Search Results - "Villar, José Daniel Figueroa"

Review about Structure and Evaluation of Reactivators of Acetylcholinesterase Inhibited with Neurotoxic Organophosphorus Compounds by Figueroa-Villar, José Daniel, Petronilho, Elaine C, Kuca, Kamil, Franca, Tanos C C

“…Neurotoxic chemical warfare agents can be classified as some of the most dangerous chemicals for humanity. The most effective of those agents are the…”
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Searching for drug leads targeted to the hydrophobic cleft of dengue virus capsid protein by Ortlieb, Liliane O., Caruso, Ícaro P., Mebus-Antunes, Nathane C., Da Poian, Andrea T., Petronilho, Elaine da C., Figueroa-Villar, José Daniel, Nascimento, Claudia J., Almeida, Fabio C. L.

“…We synthesised and screened 18 aromatic derivatives of guanylhydrazones and oximes aromatic for their capacity to bind to dengue virus capsid protein (DENVC)…”
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A new guanylhydrazone derivative as a potential acetylcholinesterase inhibitor for Alzheimer's disease: synthesis, molecular docking, biological evaluation and kinetic studies by nuclear magnetic resonance by Ferreira Neto, Denise Cristian, de Souza Ferreira, Marcelle, da Conceição Petronilho, Elaine, Alencar Lima, Josélia, Oliveira Francisco de Azeredo, Sirlene, de Oliveira Carneiro Brum, Juliana, Jorge do Nascimento, Claudia, Figueroa Villar, José Daniel

“…The development of pharmacological agents for the treatment of Alzheimer's Disease (AD) is very relevant since this is the most common type of dementia. The…”
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Design, synthesis, structure, toxicology and in vitro testing of three novel agents for Alzheimer’s disease by Figueroa-Villar, Jose Daniel

“…This article describes the synthesis of three novel compounds for the treatment of Alzheimer’s disease (AD). The compounds were formed by the reaction of…”
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Complete chemical shift assignment and molecular modeling studies of two chromene derivatives as potential leads for new anticancer drugs by Rubim de Santana, Priscila Ivo, Ferreira Neto, Denise Cristian, Goncalves, Arlan da Silva, Almeida, Joyce Sobreiro Francisco Diz de, França, Tanos Celmar Costa, Figueroa-Villar, José Daniel

“…The compounds 7-chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one (5) and 5-[-7-chloro-2,4-dioxo-1H,…”
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Synthesis and docking studies of three new diaminochromenes as potential leads for anticancer drugs by Tonelli Nogueira, Mariana de Oliveira, Almeida, Joyce Sobreiro Francisco Diz de, Franca, Tanos Celmar Costa, Figueroa-Villar, José Daniel

“…In this work, the new diaminochromenes: 2,5-dimono-8-methoxychromeno[4,3,2-de][1,6]naphthyridine-4-carbonitrile (4),…”
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Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase by Petronilho, Elaine da Conceição, Rennó, Magdalena do Nascimento, Castro, Newton Gonçalves, da Silva, Fernanda Motta R, Pinto, Angelo da Cunha, Figueroa-Villar, José Daniel

“…Analogs of pralidoxime, which is a commercial antidote for intoxication from neurotoxic organophosphorus compounds, were designed, synthesized, characterized,…”
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NMR determination of Electrophorus electricus acetylcholinesterase inhibition and reactivation by neutral oximes by da Cunha Xavier Soares, Sibelle Feitosa, Vieira, Andréia Aguiar, Delfino, Reinaldo Teixeira, Figueroa-Villar, José Daniel

“…Neurotoxic organophosphorus compounds (OPs), which are used as pesticides and chemical warfare agents lead to more than 700,000 intoxications worldwide every…”
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Computational NMR Spectroscopy of Transition-Metal/Nitroimidazole Complexes: Theoretical Investigation of Potential Radiosensitizers by Ramalho, Teodorico C., Bühl, Michael, Figueroa-Villar, José Daniel, de Alencastro, Ricardo Bicca

“…The computed chemical shifts of transition‐metal complexes with dimetridazole (= 1,2‐dimethyl‐5‐nitro‐1H‐imidazole; 1), a prototypical nitro‐imidazole‐based…”
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The use of long range C-H coupling in the structure determination and 13C assignment of pyrones by Villar, José Daniel Figueroa, De Oliveira, Alda Maria

