Search Results - "Villa, Y."
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Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy
Published in The Journal of clinical investigation (01-08-2023)“…Entry of antigen-specific T cells into human tumors is critical for immunotherapy, but the underlying mechanisms are poorly understood. Here, we combined…”
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Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eliminates lung metastatic mouse osteosarcoma
Published in Molecular therapy. Oncolytics (24-09-2021)“…Solid cancers that metastasize to the lungs represent a major therapeutic challenge. Current treatment paradigms for lung metastases consist of radiation…”
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3
Determining the anisotropy and exchange parameters of polycrystalline spin-1 magnets
Published in New journal of physics (12-09-2019)“…Although low-dimensional S = 1 antiferromagnets remain of great interest, difficulty in obtaining high-quality single crystals of the newest materials hinders…”
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4
Interplay between poxviruses and the cellular ubiquitin/ubiquitin-like pathways
Published in FEBS letters (18-02-2009)“…Post-translational polypeptide tagging by conjugation with ubiquitin and ubiquitin-like (Ub/Ubl) molecules is a potent way to alter protein functions and/or…”
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5
Sphingolipids function as downstream effectors of a fungal PAQR
Published in Molecular pharmacology (01-04-2009)“…The Izh2p protein from Saccharomyces cerevisiae belongs to the newly characterized progestin and adipoQ receptor (PAQR) superfamily of receptors whose…”
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6
Phylogenetic and Preliminary Phenotypic Analysis of Yeast PAQR Receptors: Potential Antifungal Targets
Published in Journal of molecular evolution (01-10-2011)“…Proteins belonging to the P rogestin and A dipoQ R eceptor (PAQR) superfamily of membrane bound receptors are ubiquitously found in fungi. Nearly, all fungi…”
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Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies
Published in Viruses (22-03-2016)“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a curative potential for many hematologic malignancies and blood diseases. However, the…”
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Metalloregulation of Yeast Membrane Steroid Receptor Homologs
Published in Proceedings of the National Academy of Sciences - PNAS (13-04-2004)“…Zinc is an essential micronutrient that can also be toxic. An intricate mechanism exists in yeast that maintains cellular zinc within an optimal range. The…”
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Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor
Published in Molecular therapy. Oncolytics (17-03-2017)“…Allogeneic stem cell transplant-derived T cells have the potential to seek and eliminate sites of residual cancer that escaped primary therapy. Oncolytic…”
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10
Integral incident management system in primary care: Beyond patient safety
Published in Revista de calidad asistencial (01-11-2017)“…To describe an integral system of notification and management of incidents, created by the Primary Care Team of Guineueta, as well as the main results after 18…”
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Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series
Published in Cell (30-05-2019)“…Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time…”
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12
Methotrexate in chronic active ulcerative colitis: A double-blind, randomized, Israeli multicenter trial
Published in Gastroenterology (New York, N.Y. 1943) (01-05-1996)“…BACKGROUND & AIMS: Uncontrolled studies have suggested that methotrexate may be effective in patients with active ulcerative colitis. The aim of this study was…”
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13
Dissecting the regulation of yeast genes by the osmotin receptor
Published in Biochemical and biophysical research communications (19-09-2008)“…The Izh2p protein from Saccharomyces cerevisiae is a receptor for the plant antifungal protein, osmotin. Since Izh2p is conserved in fungi, understanding its…”
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14
Does severity of ischemic coronary disease correlate with erectile function?
Published in International journal of impotence research (01-09-1997)“…An association between diminution in the quality of male sexual function and ischemic coronary disease has been suggested. Patients with ischemic heart disease…”
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15
Common mutations in the familial Mediterranean fever gene associate with rapid progression to disability in non-Ashkenazi Jewish multiple sclerosis patients
Published in Genes and immunity (01-04-2003)“…Ancient founder mutations in the Mediterranean fever gene, MEFV, are associated with familial Mediterranean fever, a recessive, episodic, inflammatory disease…”
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CD133+CD34+ and CD133+CD38+ blood progenitor cells as predictors of platelet engraftment in patients undergoing autologous peripheral blood stem cell transplantation
Published in Transfusion and apheresis science (01-06-2012)“…Abstract Background Hematopoietic stem cells (HSC) have been characterized by CD34+ expression and an adequate dose of CD34+ cells is associated with a…”
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Ex Vivo Virotherapy with Myxoma Virus to Treat Cancer
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…Myxoma virus (MYXV) is a member of the Poxviridae family and the genus Leporipoxvirus. In nature MYXV tropism is restricted to lagomorphs, and is specifically…”
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Sistema integral de gestión de incidencias en atención primaria: más allá de la seguridad del paciente
Published in Revista de calidad asistencial (01-11-2017)“…Resumen Objetivo Describir un sistema integral de notificación y gestión de incidencias creado por el EAP Guineueta, así como sus principales resultados,…”
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19
Near-ideal molecule-based Haldane spin chain
Published in Physical review research (27-01-2020)“…The molecular coordination complex NiI_{2}(3,5-lut)_{4} [where (3,5-lut) = (3,5-lutidine) =(C_{7}H_{9}N)] has been synthesized and characterized by several…”
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Effects of current cigarette smoking on clinical course of Crohn's disease and ulcerative colitis
Published in Digestive diseases and sciences (01-08-2001)“…Cigarette smoking worsens Crohn's disease (CD) but ameliorates ulcerative colitis (UC). In Israel, where there is no epidemiological association of smoking…”
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