Search Results - "Villano, Daisy"
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A fast multislice sequence for 3D MRI‐CEST pH imaging
Published in Magnetic resonance in medicine (01-03-2021)“…Purpose Chemical exchange saturation transfer MRI can provide accurate pH images, but the slow scan time (due to long saturation periods and multiple offsets…”
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Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential
Published in British journal of cancer (05-01-2021)“…Background Tumour acidosis is considered to play a central role in promoting cancer invasion and migration, but few studies have investigated in vivo how…”
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GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[18F]F-FDG-PET
Published in Molecular imaging and biology (01-02-2022)“…Purpose Triple-negative breast cancer (TNBC) patients have usually poor outcome after chemotherapy and early prediction of therapeutic response would be…”
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Development and Validation of Four Different Methods to Improve MRI-CEST Tumor pH Mapping in Presence of Fat
Published in Journal of imaging (12-07-2024)“…CEST-MRI is an emerging imaging technique suitable for various in vivo applications, including the quantification of tumor acidosis. Traditionally, CEST…”
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Effect of Esomeprazole Treatment on Extracellular Tumor pH in a Preclinical Model of Prostate Cancer by MRI-CEST Tumor pH Imaging
Published in Metabolites (28-12-2022)“…Novel anticancer treatments target the pH regulating system that plays a major role in tumor progression by creating an acidic microenvironment, although few…”
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Assessing the Therapeutic Efficacy of Proton Transport Inhibitors in a Triple-Negative Breast Cancer Murine Model with Magnetic Resonance Imaging—Chemical Exchange Saturation Transfer Tumor pH Imaging
Published in Metabolites (01-11-2023)“…Proton transporters play a key role in maintaining the acidic tumor microenvironment; hence, their inhibition has been proposed as a new therapeutic treatment,…”
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Evaluation of a similarity anisotropic diffusion denoising approach for improving in vivo CEST‐MRI tumor pH imaging
Published in Magnetic resonance in medicine (01-06-2021)“…Purpose Chemical exchange saturation transfer MRI provides new approaches for investigating tumor microenvironment, including tumor acidosis that plays a key…”
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Enabling Characterisation of the NAD+ Biosynthesis Pathway via in vitro CEST MRI
Published in Alzheimer's & dementia (01-12-2022)“…Background The Chemical Exchange Saturation Transfer (CEST) MRI properties of six metabolites required for synthesis of coenzyme nicotinamide adenine…”
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Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…The kidney plays a major role in maintaining body pH homeostasis. Renal pH, in particular, changes immediately following injuries such as intoxication and…”
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In Vivo MRI-CEST Tumor pH Imaging Detects Resistance to Proton Pump Inhibitors in Human Prostate Cancer Murine Models
Published in Cancers (01-10-2022)“…The tumor microenvironment acidification confers treatment resistance; therefore, the interference with pH regulating systems is considered a new therapeutic…”
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