Search Results - "Villa, Roberto Federico"

The treament of hyperglycemia in acute ischemic stroke with incretin-based drugs by Ferrari, Federica, Moretti, Antonio, Villa, Roberto Federico

“…[Display omitted] Stroke is a major cause of mortality and morbidity worldwide. Considerable experimental and clinical evidence suggests that both diabetes…”
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Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity by Ferrari, Federica, Moretti, Antonio, Villa, Roberto

“…Diabetes mellitus and associated chronic hyperglycemia enhance the risk of acute ischemic stroke and lead to worsened clinical outcome and increased mortality…”
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Post-stroke depression: Mechanisms and pharmacological treatment by Villa, Roberto Federico, Ferrari, Federica, Moretti, Antonio

“…Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively affects survivals' functional outcome, response to rehabilitation and…”
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Brain bioenergetics in chronic hypertension: Risk factor for acute ischemic stroke by Ferrari, Federica, Villa, Roberto Federico

“…[Display omitted] Chronic hypertension is one of the key modifiable risk factors for acute ischemic stroke, also contributing to determine greater neurological…”
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Incretin-based drugs as potential therapy for neurodegenerative diseases: current status and perspectives by Ferrari, Federica, Moretti, Antonio, Villa, Roberto Federico

“…Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the most frequent neurodegenerative disorders. Despite their pathophysiological and clinical…”
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Functional proteomics of adenosine triphosphatase system in the rat striatum during aging by Villa, Roberto Federico, Ferrari, Federica, Gorini, Antonella

“…The maximum rates of adenosine triphosphatase (ATPase) systems related to energy consumption were systematically evaluated in synaptic plasma membranes…”
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Effects of Chronic Hypertension on the Energy Metabolism of Cerebral Cortex Mitochondria in Normotensive and in Spontaneously Hypertensive Rats During Aging by Villa, Roberto Federico, Ferrari, Federica, Gorini, Antonella

“…In this study the subcellular modifications undergone by cerebral cortex mitochondrial metabolism in chronic hypertension during aging were evaluated. The…”
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Glutamate metabolism in cerebral mitochondria after ischemia and post‐ischemic recovery during aging: relationships with brain energy metabolism by Ferrari, Federica, Gorini, Antonella, Hoyer, Siegfried, Villa, Roberto Federico

“…Glutamate is involved in cerebral ischemic injury, but its role has not been completely clarified and studies are required to understand how to minimize its…”
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Mitochondrial energy metabolism of rat hippocampus after treatment with the antidepressants desipramine and fluoxetine by Villa, Roberto Federico, Ferrari, Federica, Bagini, Laura, Gorini, Antonella, Brunello, Nicoletta, Tascedda, Fabio

“…Alterations in mitochondrial functions have been hypothesized to participate in the pathogenesis of depression, because brain bioenergetic abnormalities have…”
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Functional proteomics of synaptic plasma membrane ATP-ases of rat hippocampus: Effect of l-acetylcarnitine and relationships with Dementia and Depression pathophysiology by Ferrari, Federica, Gorini, Antonella, Villa, Roberto Federico

“…Synaptic energy state and mitochondrial dysfunction are crucial factors in many brain pathologies. l-acetylcarnitine, a natural derivative of carnitine,…”
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Synaptic ATPases system of rat frontal cerebral cortex during aging by Ferrari, Federica, Viscardi, Paola, Gorini, Antonella, Villa, Roberto Federico

“…•Energy-consuming ATP-ases were studied during aging.•Acetylcholinesterase (AChE) activity was assayed as well.•Enzymes were evaluated on synaptic plasma…”
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Effect of desipramine and fluoxetine on energy metabolism of cerebral mitochondria by Villa, Roberto Federico, Ferrari, Federica, Gorini, Antonella, Brunello, Nicoletta, Tascedda, Fabio

“…Graphical abstract…”
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Clonidine and Brain Mitochondrial Energy Metabolism: Pharmacodynamic Insights Beyond Receptorial Effects by Villa, Roberto Federico, Gorini, Antonella, Ferrari, Federica

“…Clonidine is an anti-hypertensive drug that inhibits the release of norepinephrine from pre-synaptic terminals binding to pre-synaptic α 2 -adrenoreceptors…”
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Effect of CDP-choline on age-dependent modifications of energy- and glutamate-linked enzyme activities in synaptic and non-synaptic mitochondria from rat cerebral cortex by Villa, Roberto Federico, Ferrari, Federica, Gorini, Antonella

“…► CDP-choline is a neuroprotectant and memory enhancing drug in age-related brain diseases. ► The drug modifies molecular and neurochemical parameters related…”
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Energy Metabolism of Synaptosomes from Different Neuronal Systems of Rat Cerebellum During Aging: A Functional Proteomic Characterization by Ferrari, Federica, Gorini, Antonella, Villa, Roberto Federico

“…Functional proteomics was used to characterize age-related changes in energy metabolism of different neuronal pathways within the cerebellar cortex of Wistar…”
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Energy metabolism of cerebral mitochondria during aging, ischemia and post-ischemic recovery assessed by functional proteomics of enzymes by Villa, Roberto Federico, Gorini, Antonella, Ferrari, Federica, Hoyer, Siegfried

“…•Aging and ischemia impair brain bioenergetics that remains altered with reperfusion.•Complete ischemia (CCI) and recovery (R) up to 96h during aging was…”
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Effect of In Vivo l-Acetylcarnitine Administration on ATP-ases Enzyme Systems of Synaptic Plasma Membranes from Rat Cerebral Cortex by Villa, Roberto Federico, Ferrari, Federica, Gorini, Antonella

“…The maximum rates ( V max ) of some enzymatic activities related to energy consumption (ATP-ases) were evaluated in two types of synaptic plasma membranes…”
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Effect of Ageing and Ischemia on Enzymatic Activities Linked to Krebs’ Cycle, Electron Transfer Chain, Glutamate and Aminoacids Metabolism of Free and Intrasynaptic Mitochondria of Cerebral Cortex by Villa, Roberto Federico, Gorini, Antonella, Hoyer, Siegfried

“…The effect of ageing and the relationships between the catalytic properties of enzymes linked to Krebs’ cycle, electron transfer chain, glutamate and aminoacid…”
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Natural distribution and occurrence of coenzyme Q homologues by Battino, M, Ferri, E, Gorini, A, Villa, R F, Rodriguez Huertas, J F, Fiorella, P, Genova, M L, Lenaz, G, Marchetti, M

“…The knowledge of coenzyme Q levels in tissues, organs, and subcellular compartments is of outstanding interest. A wide amount of data regarding coenzyme Q…”
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unctional proteomics of adenosine triphosphatase system in the rat striatum during aging by Roberto Federico Villa Federica Ferrari Antonella Gorini

“…The maximum rates of adenosine triphosphatase （ATPase） systems related to energy consumption were systematically evaluated in synaptic plasma membranes…”
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