Search Results - "Villamarín, Xando Diaz"
-
1
The study protocol for a non-randomized controlled clinical trial using a genotype-guided strategy in a dataset of patients who undergone percutaneous coronary intervention with stent
Published in Data in brief (01-02-2017)“…This article contains data related to the research article entitled “Results of genotype–guided antiplatelet therapy in patients undergone percutaneous…”
Get full text
Journal Article -
2
Pharmacogenetics of siponimod: A systematic review
Published in Biomedicine & pharmacotherapy (01-09-2022)“…Multiple sclerosis is a chronic inflammatory neurological disease, and siponimod (Mayzent) is the first oral treatment option for adult patients with secondary…”
Get full text
Journal Article -
3
Azathioprine dose tailoring based on pharmacogenetic information: Insights of clinical implementation
Published in Biomedicine & pharmacotherapy (01-12-2023)“…Azathioprine is commonly used as an immunosuppressive antimetabolite in the treatment of acute lymphoblastic leukemia, autoimmune disorders (such as Crohn's…”
Get full text
Journal Article -
4
Economic evaluation of pharmacogenomic-guided antiplatelet treatment in Spanish patients suffering from acute coronary syndrome participating in the U-PGx PREPARE study
Published in Human genomics (07-06-2023)“…Cardiovascular diseases and especially Acute Coronary Syndrome (ACS) constitute a major health issue impacting millions of patients worldwide. Being a leading…”
Get full text
Journal Article -
5
Pharmacogenetic polymorphisms affecting bisoprolol response
Published in Biomedicine & pharmacotherapy (01-10-2021)“…β-blockers are commonly prescribed to treat multiple cardiovascular (CV) diseases, but, frequently, adverse drug reactions and intolerance limit their use in…”
Get full text
Journal Article -
6
Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention
Published in The pharmacogenomics journal (01-10-2019)“…Clopidogrel is an antiplatelet drug given to patients before and after having a percutaneous coronary intervention (PCI). Genomic variants in the CYP2C19 gene…”
Get full text
Journal Article -
7
Novel Genetic Variants Explaining Severe Adverse Drug Events after Clinical Implementation of DPYD Genotype-Guided Therapy with Fluoropyrimidines: An Observational Study
Published in Pharmaceutics (19-07-2024)“…Fluoropyrimidines (FPs) are commonly prescribed in many cancer streams. The EMA and FDA-approved drug labels for FPs recommend genotyping the *2A (rs3918290),…”
Get full text
Journal Article -
8
Genetic Polymorphisms in VEGFR Coding Genes ( FLT1 / KDR ) on Ranibizumab Response in High Myopia and Choroidal Neovascularization Patients
Published in Pharmaceutics (26-07-2022)“…A severe form of myopia defined as pathologic/high myopia is the main cause of visual impairment and one of the most frequent causes of blindness worldwide. It…”
Get full text
Journal Article -
9
A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population
Published in PloS one (15-03-2016)“…There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the…”
Get full text
Journal Article -
10
Genetic Polymorphisms Affecting Ranibizumab Response in High Myopia Patients
Published in Pharmaceutics (20-11-2021)“…High myopia is an ophthalmic pathology that affects half of the young adults in the United States and Europe and it is predicted that a third of the world’s…”
Get full text
Journal Article -
11
Results of genotype-guided antiplatelet therapy in patients who undergone percutaneous coronary intervention with stent
Published in International journal of cardiology (15-12-2016)“…Clopidogrel has provided beneficial effects in acute coronary syndrome and percutaneous coronary intervention. Different polymorphisms have been associated…”
Get full text
Journal Article -
12
Genetic Variants Affecting Anti-VEGF Drug Response in Polypoidal Choroidal Vasculopathy Patients: A Systematic Review and Meta-Analysis
Published in Genes (12-11-2020)“…Polypoidal choroidal vasculopathy (PCV) is usually regarded as a subtype of choroidal neovascularization (CNV) that is secondary to age-related macular…”
Get full text
Journal Article -
13
Pharmacogenetics in the Treatment of Cardiovascular Diseases and Its Current Progress Regarding Implementation in the Clinical Routine
Published in Genes (01-04-2019)“…There is a special interest in the implementation of pharmacogenetics in clinical practice, although there are some barriers that are preventing this…”
Get full text
Journal Article -
14
Genetic polymorphisms influence on the response to clopidogrel in peripheral artery disease patients following percutaneous transluminal angioplasty
Published in Pharmacogenomics (01-08-2016)“…To study the association of and polymorphisms and the clopidogrel response in Spanish peripheral artery disease patients following percutaneous transluminal…”
Get full text
Journal Article -
15
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
Published in The Lancet (British edition) (04-02-2023)“…The benefit of pharmacogenetic testing before starting drug therapy has been well documented for several single gene–drug combinations. However, the clinical…”
Get full text
Journal Article -
16
Pharmacogenomics decision support in the U-PGx project: Results and advice from clinical implementation across seven European countries
Published in PloS one (08-06-2022)“…The clinical implementation of pharmacogenomics (PGx) could be one of the first milestones towards realizing personalized medicine in routine care. However,…”
Get full text
Journal Article -
17
Selective Digestive Decontamination: A Comprehensive Approach to Reducing Nosocomial Infections and Antimicrobial Resistance in the ICU
Published in Journal of clinical medicine (29-10-2024)“…Background/Objective: Multidrug-resistant (MDR) bacteria pose a significant threat to global health, especially in intensive care units (ICUs), where high…”
Get full text
Journal Article -
18
Results of genotype–guided antiplatelet therapy in patients undergone percutaneous coronary intervention with stent
Published in International journal of cardiology (2016)“…Abstract Background Clopidogrel has provided beneficial effects in acute coronary syndrome and percutaneous coronary intervention. Different polymorphisms have…”
Get full text
Journal Article -
19
A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population: e0150456
Published in PloS one (01-03-2016)“…There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the…”
Get full text
Journal Article