Search Results - "Villain, Nicolas"

The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson's disease by Biondetti, Emma, Santin, Mathieu D, Valabrègue, Romain, Mangone, Graziella, Gaurav, Rahul, Pyatigorskaya, Nadya, Hutchison, Matthew, Yahia-Cherif, Lydia, Villain, Nicolas, Habert, Marie-Odile, Arnulf, Isabelle, Leu-Semenescu, Smaranda, Dodet, Pauline, Vila, Miquel, Corvol, Jean-Christophe, Vidailhet, Marie, Lehéricy, Stéphane

“…In Parkinson's disease, there is a progressive reduction in striatal dopaminergic function, and loss of neuromelanin-containing dopaminergic neurons and…”
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Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease by Chételat, Gaël, La Joie, Renaud, Villain, Nicolas, Perrotin, Audrey, de La Sayette, Vincent, Eustache, Francis, Vandenberghe, Rik

“…Recent developments of PET amyloid ligands have made it possible to visualize the presence of Aβ deposition in the brain of living participants and to assess…”
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Age effect on the default mode network, inner thoughts, and cognitive abilities by Mevel, Katell, Landeau, Brigitte, Fouquet, Marine, La Joie, Renaud, Villain, Nicolas, Mézenge, Florence, Perrotin, Audrey, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël

“…Abstract Age-related effects on the default mode network (DMN) connectivity as measured at rest using functional magnetic resonance imaging (fMRI) are now well…”
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Jumping Stand Apparatus Reveals Rapidly Specific Age-Related Cognitive Impairments in Mouse Lemur Primates by Picq, Jean-Luc, Villain, Nicolas, Gary, Charlotte, Pifferi, Fabien, Dhenain, Marc

“…The mouse lemur (Microcebus murinus) is a promising primate model for investigating normal and pathological cerebral aging. The locomotor behavior of this…”
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Differential effect of age on hippocampal subfields assessed using a new high-resolution 3T MR sequence by La Joie, Renaud, Fouquet, Marine, Mézenge, Florence, Landeau, Brigitte, Villain, Nicolas, Mevel, Katell, Pélerin, Alice, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël

“…Recent advances in neuroimaging have highlighted the interest to differentiate hippocampal subfields for cognitive neurosciences and more notably in assessing…”
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Mass Spectrometry for Neurobiomarker Discovery: The Relevance of Post-Translational Modifications by Azevedo, Rita, Jacquemin, Chloé, Villain, Nicolas, Fenaille, François, Lamari, Foudil, Becher, François

“…Neurodegenerative diseases are incurable, heterogeneous, and age-dependent disorders that challenge modern medicine. A deeper understanding of the pathogenesis…”
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Social huddling and physiological thermoregulation are related to melanism in the nocturnal barn owl by Dreiss, Amélie N, Séchaud, Robin, Béziers, Paul, Villain, Nicolas, Genoud, Michel, Almasi, Bettina, Jenni, Lukas, Roulin, Alexandre

“…Endothermic animals vary in their physiological ability to maintain a constant body temperature. Since melanin-based coloration is related to thermoregulation…”
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Validation study of "Santé-Cerveau", a digital tool for early cognitive changes identification by Lesoil, Constance, Bombois, Stéphanie, Guinebretiere, Octave, Houot, Marion, Bahrami, Mahsa, Levy, Marcel, Genthon, Rémy, Bozon, Frédérique, Jean-Marie, Heidy, Epelbaum, Stéphane, Foulon, Pierre, Villain, Nicolas, Dubois, Bruno

“…There is a need for a reliable, easy-to-use, widely available, and validated tool for timely cognitive impairment identification. We created a computerized…”
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Brain activity and functional coupling changes associated with self-reference effect during both encoding and retrieval by Morel, Nastassja, Villain, Nicolas, Rauchs, Géraldine, Gaubert, Malo, Piolino, Pascale, Landeau, Brigitte, Mézenge, Florence, Desgranges, Béatrice, Eustache, Francis, Chételat, Gaël

