Search Results - "Vin, Chintan D."

Design of a titering assay for lentiviral vectors utilizing direct extraction of DNA from transduced cells in microtiter plates by Murphy, Michele E, Vin, Chintan D, Slough, Megan M, Gombotz, Wayne R, Kelley-Clarke, Brenna

“…Using lentiviral vector products in clinical applications requires an accurate method for measuring transduction titer. For vectors lacking a marker gene,…”
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Design of a Novel Integration-deficient Lentivector Technology That Incorporates Genetic and Posttranslational Elements to Target Human Dendritic Cells by Tareen, Semih U, Kelley-Clarke, Brenna, Nicolai, Christopher J, Cassiano, Linda A, Nelson, Lisa T, Slough, Megan M, Vin, Chintan D, Odegard, Jared M, Sloan, Derek D, Van Hoeven, Neal, Allen, James M, Dubensky, Thomas W, Robbins, Scott H

“…As sentinels of the immune system, dendritic cells (DCs) play an essential role in regulating cellular immune responses. One of the main challenges of…”
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Virological and preclinical characterization of a dendritic cell targeting, integration-deficient lentiviral vector for cancer immunotherapy by Odegard, Jared M, Kelley-Clarke, Brenna, Tareen, Semih U, Campbell, David J, Flynn, Patrick A, Nicolai, Christopher J, Slough, Megan M, Vin, Chintan D, McGowan, Patrick J, Nelson, Lisa T, Ter Meulen, Jan, Dubensky, Jr, Thomas W, Robbins, Scott H

“…Dendritic cells (DCs) are essential antigen-presenting cells for the initiation of cytotoxic T-cell responses and therefore attractive targets for cancer…”
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A Rev-Independent gag/pol Eliminates Detectable psi-gag Recombination in Lentiviral Vectors by Tareen, Semih U, Nicolai, Christopher J, Campbell, David J, Flynn, Patrick A, Slough, Megan M, Vin, Chintan D, Kelley-Clarke, Brenna, Odegard, Jared M, Robbins, Scott H

“…Lentiviral vectors (LVs) are being developed for clinical use in humans for applications including gene therapy and immunotherapy. A safety concern for use of…”
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Abstract 702: DCVex(TM): A novel integration-deficient lentivector technology that incorporates genetic and post-translational elements to target dendritic cells by Tareen, Semih U., Kelley-Clarke, Brenna, Nicolai, Christopher J., Slough, Megan M., Vin, Chintan D., Hoeven, Neal Van, Robbins, Scott H., Meulen, Jan H. ter, Berglund, Peter

“…With the goal of creating antigen-directed immunotherapeutics that can be safely administered directly to patients, Immune Design has developed a platform of…”
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