Search Results - "Villalobos, Victor M."

Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis by Willis, Scooter, Villalobos, Victor M, Gevaert, Olivier, Abramovitz, Mark, Williams, Casey, Sikic, Branimir I, Leyland-Jones, Brian

“…To discover novel prognostic biomarkers in ovarian serous carcinomas. A meta-analysis of all single genes probes in the TCGA and HAS ovarian cohorts was…”
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Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC‐3G3) to patients with advanced soft tissue sarcoma by Villalobos, Victor M., Mo, Gary, Agulnik, Mark, Pollack, Seth M., Rushing, Daniel A., Singh, Arun, Van Tine, Brian A., McNaughton, Rhian, Decker, Rodney L., Zhang, Wei, Shahir, Ashwin, Cronier, Damien M.

“…Background Olaratumab, a fully human monoclonal antibody, selectively binds to human platelet‐derived growth factor receptor alpha and blocks ligand binding…”
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Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial by Trigo, José, Subbiah, Vivek, Besse, Benjamin, Moreno, Victor, López, Rafael, Sala, María Angeles, Peters, Solange, Ponce, Santiago, Fernández, Cristian, Alfaro, Vicente, Gómez, Javier, Kahatt, Carmen, Zeaiter, Ali, Zaman, Khalil, Boni, Valentina, Arrondeau, Jennifer, Martínez, Maite, Delord, Jean-Pierre, Awada, Ahmad, Kristeleit, Rebecca, Olmedo, Maria Eugenia, Wannesson, Luciano, Valdivia, Javier, Rubio, María Jesús, Anton, Antonio, Sarantopoulos, John, Chawla, Sant P, Mosquera-Martinez, Joaquín, D'Arcangelo, Manolo, Santoro, Armando, Villalobos, Victor M, Sands, Jacob, Paz-Ares, Luis

“…Few options exist for treatment of patients with small-cell lung cancer (SCLC) after failure of first-line therapy. Lurbinectedin is a selective inhibitor of…”
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Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study by Gounder, Mrinal, Schöffski, Patrick, Jones, Robin L, Agulnik, Mark, Cote, Gregory M, Villalobos, Victor M, Attia, Steven, Chugh, Rashmi, Chen, Tom Wei-Wu, Jahan, Thierry, Loggers, Elizabeth T, Gupta, Abha, Italiano, Antoine, Demetri, George D, Ratan, Ravin, Davis, Lara E, Mir, Olivier, Dileo, Palma, Van Tine, Brian A, Pressey, Joseph G, Lingaraj, Trupti, Rajarethinam, Anand, Sierra, Laura, Agarwal, Shefali, Stacchiotti, Silvia

“…Epithelioid sarcoma is a rare and aggressive soft-tissue sarcoma subtype. Over 90% of tumours have lost INI1 expression, leading to oncogenic dependence on the…”
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Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma by Tap, William D, Villalobos, Victor M, Cote, Gregory M, Burris, Howard, Janku, Filip, Mir, Olivier, Beeram, Murali, Wagner, Andrew J, Jiang, Liewen, Wu, Bin, Choe, Sung, Yen, Katharine, Gliser, Camelia, Fan, Bin, Agresta, Sam, Pandya, Shuchi S, Trent, Jonathan C

“…Surgery is the primary therapy for localized chondrosarcoma; for locally advanced and/or metastatic disease, no known effective systemic therapy exists…”
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Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors by Gammon, Seth T., Villalobos, Victor M., Roshal, Mikhail, Samrakandi, Mustapha, Piwnica-Worms, David

“…Bioluminescence resonance energy transfer (BRET) systems to date have been dominated by use of blue‐green Renilla luciferase (Rluc) as the energy donor…”
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Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors by Burris, Howard A, Infante, Jeffrey R, Ansell, Stephen M, Nemunaitis, John J, Weiss, Geoffrey R, Villalobos, Victor M, Sikic, Branimir I, Taylor, Matthew H, Northfelt, Donald W, Carson, 3rd, William E, Hawthorne, Thomas R, Davis, Thomas A, Yellin, Michael J, Keler, Tibor, Bullock, Timothy

“…Purpose CD27, a costimulatory molecule on T cells, induces intracellular signals that mediate cellular activation, proliferation, effector function, and cell…”
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First-in-Human Phase I Study of ABBV-085, an Antibody-Drug Conjugate Targeting LRRC15, in Sarcomas and Other Advanced Solid Tumors by Demetri, George D, Luke, Jason J, Hollebecque, Antoine, Powderly, 2nd, John D, Spira, Alexander I, Subbiah, Vivek, Naumovski, Louie, Chen, Chris, Fang, Hua, Lai, Dominic W, Yue, Huibin, Polepally, Akshanth R, Purcell, James W, Robinson, Randy, Sharma, Padmanee, Allison, James P, Tolcher, Anthony, Villalobos, Victor M

“…Leucine-rich repeat containing 15 (LRRC15) is expressed on stromal fibroblasts in the tumor microenvironment of multiple solid tumor types and may represent an…”
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We can study ultrarare tumors effectively in this day and age, it just takes a cooperative approach: The role of dasatinib in assorted indolent sarcomas by Villalobos, Victor M., Hoffner, Brianna, Elias, Anthony D.

