Search Results - "Vilfan, Gregor"
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Permeability of a novel beta-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro
Published in Journal of pharmacy and pharmacology (01-09-2009)“…LK-157 is a novel 10-ethylidene tricyclic carbapenem that resembles the structure of the broad-spectrum antibiotic sanfetrinem and acts as a potent inactivator…”
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Permeability of a novel β-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro
Published in Journal of pharmacy and pharmacology (01-09-2009)“…Objectives LK‐157 is a novel 10‐ethylidene tricyclic carbapenem that resembles the structure of the broad‐spectrum antibiotic sanfetrinem and acts as a potent…”
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Journal Article -
3
4-Substituted Trinems as Broad Spectrum β-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity
Published in Journal of medicinal chemistry (23-08-2007)“…A wide variety of pathogens have acquired antimicrobial resistance as an inevitable evolutionary response to the extensive use of antibacterial agents. In…”
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Journal Article