Search Results - "Vinal, David"
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Cardiac monitoring during trastuzumab therapy in metastatic breast cancer: early incidence of cardiac dysfunction
Published in Monaldi archives for chest disease (17-02-2022)“…Trastuzumab therapy has dramatically changed breast cancer prognosis. Consensus documents recommend a close monitoring during therapy, not always feasible,…”
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Gp-100 as a Novel Therapeutic Target in Uveal Melanoma
Published in Cancers (27-11-2021)“…Uveal melanoma is a rare neoplasm with poor prognosis in the metastatic setting. Unlike cutaneous melanoma, treatment with kinase inhibitors or immune…”
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3
Total neoadjuvant therapy with or without aflibercept in rectal cancer: 3-year results of GEMCAD-1402
Published in JNCI : Journal of the National Cancer Institute (06-12-2023)“…The results of the Grupo Español Multidisciplinar en Cáncer Digestivo (GEMCAD)-1402 phase II randomized trial suggested that adding aflibercept to modified…”
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4
Functional proteomics of colon cancer Consensus Molecular Subtypes
Published in British journal of cancer (01-06-2024)“…Background The Colorectal Cancer Subtyping Consortium established four Consensus Molecular Subtypes (CMS) in colorectal cancer: CMS1…”
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5
ddPCR Overcomes the CRISPR-Cas13a-Based Technique for the Detection of the BRAF p.V600E Mutation in Liquid Biopsies
Published in International journal of molecular sciences (10-10-2024)“…The isolation of circulating tumoral DNA (ctDNA) present in the bloodstream brings about the opportunity to detect genomic aberrations from the tumor of…”
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Efficacy of second and third lines of treatment in advanced soft tissue sarcomas: a real-world study
Published in Clinical & translational oncology (01-12-2023)“…Background Soft tissue sarcomas (STSs) are an uncommon and heterogeneous group of tumours. Several drugs and combinations have been used in clinical practice…”
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The Relationship between the Expression of GATA4 and GATA6 with the Clinical Characteristics and Prognosis of Resectable Pancreatic Adenocarcinoma
Published in Biomedicines (18-01-2023)“…GATA4 and GATA6 are transcription factors involved in the differentiation and development of PDAC. GATA6 expression is related to the classic molecular…”
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Understanding the immune response and the current landscape of immunotherapy in pancreatic cancer
Published in World journal of gastroenterology : WJG (28-10-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor with high lethality. Even with surgery, radiotherapy, chemotherapy, and other locoregional or…”
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Clinical Score to Predict Recurrence in Patients with Stage II and Stage III Colon Cancer
Published in Cancers (29-11-2022)“…Background: The prognosis of patients with stage II and stage III colon cancer is heterogeneous. Clinical and pathological characteristics, such as tumor…”
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Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries
Published in Journal for immunotherapy of cancer (01-11-2022)“…BackgroundAs management and prevention strategies against COVID-19 evolve, it is still uncertain whether prior exposure to immune checkpoint inhibitors (ICIs)…”
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Tailored chemotherapy for colorectal cancer peritoneal metastases based on a drug-screening platform in patient-derived organoids: a case report
Published in Journal of gastrointestinal oncology (28-02-2023)“…Peritoneal metastasis from colorectal cancer (CRC) has limited therapeutic options and poor prognosis. Systemic chemotherapy combined with cytoreductive…”
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In‐depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer
Published in Molecular oncology (01-07-2022)“…Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the…”
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Impact of epidermal growth factor receptor (EGFR) activating mutations and their targeted treatment in the prognosis of stage IV non-small cell lung cancer (NSCLC) patients harboring liver metastasis
Published in Journal of translational medicine (07-08-2015)“…Liver metastases appear in 20-30% of patients diagnosed with non-small cell lung cancer (NSCLC) and represent a poor prognosis feature of NSCLC and a possibly…”
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Clinico-Pathological Features, Outcomes and Impacts of COVID-19 Pandemic on Patients with Early-Onset Colorectal Cancer: A Single-Institution Experience
Published in Cancers (24-08-2023)“…Background: The rising incidence of colorectal cancer (CRC) among young patients is alarming. We aim to characterize the clinico-pathological features and…”
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ΔNp73, TAp73 and Δ133p53 Extracellular Vesicle Cargo as Early Diagnosis Markers in Colorectal Cancer
Published in Cancers (07-05-2021)“…The early diagnosis of colorectal cancer is a key factor in the overall survival of the patients. The actual screening programs include different approaches…”
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Outcomes of CD19-Directed Chimeric Antigen Receptor T Cell Therapy for Transformed Nonfollicular Lymphoma
Published in Transplantation and cellular therapy (01-06-2023)“…•Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) showed efficacy in relapsed/refractory transformed nonfollicular lymphomas (tNFLs),…”
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An International Comparison of Presentation, Outcomes and CORONET Predictive Score Performance in Patients with Cancer Presenting with COVID-19 across Different Pandemic Waves
Published in Cancers (16-08-2022)“…Patients with cancer have been shown to have increased risk of COVID-19 severity. We previously built and validated the COVID-19 Risk in Oncology Evaluation…”
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Establishment of CORONET, COVID-19 Risk in Oncology Evaluation Tool, to Identify Patients With Cancer at Low Versus High Risk of Severe Complications of COVID-19 Disease On Presentation to Hospital
Published in JCO clinical cancer informatics (01-05-2022)“…Patients with cancer are at increased risk of severe COVID-19 disease, but have heterogeneous presentations and outcomes. Decision-making tools for hospital…”
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482 COVID-19 in patients with lung cancer receiving immunotherapy. A report from an spanish academic center
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundCOVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared pandemic in March 2020. We know that patients with…”
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Application of GPT-4 foundation model for risk prediction and stratification in colorectal cancer
Published in Journal of clinical oncology (20-01-2024)“…219 Background: Deep Learning Language Models (LLMs) show significant potential in analyzing complex data, particularly in oncology, where they can predict and…”
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