Search Results - "Vilardo, P G"

Thiol/Disulfide Interconversion in Bovine Lens Aldose Reductase Induced by Intermediates of Glutathione Turnover by Vilardo, Pier Giuseppe, Scaloni, Andrea, Amodeo, Pietro, Barsotti, Catia, Cecconi, Ilaria, Cappiello, Mario, Lopez Mendez, Blanca, Rullo, Rosario, Dal Monte, Massimo, Del Corso, Antonella, Mura, Umberto

“…The effectiveness of cysteine and cysteinylglycine to act as protein thiolating agents was investigated using bovine lens aldose reductase (ALR2) as the…”
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A New Approach Against Sugar Cataract Through Aldose Reductase Inhibitors by BANDITELLI, STEFANIA, BOLDRINI, ENRICO, VILARDO, PIER GIUSEPPE, CECCONI, ILARIA, CAPPIELLO, MARIO, DAL MONTE, MASSIMO, MARINI, ISABELLA, DEL CORSO, ANTONELLA, MURA, UMBERTO

“…Aldose reductase inhibition is one of the therapeutic strategies that has been proposed to prevent or ameliorate long term diabetic complications including…”
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Thiol Disulfide Exchange Modulates the Activity of Aldose Reductase in Intact Bovine Lens as a Response to Oxidative Stress by Cappiello, Mario, Vilardo, Pier Giuseppe, Micheli, Vanna, Jacomelli, Gabriella, Banditelli, Stefania, Leverenz, Victor, Giblin, Frank J, Corso, Antonella Del, Mura, Umberto

“…The reversibility of S-thiolation of aldose reductase was shown in intact bovine lens subjected to oxidative stress. The glutathione modified aldose reductase…”
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Signalling potential and protein modifying ability of physiological thiols by Mura, U., Cappiello, M., Vilardo, P. G., Cecconi, I., Dal Monte, M., Del Corso, A.

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Kinetics of human thrombin inhibition by two novel peptide inhibitors (Hirunorm IV and Hirunorm V) by Cappiello, Mario, Vilardo, Pier Giuseppe, Lippi, Annalisa, Criscuoli, Marco, Corso, Antonella Del, Mura, Umberto

“…A study on the kinetics of human thrombin inhibition by two novel synthetic peptides (Hirunorm IV and Hirunorm V) and a comparison with recombinant hirudin and…”
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Interconversion pathways of aldose reductase induced by thiol compounds by Del Corso, A, Vilardo, P G, Barsotti, C, Cappiello, M, Cecconi, I, Dal Monte, M, Marini, I, Banditelli, S, Mura, U

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Site-Specific Inactivation of Aldose Reductase by 4-Hydroxynonenal by Corso, Antonella Del, Monte, Massimo Dal, Vilardo, Pier Giuseppe, Cecconi, Ilaria, Moschini, Roberta, Banditelli, Stefania, Cappiello, Mario, Tsai, Lin, Mura, Umberto

“…Bovine lens aldose reductase (ALR2), which catalyzes the NADPH-dependent reduction of 4-hydroxy-2-nonenal (HNE), is readily inactivated by its own substrate in…”
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Specifically Targeted Modification of Human Aldose Reductase by Physiological Disulfides by Cappiello, Mario, Voltarelli, Margaret, Cecconi, Ilaria, Vilardo, Pier Giuseppe, Dal Monte, Massimo, Marini, Isabella, Del Corso, Antonella, Wilson, David K., Quiocho, Florante A., Petrash, J. Mark, Mura, Umberto

“…Aldose reductase is inactivated by physiological disulfides such as GSSG and cystine. To study the mechanism of disulfide-induced enzyme inactivation, we…”
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Thioltransferase activity of bovine lens glutathione S-transferase by Dal Monte, M, Cecconi, I, Buono, F, Vilardo, P G, Del Corso, A, Mura, U

“…A Mu-class glutathione S-transferase purified to electrophoretic homogeneity from bovine lens displayed thioltransferase activity, catalysing the…”
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Modulation of aldose reductase activity through S-thiolation by physiological thiols by Cappiello, Mario, Amodeo, Pietro, Mendez, Blanca Lopez, Scaloni, Andrea, Vilardo, Pier Giuseppe, Cecconi, Ilaria, Monte, Massimo Dal, Banditelli, Stefania, Talamo, Fabio, Micheli, Vanna, Giblin, Frank J., Corso, Antonella Del, Mura, Umberto

