Search Results - "Vilim, Ferdinand S"
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Peptide Cotransmitters as Dynamic, Intrinsic Modulators of Network Activity
Published in Frontiers in neural circuits (02-10-2018)“…Neurons can contain both neuropeptides and "classic" small molecule transmitters. Much progress has been made in studies designed to determine the functional…”
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Multifaceted Expression of Peptidergic Modulation in the Feeding System of Aplysia
Published in ACS chemical neuroscience (15-08-2018)“…Neuropeptides are present in species throughout the animal kingdom and generally exert actions that are distinct from those of small molecule transmitters. It…”
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3
Urotensin II in invertebrates: from structure to function in Aplysia californica
Published in PloS one (08-11-2012)“…Neuropeptides are ancient signaling molecules that are involved in many aspects of organism homeostasis and function. Urotensin II (UII), a peptide with a…”
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Aplysia Locomotion: Network and Behavioral Actions of GdFFD, a D-Amino Acid-Containing Neuropeptide
Published in PloS one (21-01-2016)“…One emerging principle is that neuromodulators, such as neuropeptides, regulate multiple behaviors, particularly motivated behaviors, e.g., feeding and…”
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5
Neural Analog of Arousal: Persistent Conditional Activation of a Feeding Modulator by Serotonergic Initiators of Locomotion
Published in The Journal of neuroscience (19-11-2008)“…We investigated how a neural analog of a form of arousal induced by a mildly noxious stimulus can promote two antagonistic responses, locomotion and feeding…”
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6
Characterization of GdFFD, a d-Amino Acid-containing Neuropeptide That Functions as an Extrinsic Modulator of the Aplysia Feeding Circuit
Published in The Journal of biological chemistry (15-11-2013)“…During eukaryotic translation, peptides/proteins are created using l-amino acids. However, a d-amino acid-containing peptide (DAACP) can be produced through…”
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Discovery of leucokinin-like neuropeptides that modulate a specific parameter of feeding motor programs in the molluscan model, Aplysia
Published in The Journal of biological chemistry (17-11-2017)“…A better understanding of neuromodulation in a behavioral system requires identification of active modulatory transmitters. Here, we used identifiable neurons…”
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Complementary interactions between command-like interneurons that function to activate and specify motor programs
Published in The Journal of neuroscience (07-05-2014)“…Motor activity is often initiated by a population of command-like interneurons. Command-like interneurons that reliably drive programs have received the most…”
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Feedforward compensation mediated by the central and peripheral actions of a single neuropeptide discovered using representational difference analysis
Published in The Journal of neuroscience (08-12-2010)“…Compensatory mechanisms are often used to achieve stability by reducing variance, which can be accomplished via negative feedback during homeostatic…”
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Functional Characterization of a Vesicular Glutamate Transporter in an Interneuron That Makes Excitatory and Inhibitory Synaptic Connections in a Molluscan Neural Circuit
Published in The Journal of neuroscience (17-06-2015)“…Understanding circuit function requires the characterization of component neurons and their neurotransmitters. Previous work on radula protraction in the…”
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Newly Identified Aplysia SPTR-Gene Family-Derived Peptides: Localization and Function
Published in ACS chemical neuroscience (15-08-2018)“…When individual neurons in a circuit contain multiple neuropeptides, these peptides can target different sets of follower neurons. This endows the circuit with…”
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12
Composite modulatory feedforward loop contributes to the establishment of a network state
Published in Journal of neurophysiology (01-04-2010)“…Feedforward loops (FFLs) are one of many network motifs identified in a variety of complex networks, but their functional role in neural networks is not well…”
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13
From Hunger to Satiety: Reconfiguration of a Feeding Network by Aplysia Neuropeptide Y
Published in The Journal of neuroscience (28-03-2007)“…A shift in motivational state often produces behavioral change, but the underlying mechanisms are poorly understood. In the marine mollusc, Aplysia…”
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Distinct Mechanisms Produce Functionally Complementary Actions of Neuropeptides That Are Structurally Related But Derived from Different Precursors
Published in The Journal of neuroscience (06-01-2010)“…Many bioactive neuropeptides containing RFamide at their C terminus have been described in both invertebrates and vertebrates. To obtain insight into the…”
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Analysis of human neuropeptide FF gene expression
Published in Journal of neurochemistry (01-09-2002)“…As an initial step to study the function of the gene encoding the human neuropeptide FF (NPFF), we cloned a 4.7‐kb sequence from the promoter region. Primer…”
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Interneuronal and Peptidergic Control of Motor Pattern Switching in Aplysia
Published in Journal of neurophysiology (01-01-2002)“…Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029 Morgan, Peter T., Jian Jing, Ferdinand S. Vilim, and…”
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Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli
Published in Molecular pharmacology (01-05-1999)“…Neuropeptides FF (NPFF), AF (NPAF), and SF (NPSF) are homologous amidated peptides that were originally identified on the basis of similarity to the molluscan…”
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Concerted GABAergic Actions of Aplysia Feeding Interneurons in Motor Program Specification
Published in The Journal of neuroscience (15-06-2003)“…GABAergic inhibitory interneurons regulate the activity of diverse types of neural networks, but the specific roles of these interneurons in motor control are…”
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Identification of a New Neuropeptide Precursor Reveals a Novel Source of Extrinsic Modulation in the Feeding System of Aplysia
Published in The Journal of neuroscience (19-10-2005)“…The Aplysia feeding system is advantageous for investigating the role of neuropeptides in behavioral plasticity. One family of Aplysia neuropeptides is the…”
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Insulin Prohormone Processing, Distribution, and Relation to Metabolism in Aplysia californica
Published in The Journal of neuroscience (15-09-1999)“…The first Aplysia californica insulin gene is characterized and its proteolytic processing from prohormone to final peptides elucidated using a combination of…”
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