“…Dasatinib may be an active agent in assorted indolent sarcomas. The impact of endpoint selection, well‐defined cohorts, and responses (Choi criteria vs…”
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Ready or Not, Here I Come: Inflammatory Myofibroblastic Tumors With Kinase Alterations Revealed Through Molecular Hide and Seek by Davies, Kurtis D, Villalobos, Victor M, Aisner, Dara L

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Real‐world outcomes of patients with locally advanced or metastatic epithelioid sarcoma by Gounder, Mrinal M., Merriam, Priscilla, Ratan, Ravin, Patel, Shreyaskumar R., Chugh, Rashmi, Villalobos, Victor M., Thornton, Mark, Van Tine, Brian A., Abdelhamid, Amr H., Whalen, Jennifer, Yang, Jay, Rajarethinam, Anand, Duh, Mei Sheng, Bobbili, Priyanka J., Huynh, Lynn, Totev, Todor I., Lax, Angela K., Agarwal, Shefali, Demetri, George D.

“…Background Limited data are available on the real‐world effectiveness and safety of systemic therapies for advanced (surgically unresectable and/or metastatic)…”
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Targeting ALK in inflammatory myofibroblastic tumours by Villalobos, Victor M, Camidge, D Ross

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Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment by Subbiah, Vivek, Paz-Ares, Luis, Besse, Benjamin, Moreno, Victor, Peters, Solange, Sala, María Angeles, López-Vilariño, José Antonio, Fernández, Cristian, Kahatt, Carmen, Alfaro, Vicente, Siguero, Mariano, Zeaiter, Ali, Zaman, Khalil, López, Rafael, Ponce, Santiago, Boni, Valentina, Arrondeau, Jennifer, Delord, Jean-Pierre, Martínez, Maite, Wannesson, Luciano, Antón, Antonio, Valdivia, Javier, Awada, Ahmad, Kristeleit, Rebecca, Olmedo, Maria Eugenia, Rubio, María Jesús, Sarantopoulos, John, Chawla, Sant P., Mosquera-Martinez, Joaquín, D’ Arcangelo, Manolo, Santoro, Armando, Villalobos, Victor M., Sands, Jacob, Trigo, José

“…•The NCCN recommends first-line re-challenge for relapsed SCLC with CTFI ≥ 180 days.•This recommendation is based on data from small trials from the…”
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Permeation Peptide Conjugates for In Vivo Molecular Imaging Applications by Bullok, Kristin E., Gammon, Seth T., Violini, Stefania, Prantner, Andrew M., Villalobos, Victor M., Sharma, Vijay, Piwnica-Worms, David

“…Rapid and efficient delivery of imaging probes to the cell interior using permeation peptides has enabled novel applications in molecular imaging. Membrane…”
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Targeted Therapies in the Treatment of Sarcomas by Hoffner, Brianna, Elias, Anthony D., Villalobos, Victor M.

“…About 50% of sarcomas have specific pathology-defining molecular alterations including mutations, fusion genes, and gene amplifications. Some of these…”
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National Soil Strategy for Sustainable Agriculture ( ENASAS ): A new systemic approach in Mexico by Ortiz‐García, Sol, Torres‐Gómez, Mariano, Benavides, Adalberto, Anaya, Manuel, Anglés‐Hernández, Marisol, Cerón, Areli, Cotler, Helena, Cueto‐Wong, José A., Etchevers, Jorge D., Fernández‐Luqueño, Fabián, Gonzalez‐Meraz, Jorge, Guerrero‐Peña, Armando, Meneses, Marco, Miranda, María, Pérez, Mario, Pulido, Leonardo, Reyes‐Sánchez, Laura Bertha, Reynoso, Verónica, Saynes, Vinisa, Villalobos‐Arámbula, Víctor M., Prado, Blanca, Guevara, Mario

“…The National Soil Strategy for Sustainable Agriculture (ENASAS) arises in response to the increasing need to organize, coordinate and strengthen the…”
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A retrospective cohort study of treatment patterns among patients with metastatic soft tissue sarcoma in the US by Villalobos, Victor M, Byfield, Stacey DaCosta, Ghate, Sameer R, Adejoro, Oluwakayode

“…Since treatment patterns in metastatic soft tissue sarcoma (mSTS) have not been studied subsequent to US approval of pazopanib in 2012, this study sought to…”
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Quantitative Analysis of Permeation Peptide Complexes Labeled with Technetium-99m:  Chiral and Sequence-Specific Effects on Net Cell Uptake by Gammon, Seth T, Villalobos, Victor M, Prior, Julie L, Sharma, Vijay, Piwnica-Worms, David

“…This study investigated sequence-specific cell uptake characteristics of Tat basic domain and related permeation peptides with an emphasis on residue…”
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Synthesis and biological evaluation of aryl azide derivatives of combretastatin a-4 as molecular probes for tubulin by Pinney, Kevin G, Mejia, Maria P, Villalobos, Victor M, Rosenquist, Brent E, Pettit, George R, Verdier-Pinard, Pascal, Hamel, Ernest

“…Two new aryl azides, ( Z)-1-(3′-azido-4′-methoxyphenyl)-2-(3″,4″,5″-trimethoxyphenyl)ethene 9 and (…”
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Efficient Plant Regeneration of Garlic (Allium sativum L.) by Root-Tip Culture by Alejandrina Robledo-Paz, Víctor M. Villalobos-Arámbula, Alba E. Jofre-Garfias

“…Root apices from in vitro cultured garlic (Allium sativum) cloves of cvs. ABEN and GT96-1 were used as axenic explants for organogenic callus production and…”
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