Human papillomavirus infection prevalence in female university students in Novi Sad, Serbia
Cervical cancer, attributed to human papillomavirus (HPV) infection, represents the fourth most common and lethal cancer in Serbian women, and the second most common cancer in women aged 15–44. The aim of the study was to determine the presence of high-risk and low-risk HPV types in population of un...
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| Published in: | Srpski arhiv za celokupno lekarstvo Vol. 144; no. 5-6; pp. 300 - 306 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Serbia
Serbian Medical Society
01-05-2016
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Cervical cancer, attributed to human papillomavirus (HPV) infection, represents the fourth
most common and lethal cancer in Serbian women, and the second most common cancer in women
aged 15–44.
The aim of the study was to determine the presence of high-risk and low-risk HPV types in
population of unvaccinated female university students in Novi Sad, Serbia, and to evaluate possible risk
factors for HPV infection.
Sample consisted of 250 young women (19–26 years of age) attending outpatient clinics for
screening gynecological examination. All participants in the study completed a specially designed anonymous
questionnaire. For the detection of HPV DNA, two commercial kits – High Risk HPV Real-TM and
Low Risk HPV 6/11 Real-TM (Sacace Biotechnologies, Como, Italy) were used. Thirty positive samples were
retested by GenoFlow HPV Array Test (DiagCor Bioscience Incorporation Limited, Hong Kong, China).
The overall prevalence rate of HPV was 61.6%. The most common HPV types in the present
study were as follows: HPV 16, 31, 51, 52, and 18. Female students with only one sexual partner had
significantly lower chance of having HPV infection. Other variables describing lifestyle did not show
statistical significance.
The present paper provides data on the prevalence of high- and low-risk HPV genotypes
among university students in Novi Sad. Obtained results indicate the need for educational activities on
sexually transmitted infections, including HPV, together with promotion of healthy lifestyles. According
to our results, bivalent and quadrivalent prophylactic vaccines have the potential to prevent over 50% of
infections. Percentage of protection with a second-generation prophylactic nonavalent vaccine would
be more than 80%. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 0370-8179 2406-0895 |
| DOI: | 10.2298/SARH1606300K |