“…Information that is processed with reference to oneself, i.e. Self-Referential Processing (SRP), is generally associated with better remembering compared to…”
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Long-term effect of apomorphine infusion in advanced Parkinson’s disease: a real-life study by Meira, Bruna, Degos, Bertrand, Corsetti, Elise, Doulazmi, Mohamed, Berthelot, Emeline, Virbel-Fleischman, Clara, Dodet, Pauline, Méneret, Aurélie, Mariani, Louise-Laure, Delorme, Cécile, Cormier-Dequaire, Florence, Bendetowicz, David, Villain, Nicolas, Tarrano, Clément, Mantisi, Lise, Letrillart, Hélène, Louapre, Céline, McGovern, Eavan, Worbe, Yulia, Grabli, David, Vidailhet, Marie, Hainque, Elodie, Roze, Emmanuel

“…Long-term effects of continuous subcutaneous apomorphine infusion (CSAI) on health-related quality of life (HRQoL) and predictors of CSAI discontinuation are…”
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US Food and Drug Administration Approval of Aducanumab-Is Amyloid Load a Valid Surrogate End Point for Alzheimer Disease Clinical Trials? by Planche, Vincent, Villain, Nicolas

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Advocating for Demonstration of Disease Modification-Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly? by Planche, Vincent, Villain, Nicolas

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Posterior cortical atrophy: new insights into treatments and biomarkers for Alzheimer's disease by Bejanin, Alexandre, Villain, Nicolas

“…Conventional clinical trials are not usually designed to accommodate participants with posterior cortical atrophy, because inclusion criteria and outcomes are…”
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What is Alzheimer's disease? An analysis of nosological perspectives from the 20th and 21st centuries by Villain, Nicolas, Michalon, Robin

“…Background Recent US proposals suggest defining Alzheimer's disease (AD) based on β‐amyloidosis alone. This sparked debates that echoed historical ones about…”
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A Simple Way to Improve Anatomical Mapping of Functional Brain Imaging by Villain, Nicolas, Landeau, Brigitte, Groussard, Mathilde, Mevel, Katell, Fouquet, Marine, Dayan, Jacques, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël

“…ABSTRACT BACKGROUND AND PURPOSE Advances in functional neuroimaging studies have led to the need for improved anatomical precision to face with more and more…”
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Le comportement du porc domestique (Sus scrofa domesticus) by TALLET, Céline, AHLOY-DALLAIRE, Jamie, CHEBAHI, Azzedine, CLOUARD, Caroline, COURBOULAY, Valérie, GOUMON, Sébastien, LANTHONY, Mathilde, VILLAIN, Nicolas

“…L’étude du comportement animal, ou éthologie, apporte des connaissances sur les animaux d’élevage depuis les années 1950. Si les études se sont focalisées dans…”
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Disentangling clinical and biological trajectories of neurodegenerative diseases by Villain, Nicolas, Planche, Vincent

“…In recent years, we have seen a shift towards defining sporadic neurodegenerative diseases as a biological continuum. Here, we discuss the risks associated…”
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What is Alzheimer's disease? An Analysis of Nosological Perspectives from the 20th and 21st Centuries Running title: History of Alzheimer's disease Nosology by Villain, Nicolas, Michalon, Robin

“…Background Recent US proposals suggest defining Alzheimer's disease (AD) based on β‐amyloidosis alone. This sparked debates that echoed historical ones about…”
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2024 AA criteria for Alzheimer's disease diagnosis: Mainly anchored at Aβ not tau by Moscoso, Alexis, Villain, Nicolas

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The Great Debate in Diagnosing Alzheimer Disease: More Than Just a β Test by Villain, Nicolas, Paretsky, Melissa S

“…The study by Bieger highlights the implications of differences between AD diagnostic guidelines. The findings confirming a benign prognosis in cognitively…”
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