Search Results - "Villacian, Jorge"
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Matching diagnostics development to clinical need: Target product profile development for a point of care test for community-acquired lower respiratory tract infection
Published in PloS one (01-08-2018)“…Point of care tests (POCTs) are increasingly being promoted for guiding the primary medical care of community acquired lower respiratory tract infections…”
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Broad Phenotypic Cross-Resistance to Elvitegravir in HIV-Infected Patients Failing on Raltegravir-Containing Regimens
Published in Antimicrobial Agents and Chemotherapy (01-06-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts
Published in Emerging infectious diseases (01-06-2003)“…Severe acute respiratory syndrome (SARS) is an emerging viral infectious disease. One of the largest outbreaks of SARS to date began in Singapore in March…”
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Ritonavir-Boosted Tipranavir Demonstrates Superior Efficacy to Ritonavir-Boosted Protease Inhibitors in Treatment-Experienced HIV-Infected Patients: 24-Week Results of the RESIST-2 Trial
Published in Clinical infectious diseases (15-11-2006)“…Background. Tipranavir, a novel protease inhibitor, has demonstrated antiviral activity against protease inhibitor—resistant human immunodeficiency virus type…”
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Severe acute respiratory syndrome: lessons from Singapore
Published in Emerging infectious diseases (01-10-2003)“…An outbreak of severe acute respiratory syndrome (SARS) occurred in Singapore in March 2003. To illustrate the problems in diagnosing and containing SARS in…”
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In-flight transmission of severe acute respiratory syndrome (SARS): A case report
Published in Journal of travel medicine (01-09-2003)Get full text
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The effect of infection with Mycobacterium tuberculosis on T-cell activation and proliferation in patients with and without HIV co-infection
Published in The Journal of infection (01-12-2005)“…Tuberculosis is the most common opportunistic infection in HIV-infected people living in developing countries and is believed to accelerate the progression of…”
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Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections. A systematic review and meta-analysis
Published in Clinical microbiology and infection (01-01-2022)“…Point-of-care tests could be essential in differentiating bacterial and viral acute community-acquired lower respiratory tract infections and driving…”
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2659. Substantially Elevated Influenza Risk in Vaccinated Immunocompromised Adults and High-Risk Patients Relative to All Vaccinated
Published in Open forum infectious diseases (27-11-2023)“…Abstract Background Annual influenza vaccine is universally recommended for high-risk adults, but effectiveness varies between 19-60% in the general population…”
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Feasibility of wearable sensor signals and self-reported symptoms to prompt at-home testing for acute respiratory viruses in the USA (DETECT-AHEAD): a decentralised, randomised controlled trial
Published in The Lancet. Digital health (01-08-2024)“…Early identification of an acute respiratory infection is important for reducing transmission and enabling earlier therapeutic intervention. We aimed to…”
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Development and performance of conventional HIV-1 phenotyping (Antivirogram®) and genotype-based calculated phenotyping assay (virco®TYPE HIV-1) on protease and reverse transcriptase genes to evaluate drug resistance
Published in Intervirology (01-01-2012)“…A wide array of monitoring tests is commercially available to gauge HIV-1 disease progression and the overall health status of an HIV-1-infected patient. Viral…”
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Performance of a Population-Based HIV-1 Tropism Phenotypic Assay and Correlation With V3 Genotypic Prediction Tools in Recent HIV-1 Seroconverters
Published in Journal of acquired immune deficiency syndromes (1999) (01-07-2008)“…Pure X4 and X4R5 dual-tropic viruses may be recognized in approximately 15% of drug-naive HIV-1-positive patients. CCR5 antagonists are active against R5…”
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Phenotypic impact of resistance mutations on etravirine susceptibility in HIV patients with prior failure to nonnucleoside analogues
Published in AIDS (London) (12-11-2008)“…The phenotypic impact on etravirine susceptibility was examined in plasma specimens from 40 nonnucleoside reverse transcriptase inhibitor-experienced HIV…”
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HIV Drug Resistance Tests: An Update on Methods for Calculating Phenotypic Fold Change from a Viral Genotype
Published in Clinical infectious diseases (01-03-2009)Get full text
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Clinical cut-offs for HIV-1 phenotypic resistance estimates: Update based on recent pivotal clinical trial data and a revised approach to viral mixtures
Published in Journal of virological methods (01-12-2009)“…The clinical utility of HIV-1 resistance testing is dependent upon accurate interpretation and application of results. The development of clinical cut-offs…”
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Impact of baseline protease genotype and phenotype on the response to darunavir outside clinical trials
Published in Journal of antimicrobial chemotherapy (01-12-2007)Get full text
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HIV-1 genotyping of the protease-reverse transcriptase and integrase genes to detect mutations that confer antiretroviral resistance
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Major advances in antiretroviral (ARV) therapy during the last decade have made HIV-1 infections a chronic, manageable disease. In spite of these significant…”
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Selection of L74V mutation in reverse transcriptase of HIV-1 subtype D by a tenofovir DF-lamivudine based regimen
Published in AIDS (London) (30-11-2007)“…HIV-1 reverse transcriptase (RT) drug resistance mutations and their association with RT inhibitors selective pressure have been extensively described and…”
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HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries
Published in Acta dermatovenerologica Alpina, Panonica, et Adriatica (01-12-2010)“…Information about patterns of HIV-1 drug resistance among treatment-exposed patients is crucial for the development of novel effective drugs. Currently no…”
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Prevention of infections in solid organ transplant recipients
Published in Transplant infectious disease (01-03-1999)“…: Solid organ transplantation has become an important therapeutic option for multiple chronic diseases. With the advent of newer and potent immunosuppressive…”
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