Search Results - "Villa‐Tanaca, Lourdes"
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Point mutations in Candida glabrata 3-hydroxy-3-methylglutaryl-coenzyme A reductase (CgHMGR) decrease enzymatic activity and substrate/inhibitor affinity
Published in Scientific reports (21-10-2021)“…3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) is a crucial enzyme in the ergosterol biosynthesis pathway. The aim of this study was to obtain, purify,…”
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Dibutyltin(IV) Complexes Derived from L-DOPA: Synthesis, Molecular Docking, Cytotoxic and Antifungal Activity
Published in Chemical & pharmaceutical bulletin (01-12-2018)“…A series of organotin(IV) complexes was herein prepared and characterized. A one-pot synthetic strategy afforded reasonable to high yields, depending on the…”
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3
Phylogenetic Position of Geosmithia spp. (Hypocreales) Living in Juniperus spp. Forests (Cupressaceae) with Bark Beetles of Phloeosinus spp. (Scolytinae) from the Northeast of Mexico
Published in Forests (01-11-2020)“…Geosmithia members are mitosporic filamentous fungi commonly recorded and isolated from bark beetles of the Scolytinae subfamily and their respective host’s…”
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4
Pyrrole-Based Enaminones as Building Blocks for the Synthesis of Indolizines and Pyrrolo[1,2-a]pyrazines Showing Potent Antifungal Activity
Published in Molecules (Basel, Switzerland) (01-10-2023)“…As a new approach, pyrrolo[1,2-a]pyrazines were synthesized through the cyclization of 2-formylpyrrole-based enaminones in the presence of ammonium acetate…”
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Genomic Insights into Pseudomonas protegens E1BL2 from Giant Jala Maize: A Novel Bioresource for Sustainable Agriculture and Efficient Management of Fungal Phytopathogens
Published in International journal of molecular sciences (01-09-2024)“…The relationships between plants and bacteria are essential in agroecosystems and bioinoculant development. The leaf endophytic E1BL2 was previously isolated…”
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Synthesis, In Silico Study, and In Vitro Antifungal Activity of New 5-(1,3-Diphenyl-1 H -Pyrazol-4-yl)-4-Tosyl-4,5-Dihydrooxazoles
Published in International journal of molecular sciences (07-05-2024)“…The increase in multi-drug resistant strains has caused a sharp rise in life-threatening fungal infections in immunosuppressed patients, including those with…”
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Inhibitors of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Decrease the Growth, Ergosterol Synthesis and Generation of petite Mutants in Candida glabrata and Candida albicans
Published in International journal of molecular sciences (01-12-2023)“…and , the most frequently isolated candidiasis species in the world, have developed mechanisms of resistance to treatment with azoles. Among the clinically…”
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8
Promotion of the growth and yield of Zea mays by synthetic microbial communities from Jala maize
Published in Frontiers in microbiology (19-05-2023)“…Plant growth-promoting bacteria (PGPB) are a source of nutrient supply, stimulate plant growth, and even act in the biocontrol of phytopathogens. However,…”
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Intracellular Aminopeptidase Activity Determination from the Fungus Sporisorium reilianum: Purification and Biochemical Characterization of psrAPEi Enzyme
Published in Current microbiology (01-03-2022)“…The aims of this study were to, first, determine the intracellular aminopeptidase activity (APEi) and second, purify and biochemically characterize one…”
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Interactions between the AraC/XylS-like transcriptional activator InvF of Salmonella Typhimurium, the RNA polymerase alpha subunit and the chaperone SicA
Published in Scientific reports (02-01-2024)“…Salmonella enterica serovar Typhimurium causes gastroenteritis and systemic infections in humans. For this bacterium the expression of a type III secretion…”
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Review and Current Perspectives on DNA Topoisomerase I and II Enzymes of Fungi as Study Models for the Development of New Antifungal Drugs
Published in Journal of fungi (Basel) (03-09-2024)“…Fungal infections represent a growing public health problem, mainly stemming from two phenomena. Firstly, certain diseases (e.g., AIDS and COVID-19) have…”
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Synthesis, Molecular Docking, and Antimycotic Evaluation of Some 3-Acyl Imidazo[1,2-a]pyrimidines
Published in Molecules (Basel, Switzerland) (07-03-2018)“…A series of 3-benzoyl imidazo[1,2- ]pyrimidines, obtained from -heteroarylformamidines in good yields, was tested in silico and in vitro for binding and…”
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13
Molecular Recognition of Citroflavonoids Naringin and Naringenin at the Active Site of the HMG-CoA Reductase and DNA Topoisomerase Type II Enzymes of Candida spp. and Ustilago maydis
Published in Indian journal of microbiology (01-03-2022)“…Two agents from natural sources, citroflavonoids naringin and naringenin, can target enzymes in pathogenic yeasts responsible for hospital infections and crop…”
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Unlocking the hidden potential of Mexican teosinte seeds: revealing plant growth-promoting bacterial and fungal biocontrol agents
Published in Frontiers in plant science (04-10-2023)“…The bacterial component of plant holobiont maintains valuable interactions that contribute to plants' growth, adaptation, stress tolerance, and antagonism to…”
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Phylogeny, evolution, and potential ecological relationship of cytochrome CYP52 enzymes in Saccharomycetales yeasts
Published in Scientific reports (24-06-2020)“…Cytochrome P450s from the CYP52 family participate in the assimilation of alkanes and fatty acids in fungi. In this work, the evolutionary history of a set of…”
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16
Inferring the role of microorganisms in water kefir fermentations
Published in International journal of food science & technology (01-02-2017)“…Summary Water kefir is a slightly alcoholic, lactic and acetic beverage fermented by yeasts, lactic acid bacteria and acetic acid bacteria that are associated…”
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The Salmonella Typhimurium InvF-SicA complex is necessary for the transcription of sopB in the absence of the repressor H-NS
Published in PloS one (29-10-2020)“…Expression of virulence factors in non-typhoidal Salmonella enterica depends on a wide variety of general and specific transcriptional factors that act in…”
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Streptomyces albidoflavus Q antifungal metabolites inhibit the ergosterol biosynthesis pathway and yeast growth in fluconazole-resistant Candida glabrata : phylogenomic and metabolomic analyses
Published in Microbiology spectrum (01-10-2023)“…ABSTRACT There is an urgent need to develop new antifungals due to the increasing prevalence of multidrug-resistant fungal infections and the recent emergence…”
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Three-Component Synthesis of 2-Amino-3-cyano-4H-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing
Published in Pharmaceuticals (Basel, Switzerland) (30-10-2021)“…Chromenes are compounds that may be useful for inhibiting topoisomerase and cytochrome, enzymes involved in the growth of cancer and fungal cells,…”
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Comparative Genomics of the First Resistant Candida auris Strain Isolated in Mexico: Phylogenomic and Pan-Genomic Analysis and Mutations Associated with Antifungal Resistance
Published in Journal of fungi (Basel) (30-05-2024)“…is an emerging multidrug-resistant and opportunistic pathogenic yeast. Whole-genome sequencing analysis has defined five major clades, each from a distinct…”
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