Search Results - "Villaronga, MÁ"
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PO-477 A novel role for nanog as an early cancer risk marker in patients with laryngeal precancerous lesions
Published in ESMO open (01-07-2018)“…IntroductionNANOG is a transcription factor involved in embryonic pluripotency maintenance. It has also been shown that it has a mitogenic function in adult…”
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HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions
Published in Oncogene (21-01-2010)“…The hairy/enhancer-of-split related with YRPW motif 1 (HEY1) is a member of the basic-helix-loop-helix-Orange (bHLH-O) family of transcriptional repressors…”
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PO-143 Frequent loss of annexin a1 expression in head and neck squamous cell carcinomas by transcriptional regulatory mechanisms
Published in ESMO open (01-07-2018)“…IntroductionAnnexins are frequently deregulated in many cancers (‘annexinopathies’). Annexin A1 (ANXA1) overexpression has been reported in gastric, pancreatic…”
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PO-490 Expression of cortactin and focal adhesion kinase in early stages of laryngeal tumorigenesis and clinical application for cancer risk-stratification
Published in ESMO open (01-07-2018)“…IntroductionCortactin (CTTN) and the Focal Adhesion Kinase (FAK) are two major candidate genes to respectively drive 11q13- and 8q24-associated aggressive…”
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PO-491 Frequent mTORC1 activation in head and neck squamous cell carcinomas correlates with favourable clinical outcome
Published in ESMO open (01-07-2018)“…IntroductionThe PI3K/AKT/mTOR signalling pathway has emerged as one of the most frequently deregulated in head and neck squamous cell carcinomas (HNSCC),…”
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PO-478 Prognostic significance of E-cadherin and beta-catenin expression in HPV-negative oropharyngeal squamous cell carcinomas
Published in ESMO open (01-07-2018)“…IntroductionMounting evidence show an increasing prevalence of human papillomavirus (HPV) in head and neck squamous cell carcinomas (HNSCC), particularly in…”
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