Search Results - "Villalobos, Alan"

Gene Designer: a synthetic biology tool for constructing artificial DNA segments by Villalobos, Alan, Ness, Jon E, Gustafsson, Claes, Minshull, Jeremy, Govindarajan, Sridhar

“…Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization,…”
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Design parameters to control synthetic gene expression in Escherichia coli by Welch, Mark, Govindarajan, Sridhar, Ness, Jon E, Villalobos, Alan, Gurney, Austin, Minshull, Jeremy, Gustafsson, Claes

“…Production of proteins as therapeutic agents, research reagents and molecular tools frequently depends on expression in heterologous hosts. Synthetic genes are…”
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The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology by Galdzicki, Michal, Clancy, Kevin P, Oberortner, Ernst, Pocock, Matthew, Quinn, Jacqueline Y, Rodriguez, Cesar A, Roehner, Nicholas, Wilson, Mandy L, Adam, Laura, Anderson, J Christopher, Bartley, Bryan A, Beal, Jacob, Chandran, Deepak, Chen, Joanna, Densmore, Douglas, Endy, Drew, Grünberg, Raik, Hallinan, Jennifer, Hillson, Nathan J, Johnson, Jeffrey D, Kuchinsky, Allan, Lux, Matthew, Misirli, Goksel, Peccoud, Jean, Plahar, Hector A, Sirin, Evren, Stan, Guy-Bart, Villalobos, Alan, Wipat, Anil, Gennari, John H, Myers, Chris J, Sauro, Herbert M

“…The synthetic biology research community describes a standard language for exchanging designs of biological 'parts'. The re-use of previously validated designs…”
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You're one in a googol: optimizing genes for protein expression by Welch, Mark, Villalobos, Alan, Gustafsson, Claes, Minshull, Jeremy

“…A vast number of different nucleic acid sequences can all be translated by the genetic code into the same amino acid sequence. These sequences are not all…”
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family of thermostable fungal cellulases created by structure-guided recombination by Heinzelman, Pete, Snow, Christopher D, Wu, Indira, Nguyen, Catherine, Villalobos, Alan, Govindarajan, Sridhar, Minshull, Jeremy, Arnold, Frances H

“…SCHEMA structure-guided recombination of 3 fungal class II cellobiohydrolases (CBH II cellulases) has yielded a collection of highly thermostable CBH II…”
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SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability by Heinzelman, Pete, Snow, Christopher D., Smith, Matthew A., Yu, Xinlin, Kannan, Arvind, Boulware, Kevin, Villalobos, Alan, Govindarajan, Sridhar, Minshull, Jeremy, Arnold, Frances H.

“…A quantitative linear model accurately (R2 = 0.88) describes the thermostabilities of 54 characterized members of a family of fungal cellobiohydrolase class II…”
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Engineering genes for predictable protein expression by Gustafsson, Claes, Minshull, Jeremy, Govindarajan, Sridhar, Ness, Jon, Villalobos, Alan, Welch, Mark

“…► Traditional bioengineering is limited by the lack of systematic methodology. ► Studies of synthetic gene expression have questioned beliefs about gene…”
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Designing genes for successful protein expression by Welch, Mark, Villalobos, Alan, Gustafsson, Claes, Minshull, Jeremy

“…DNA sequences are now far more readily available in silico than as physical DNA. De novo gene synthesis is an increasingly cost-effective method for building…”
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Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin by Midelfort, Katarina S., Kumar, Rajesh, Han, Seungil, Karmilowicz, Michael J., McConnell, Kevin, Gehlhaar, Daniel K., Mistry, Anil, Chang, Jeanne S., Anderson, Marie, Villalobos, Alan, Minshull, Jeremy, Govindarajan, Sridhar, Wong, John W.

“…Several protein engineering approaches were combined to optimize the selectivity and activity of Vibrio fluvialis aminotransferase (Vfat) for the synthesis of…”
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In silico design of functional DNA constructs by Villalobos, Alan, Welch, Mark, Minshull, Jeremy

“…The promise of synthetic biology lies in the creation of novel function from the proper combination of genetic elements. De novo gene synthesis has become a…”
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Model accounting for the Cr(III) electroprecipitation kinetics in an electrochemical reactor based on CFD and mass transport contributions by Villalobos-Lara, Alan D., Castillo, Benjamín, Rivera, Fernando F., Vazquez-Arenas, Jorge

“…[Display omitted] •Phenomenological theoretical model of Cr electroprecipitation in synthetic solution.•Model accounts for kinetics, momentum and mass…”
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