Search Results - "Villa, Vilmar"
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Mechanisms of Radiation Bystander and Non-Targeted Effects: Implications to Radiation Carcinogenesis and Radiotherapy
Published in Current radiopharmaceuticals (01-01-2018)“…Knowledge of radiobiology is of paramount importance to be able to grasp and have an in-depth understanding of the consequences of ionizing radiation. One of…”
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Radiation protection and mitigation potential of phenylbutyrate: delivered via oral administration
Published in International journal of radiation biology (02-09-2017)“…Purpose: Phenylbutyrate (PB), a histone deacetylase inhibitor (HDACi) has demonstrated radiation protection in both in vitro and in vivo models. Studies…”
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New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel
Published in Journal of radiation research (01-12-2002)“…New strategies for the prevention of radiation injuries are currently being explored with the ultimate aim of developing globally radioprotective, nontoxic…”
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Delta-Tocotrienol Protects Mice from Radiation-Induced Gastrointestinal Injury
Published in Radiation research (01-12-2013)“…We recently demonstrated that natural delta-tocotrienol (DT3) significantly enhanced survival in total-body irradiated (TBI) mice, and protected mouse bone…”
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Health Effects of Embedded Depleted Uranium
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Artifacts related to N-methyl- N-( tert-butyldimethylsilyl)trifluoroacetamide derivatization of citrulline revealed by gas chromatography–mass spectrometry using both electron and chemical ionization
Published in Journal of Chromatography A (13-08-2010)“…Derivatization with N-methyl- N-( tert-butyldimethylsilyl)trifluoroacetamide (MTBSTFA) was used for gas chromatography–mass spectrometry (GC–MS) analysis of…”
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Acute Toxicity of Subcutaneously Administered Vitamin E Isomers Delta- and Gamma-Tocotrienol in Mice
Published in International journal of toxicology (01-11-2014)“…The toxicity of parenterally administered vitamin E isomers, delta-tocotrienol (DT3) and gamma-tocotrienol (GT3), was evaluated in male and female CD2F1 mice…”
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Delta-Tocotrienol Protects Mice fromRadiation-Induced Gastrointestinal Injury
Published in Radiation research (01-12-2013)“…We recently demonstrated that natural delta-tocotrienol (DT3) significantly enhanced survival in total-body irradiated (TBI) mice, and protected mouse bone…”
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Application of Multivariate Modeling for Radiation Injury Assessment : A Proof of Concept
Published in Computational and mathematical methods in medicine (01-01-2014)“…Multivariate radiation injury estimation algorithms were formulated for estimating severe hematopoietic acute radiation syndrome (H-ARS) injury (i.e., response…”
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Depleted uranium–uranyl chloride induces apoptosis in mouse J774 macrophages
Published in Toxicology (Amsterdam) (30-09-2002)“…Depleted uranium entering the body as a result of inhalation or embedded fragments becomes associated to a great extent with macrophages. As part of our…”
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Molecular Specificity of 5-Androstenediol as a Systemic Radioprotectant in Mice
Published in Immunopharmacology and immunotoxicology (2005)“…We compared in vivo radioprotective efficacy of 5-androstenediol (5-AED) to that of ten other steroids: 17α-androstenediol, dehydroepiandrosterone,…”
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Hemoglobin Stimulates Mononuclear Leukocytes to Release Interleukin-8 and Tumor Necrosis Factor α
Published in Blood (01-11-1994)“…Incubation of human mononuclear leukocytes (MNL) with human stroma-free hemolysate (SFH), purified adult hemoglobin Ao (HbAo), and oxidized HbAo (METHb) caused…”
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Health effects of embedded depleted uranium
Published in Military medicine (01-02-2002)“…The health effects of embedded fragments of depleted uranium (DU) are being investigated to determine whether current surgical fragment-removal policies are…”
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New Strategies for the Prevention of Radiation Injury: Possible Implications for Countering Radiation Hazards of Long-term Space Travel
Published in JOURNAL OF RADIATION RESEARCH (01-12-2002)“…New strategies for the prevention of radiation injuries are currently being explored with the ultimate aim of developing globally radioprotective, nontoxic…”
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New Strategies for the Prevention of Radiation Injury
Published in Journal of radiation research (01-01-2002)“…New strategies for the prevention of radiation injuries are currently being explored with the ultimate aim of developing globally radioprotective, nontoxic…”
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Effects of anesthesia and vehicle injection on circulating blood elements in C3H/HeN male mice
Published in Contemporary topics in laboratory animal science (01-09-2004)“…The induction and maintenance of general anesthesia can lead to profound alterations of many organ systems, especially the cardiovascular, pulmonary, and…”
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Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood
Published in The Journal of laboratory and clinical medicine (01-03-2000)“…Isolated mononuclear leukocytes, when incubated with purified hemoglobin Ao (HbAo), release the proinflammatory cytokines interleukin-8 (IL-8) and tumor…”
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