Search Results - "Vilariño, Marcela"

Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts by Bogliotti, Yanina Soledad, Wu, Jun, Vilarino, Marcela, Okamura, Daiji, Soto, Delia Alba, Zhong, Cuiqing, Sakurai, Masahiro, Sampaio, Rafael Vilar, Suzuki, Keiichiro, Belmonte, Juan Carlos Izpisua, Ross, Pablo Juan

“…Embryonic stem cells (ESCs) are derived from the inner cell mass of preimplantation blastocysts. From agricultural and biomedical perspectives, the derivation…”
Get full text

Interspecies Chimerism with Mammalian Pluripotent Stem Cells by Wu, Jun, Platero-Luengo, Aida, Sakurai, Masahiro, Sugawara, Atsushi, Gil, Maria Antonia, Yamauchi, Takayoshi, Suzuki, Keiichiro, Bogliotti, Yanina Soledad, Cuello, Cristina, Morales Valencia, Mariana, Okumura, Daiji, Luo, Jingping, Vilariño, Marcela, Parrilla, Inmaculada, Soto, Delia Alba, Martinez, Cristina A., Hishida, Tomoaki, Sánchez-Bautista, Sonia, Martinez-Martinez, M. Llanos, Wang, Huili, Nohalez, Alicia, Aizawa, Emi, Martinez-Redondo, Paloma, Ocampo, Alejandro, Reddy, Pradeep, Roca, Jordi, Maga, Elizabeth A., Esteban, Concepcion Rodriguez, Berggren, W. Travis, Nuñez Delicado, Estrella, Lajara, Jeronimo, Guillen, Isabel, Guillen, Pedro, Campistol, Josep M., Martinez, Emilio A., Ross, Pablo Juan, Izpisua Belmonte, Juan Carlos

“…Interspecies blastocyst complementation enables organ-specific enrichment of xenogenic pluripotent stem cell (PSC) derivatives. Here, we establish a versatile…”
Get full text

CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep by Vilarino, Marcela, Rashid, Sheikh Tamir, Suchy, Fabian Patrik, McNabb, Bret Roberts, van der Meulen, Talitha, Fine, Eli J., Ahsan, Syed Daniyal, Mursaliyev, Nurlybek, Sebastiano, Vittorio, Diab, Santiago Sain, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo J.

“…One of the ultimate goals of regenerative medicine is the generation of patient-specific organs from pluripotent stem cells (PSCs). Sheep are potential hosts…”
Get full text

Derivation of sheep embryonic stem cells under optimized conditions by Vilarino, Marcela, Alba Soto, Delia, Soledad Bogliotti, Yanina, Yu, Leqian, Zhang, Yanli, Wang, Chunsheng, Paulson, Erika, Zhong, Cuiqing, Jin, Miaohan, Carlos Izpisua Belmonte, Juan, Wu, Jun, Juan Ross, Pablo

“…Until recently, it has been difficult to derive and maintain stable embryonic stem cells lines from livestock species. Sheep ESCs with characteristics similar…”
Get full text

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs by Wu, Jun, Vilarino, Marcela, Suzuki, Keiichiro, Okamura, Daiji, Bogliotti, Yanina Soledad, Park, Insung, Rowe, Joan, McNabb, Bret, Ross, Pablo Juan, Belmonte, Juan Carlos Izpisua

“…Genome editing using programmable nucleases has revolutionized biomedical research. CRISPR-Cas9 mediated zygote genome editing enables high efficient…”
Get full text

Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep by Vilarino, Marcela, Suchy, Fabian Patrik, Rashid, Sheikh Tamir, Lindsay, Helen, Reyes, Juan, McNabb, Bret Roberts, van der Meulen, Talitha, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo Juan

“…The production of knock-out (KO) livestock models is both expensive and time consuming due to their long gestational interval and low number of offspring. One…”
Get full text

Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos by Chung, Nhi, Bogliotti, Yanina S., Ding, Wei, Vilarino, Marcela, Takahashi, Kazuki, Chitwood, James L., Schultz, Richard M., Ross, Pablo J.

“…The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental…”
Get full text

Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep by Vilarino, Marcela, Rashid, Sheikh Tamir, Suchy, Fabian Patrik, McNabb, Bret Roberts, van der Meulen, Talitha, Fine, Eli J., Ahsan, Syed Daniyal, Mursaliyev, Nurlybek, Sebastiano, Vittorio, Diab, Santiago Sain, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo J.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

CRISPR editing validation, immunostaining and DNA sequencing of individual fixed bovine embryos by Daigneault, Bradford W, Vilarino, Marcela, Rajput, Sandeep K, Frum, Tristan, Smith, George W, Ross, Pablo J

“…CRISPR technologies used for mammalian embryology have wide implications from basic research to applications in agriculture and biomedicine. Confirmation of…”
Get full text

Social dominance of female dairy goats and response to oestrous synchronisation and superovulatory treatments by Ungerfeld, Rodolfo, González-Pensado, Silvana, Dago, Ana Laura, Vilariño, Marcela, Menchaca, Alejo

“…Two experiments were performed to determine if there is a relation between the goat's hierarchical position, and (1) the conception rate and litter size…”
Get full text

Livestock Gene Editing by One-step Embryo Manipulation by Navarro-Serna, Sergio, Vilarino, Marcela, Park, Insung, Gadea, Joaquin, Ross, Pablo Juan

“…The breakthrough and rapid advance of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) technology has…”
Get full text

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes by Bogliotti, Yanina S, Vilarino, Marcela, Ross, Pablo J

“…Cytoplasmic microinjection into one-cell embryos is a very powerful technique. As an example, it enables the delivery of genome editing tools that can create…”
Get full text

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes by Bogliotti, Yanina S., Vilarino, Marcela, Ross, Pablo J.

Get full text

Abstract 6548: Bioinformatic characterization of dendritic and T cell subpopulations in the tumor microenvironment across different cancer types by single-cell RNA-Seq analysis by Mahmoud, Yamil D., Rego, Natalia, Vilarino, Marcela, Veigas, Florencia, Girotti, Maria R., Saez, Juan M. Perez, Rabinovich, Gabriel A., Hill, Marcelo

“…Abstract Although the development of single-cell RNAseq (scRNAseq) has improved the knowledge of the tumor microenvironment (TME), there is not a clear…”
Get full text

Gene Editing, Stem Cells and Chimeras in Sheep Embryos by Vilarino Pereda, Marcela

“…Genome editing has become the most used tool to produce genetically engineered animals. Specifically in livestock species, the CRISPR/Cas9 system has allowed…”
Get full text