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Nuclear Magnetic Resonance (NMR), Infrared (IR) and Mass Spectrometry (MS) study of keto-enol tautomerism of isobenzofuran-1(3H)-one derivatives by Pires, Diego Arantes Teixeira, Pereira, Wagner Luiz, Teixeira, Róbson Ricardo, Figueroa-Villar, José Daniel, Nascimento, Claudia Jorge do

“…The keto-enol tautomerism of 3-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohexen-1-yl)isobenzofuran-1(3H-one (1),…”
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Kinetics and docking studies of two potential new inhibitors of the nucleoside hydrolase from Leishmania donovani by Rennó, Magdalena Nascimento, França, Tanos Celmar Costa, Nico, Dirlei, Palatnik-de-Sousa, Clarisa B., Tinoco, Luzineide Wanderley, Figueroa-Villar, José Daniel

“…In this study the recombinant enzyme nucleoside hydrolase of Leishmania donovani (rLdNH) was expressed in Escherichia coli in connection with maltose binding…”
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Certified Reference Material for Traceability in Environmental Analysis: PAHs in Toluene by Guimarães, Evelyn de F., Rego, Eliane C. P. do, Cunha, Helen C. M., Rodrigues, Janaína M., Figueroa-Villar, José Daniel

“…Certified reference material (CRM) plays a vital role for quality control assurance in environmental analysis, because the quality of data arising from…”
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Spin-lattice relaxation time in drug discovery and design by Figueroa-Villar, José Daniel, Tinoco, Luzineide Wanderley

“…NMR is one of the most powerful techniques for ligand-biomolecule interaction studies and drug screening and design. There are several methods that are…”
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Identification of citrinin as the defence metabolite of Penicillium corylophilum stressed with the antagonist fungus Beauveria bassiana by dos Santos, Claudia Maria Campinha, Costa, Gisela Lara da, Figueroa-Villar, José Daniel

“…Penicillium corylophilum isolated from mosquitoes was cultivated in liquid media leading to the first reported identification of citrinin (1a) as one metabolic…”
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NMR interaction studies of aromatic guanyl hydrazones with micelles: Model for mechanism of action of cationic antibiotics by Borges, Márcia Narcizo, Figueroa-Villar, José Daniel

“…Interaction studies using hydrogen NMR spin–lattice relaxation time measurements of a series of five antiparasitic guanyl hydrazones with SDS and cetyl…”
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Defesa química: histórico, classificação dos agentes de guerra e ação dos neurotóxicos by Silva, Gustavo Rocha, Borges Jr, Itamar, Figueroa-Villar, José Daniel, Castro, Alexandre Taschetto de

“…Chemical agents are substances used for their toxic effects on humans, animals and plants. The main objective of chemical defense is to develop systems that…”
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Design, docking studies and molecular dynamics of new potential selective inhibitors of Plasmodium falciparum serine hydroxymethyltransferase by da Silva, Manuela Leal, da Silva Gonçalves, Arlan, Ricardo Batista, Paulo, Figueroa-Villar, José Daniel, Pascutti, Pedro Geraldo, França, Tanos Celmar Costa

“…In this paper, former studies on the interactions of the natural substrate and potential inhibitors of Plasmodium falciparum serine hydroxymethyltransferase…”
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SHESSLOC: A selective variation of the FUCOUP sequence by do Nascimento, Claudia Jorge, Figueroa-Villar, José Daniel

“…In this paper we carried out a comparison between all the possible selective versions of the basic heteronuclear correlation experiment, the FUCOUP sequence…”
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New semicarbazones as gorge-spanning ligands of acetylcholinesterase and potential new drugs against Alzheimer's disease: Synthesis, molecular modeling, NMR, and biological evaluation by Ferreira Neto, Denise Cristian, Alencar Lima, Josélia, Sobreiro Francisco Diz de Almeida, Joyce, Costa França, Tanos Celmar, Jorge do Nascimento, Claudia, Figueroa Villar, José Daniel

“…Two new compounds (E)-2-(5,7-dibromo-3,3-dimethyl-3,4-dihydroacridin-1(2H)-ylidene)hydrazinecarbothiomide (3) and…”
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