Search Results - "Villafan‐Bernal, Jose Rafael"
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Earlier detection of gestational diabetes impacts on medication requirements, neonatal and maternal outcomes
Published in Diabetes, obesity & metabolism (01-08-2024)“…Aim Gestational diabetes (GD) is a global health concern with significant implications for maternal and neonatal outcomes. This study investigates the…”
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Plasma Levels of Free Fatty Acids in Women with Gestational Diabetes and Its Intrinsic and Extrinsic Determinants: Systematic Review and Meta-Analysis
Published in Journal of diabetes research (2019)“…Background. Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals…”
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Novel Ratio Soluble Fms-like Tyrosine Kinase-1/Angiotensin-II (sFlt-1/ANG-II) in Pregnant Women Is Associated with Critical Illness in COVID-19
Published in Viruses (23-09-2021)“…In healthy pregnancies, components of the Renin-Angiotensin system (RAS) are present in the placental villi and contribute to invasion, migration, and…”
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Osteocalcin‑GPRC6A: An update of its clinical and biological multi‑organic interactions (Review)
Published in Molecular medicine reports (01-01-2019)“…Osteocalcin is no longer regarded as a molecule exclusive to bone remodeling and osteogenesis, but as a hormone with manifold functions. The discovery of the…”
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Impact of Protease Inhibitor-Based Highly Active Antiretroviral Therapy on Fetal Subcutaneous Fat Tissue in HIV-Pregnant Women in a Middle-Income Country
Published in Viruses (20-12-2023)“…HIV infection continues to be a global public health challenge, affecting approximately 1.7 million reproductive-aged women. Protease inhibitor-based highly…”
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Plasma Total Antioxidant Capacity and Carbonylated Proteins Are Increased in Pregnant Women with Severe COVID-19
Published in Viruses (30-03-2022)“…Oxidative stress (OS) induced by SARS-CoV-2 infection may play an important role in COVID-19 complications. However, information on oxidative damage in…”
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Maternal Death by COVID-19 Associated with Elevated Troponin T Levels
Published in Viruses (28-01-2022)“…Cardiomyocyte injury and troponin T elevation has been reported within COVID-19 patients and are associated with a worse prognosis. Limited data report this…”
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Exome Sequence Data of Eight SLC Transporters Reveal That SLC22A1 and SLC22A3 Variants Alter Metformin Pharmacokinetics and Glycemic Control
Published in Pharmaceuticals (Basel, Switzerland) (17-10-2024)“…: Type 2 diabetes (T2D) is one of the leading causes of mortality and is a public health challenge worldwide. Metformin is the first-choice treatment for T2D;…”
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Unraveling Signatures of Local Adaptation among Indigenous Groups from Mexico
Published in Genes (30-11-2022)“…Few studies have addressed how selective pressures have shaped the genetic structure of the current Native American populations, and they have mostly limited…”
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Effects of maternal characteristics and medical history on first trimester biomarkers for preeclampsia
Published in Frontiers in medicine (24-01-2023)“…To identify and quantify the effects of maternal characteristics and medical history on the distribution of Placental Growth Factor (PlGF), mean arterial…”
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Total Antioxidant Capacity in Obese and Non-Obese Subjects and Its Association with Anthropo-Metabolic Markers: Systematic Review and Meta-Analysis
Published in Antioxidants (28-07-2023)“…The total antioxidant capacity (TAC) has been related to the development of and complications associated with chronic diseases, but its importance during…”
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sFlt-1 Is an Independent Predictor of Adverse Maternal Outcomes in Women With SARS-CoV-2 Infection and Hypertensive Disorders of Pregnancy
Published in Frontiers in medicine (09-05-2022)“…Preeclampsia (PE) and COVID-19 share a common vascular-endothelial physiopathological pathway that may aggravate or worsen women's outcomes when both coexist…”
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CFTR pathogenic variants spectrum in a cohort of Mexican patients with cystic fibrosis
Published in Heliyon (15-04-2024)“…Molecular diagnosis of cystic fibrosis (CF) is challenging in Mexico due to the population's high genetic heterogeneity. To date, 46 pathogenic variants (PVs)…”
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Osteocalcin serum concentrations and markers of energetic metabolism in pediatric patients. Systematic review and metanalysis
Published in Frontiers in pediatrics (12-01-2023)“…Osteocalcin plays a role in glucose metabolism in mice, but its relevance in human energetic metabolism is controversial. Its relationship with markers of…”
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Association of PADI2 and PADI4 polymorphisms in COVID-19 host severity and non-survival
Published in Heliyon (30-03-2024)“…Enzymes of the peptidylarginine deiminase family (PADs) play a relevant role in the pathogenesis of COVID-19. However, the association of single nucleotide…”
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Extended low oxygen transmissibility contact lens use induces alterations in the concentration of proinflammatory cytokines, enzymes and electrolytes in tear fluid
Published in Experimental and therapeutic medicine (01-05-2018)“…Prolonged and continuous use of contact lenses for as long as 3 or 4 weeks is common in Mexico due to the low socioeconomic status, poor patient education and…”
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A Cut-Point Value of Uncarboxylated to Carboxylated Index Is Associated With Glycemic Status Markers in Type 2 Diabetes
Published in Journal of investigative medicine (01-01-2014)“…BackgroundThe uncarboxylated osteocalcin (ucOC) has been described as a regulator of glucose metabolism in mice, and it is decreased in human type 2 diabetes…”
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Molecular profiling of a simple rat model of open tibial fractures with hematoma and periosteum disruption
Published in Experimental and therapeutic medicine (01-11-2016)“…Bone fractures are a worldwide public health concern. Therefore, improving understanding of the bone healing process at a molecular level, which could lead to…”
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Influential Serum Kinases and Phosphatases in Preeclampsia—Systematic Review and Metanalysis
Published in International journal of molecular sciences (01-08-2023)“…The early identification of women with an increased risk of preeclampsia (PE) is desirable, but apart from soluble fms-like tyrosine kinase-1 (sFlt-1), few…”
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Influential Serum Kinases (Non-sFlt-1) and Phosphatases in Preeclampsia—Systemic Review and Metanalysis
Published in International journal of molecular sciences (16-08-2023)“…The early identification of women with an increased risk of preeclampsia (PE) is desirable, but apart from soluble fms-like tyrosine kinase-1 (sFlt-1), few…”
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