
Published in Organic & biomolecular chemistry (14-11-2014)“…A new strategy was developed to synthesize 1,2-disubstituted 4-quinolones in good yield starting from 1,3-bisaryl-monothio-1,3-diketone substrates. The…”
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Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro
Published in Cancers (05-04-2021)“…Glioblastoma multiforme (GBM) is the most lethal subtype of glioma. is used for the treatment of various medical conditions. Around 150 phytocannabinoids have…”
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Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo
Published in Oncotarget (31-03-2020)“…produces hundreds of phytocannabinoids and terpenes. Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), characterized by…”
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Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi-Substituted Δ 2 -Pyrrolines and Their Cytotoxicity
Published in Chemistry & biodiversity (01-05-2020)“…An efficient, metal free approach to synthesize multi-substituted Δ -pyrroline derivatives by mild base catalyzed cyclocondensation of malononitrile with…”
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Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi‐Substituted Δ2‐Pyrrolines and Their Cytotoxicity
Published in Chemistry & biodiversity (01-05-2020)“…An efficient, metal free approach to synthesize multi‐substituted Δ2‐pyrroline derivatives by mild base catalyzed cyclocondensation of malononitrile with…”
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Aqueous Chloroplatinic Acid: A Green, Chemoselective and Reusable Catalyst for the Deprotection of Acetals, Ketals, Dioxolanes and Oxathiolanes
Published in ChemistrySelect (Weinheim) (21-02-2018)“…Aqueous chloroplatinic acid (H2PtCl6) as an effective catalyst for the deprotection of acetals, ketals, 1,3‐dioxolanes and 1,3‐oxathiolanes to the…”
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13
IPSO-Hydroxylation of Boronic Acid via Ozonolysis
Published in Chemistry letters (01-03-2016)“…Here, we have developed a simple, efficient, and metal-, ligand-, and base-free method for the synthesis of functionalized aryl and alicyclic alcohols via…”
Get full text
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