“…The glutathionyl-modified aldose reductase (GS-ALR2) is unique, among different S-thiolated enzyme forms, in that it displays a lower specific activity than…”
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Hirunorms, Novel Hirudin-like Direct Thrombin Inhibitors by Cappiello, Mario, Vilardo, Pier Giuseppe, Del Corso, Antonella, Mura, Umberto

“…1. Hirunorms are new synthetic peptides designed to interact with thrombin in a similar way to the natural inhibitor hirudin. 2. Hirunorms are specific and…”
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Oxidative Modification of Aldose Reductase Induced by Copper Ion. Factors and Conditions Affecting the Process by Cecconi, Ilaria, Moroni, Maria, Vilardo, Pier Giuseppe, Dal Monte, Massimo, Borella, Paola, Rastelli, Giulio, Costantino, Luca, Garland, Donita, Carper, Deborah, Petrash, J. Mark, Del Corso, Antonella, Mura, Umberto

“…Bovine lens aldose reductase (ALR2) is inactivated by copper ion [Cu(II)] through an oxygen-independent oxidative modification process. A stoichiometry of 2…”
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Occurrence of Glutathione-Modified Aldose Reductase in Oxidatively Stressed Bovine Lens by Cappiello, M., Vilardo, P.G., Cecconi, I., Leverenz, V., Giblin, F.J., Delcorso, A., Mura, U.

“…The optimization of an affinity chromatography method on Matrex Orange resin allowed the separation of glutathione modified and native aldose reductase in…”
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Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL by Suzuki, Yoichi, Lanner, Carita, Kim, Jong-Hwa, Vilardo, Pier Giuseppe, Zhang, Hong, Yang, Jie, Cooper, Lori D., Steele, Marcella, Kennedy, Andrew, Bock, Cheryl B., Scrimgeour, Angus, Lawrence, John C., DePaoli-Roach, Anna A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/R GL by Suzuki, Yoichi, Lanner, Carita, Kim, Jong-Hwa, Vilardo, Pier Giuseppe, Zhang, Hong, Yang, Jie, Cooper, Lori D., Steele, Marcella, Kennedy, Andrew, Bock, Cheryl B., Scrimgeour, Angus, Lawrence, John C., DePaoli-Roach, Anna A.

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Oxidative modification of aldose reductase induced by copper ion. Definition of the metal-protein interaction mechanism by Cecconi, Ilaria, Scaloni, Andrea, Rastelli, Giulio, Moroni, Maria, Vilardo, Pier Giuseppe, Costantino, Luca, Cappiello, Mario, Garland, Donita, Carper, Deborah, Petrash, J Mark, Del Corso, Antonella, Mura, Umberto

“…Aldose reductase (ALR2) is susceptible to oxidative inactivation by copper ion. The mechanism underlying the reversible modification of ALR2 was studied by…”
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The Muscle-specific Protein Phosphatase PP1G/R sub(GL)(G sub(M)) Is Essential for Activation of Glycogen Synthase by Exercise by Aschenbach, W G, Suzuki, Y, Breeden, K, Prats, C, Hirshman, M F, Dufresne, S D, Sakamoto, K, Vilardo, P G, Steele, M, Kim, J, Jing, S, Goodyear, L J, DePaoli-Roach, A A

“…In skeletal muscle both insulin and contractile activity are physiological stimuli for glycogen synthesis, which is thought to result in part from the…”
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The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise by Aschenbach, W G, Suzuki, Y, Breeden, K, Prats, C, Hirshman, M F, Dufresne, S D, Sakamoto, K, Vilardo, P G, Steele, M, Kim, J H, Jing, S L, Goodyear, L J, DePaoli-Roach, A A

“…In skeletal muscle both insulin and contractile activity are physiological stimuli for glycogen synthesis, which is thought to result in part from the…”
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Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/R sub(GL) by Suzuki, Y, Lanner, C, Kim, J, Vilardo, P G, Zhang, H, Yang, J, Cooper, L D, Steele, M, Kennedy, A, Bock, C B, Scrimgeour, A, Lawrence, JCJr, Roach, AAD

“…The regulatory-targeting subunit (R sub(GL), also called G sub(M)) of the muscle-specific glycogen-associated protein phosphatase PP1G targets the enzyme to…”
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Physiological Thiols as Promoters of Glutathione Oxidation and Modifying Agents in Protein S-Thiolation by Del Corso, Antonella, Giuseppe Vilardo, Pier, Cappiello, Mario, Cecconi, Ilaria, Dal Monte, Massimo, Barsacchi, Daniela, Mura, Umberto

“…Glutathione is one of the most relevant antioxidants present in cells. It exerts its scavenging action through the involvement of efficient and ubiquitous…”
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