Search Results - "Vilaine, Jean‐Paul"
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New Biologically Active Hydrogen Sulfide Donors
Published in Chembiochem : a European journal of chemical biology (25-11-2013)“…Generous donors: The dithioperoxyanhydrides (CH3COS)2, (PhCOS)2, CH3COSSCO2Me and PhCOSSCO2Me act as thiol‐activated hydrogen sulfide donors in aqueous buffer…”
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2
Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice
Published in Journal of the American Heart Association (10-04-2014)“…Background Lipocalin‐2 is a proinflammatory adipokine upregulated in obese humans and animals. A pathogenic role of lipocalin‐2 in hypertension has been…”
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3
Innovation in coronary artery disease and heart failure: clinical benefits of pure heart rate reduction with ivabradine
Published in Annals of the New York Academy of Sciences (01-03-2011)“…The link between elevated heart rate and cardiovascular events is established in healthy individuals and in patients with cardiovascular disease. The new…”
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4
New Insights in the Contribution of Voltage-Gated Nav Channels to Rat Aorta Contraction
Published in PloS one (07-10-2009)“…Background Despite increasing evidence for the presence of voltage-gated Na+ channels (Nav) isoforms and measurements of Nav channel currents with the…”
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Anti-Ischemic Effects of Ivabradine, a Selective Heart Rate-Reducing Agent, in Exercise-Induced Myocardial Ischemia in Pigs
Published in Journal of cardiovascular pharmacology (01-11-2003)“…The effects of ivabradine, a novel heart rate-reducing agent that inhibits the cardiac pacemaker current If, were compared with those of the β-adrenergic…”
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6
Potassium ions and endothelium‐derived hyperpolarizing factor in guinea‐pig carotid and porcine coronary arteries
Published in British journal of pharmacology (01-05-1999)“…Experiments were designed to determine in two arteries (the guinea‐pig carotid and the porcine coronary arteries) whether or not the endothelium‐derived…”
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7
SBP, DBP, and pulse blood pressure variability are temporally associated with the increase in pulse wave velocity in a model of aortic stiffness
Published in Journal of hypertension (01-04-2016)“…BACKGROUND:Enhanced aortic stiffness and blood pressure variability (BPV) are independent risk factors for cardiovascular disease and all-cause mortality in…”
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8
Status of the Endothelium-derived Hyperpolarizing Factor Pathway in Coronary Arteries After Heterotopic Heart Transplantation
Published in The Journal of heart and lung transplantation (2007)“…Background After the first year of transplantation, the major limitation to long-term survival is the development of graft coronary vasculopathy, characterized…”
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Chronic mild hyperhomocysteinemia induces aortic endothelial dysfunction but does not elevate arterial pressure in rats
Published in Journal of vascular research (01-03-2005)“…Mild hyperhomocysteinemia is prevalent in the general population and has been linked to endothelial dysfunction and high arterial pressure (AP) in clinical…”
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10
Comparison of coronary endothelial dysfunction in the working and nonworking graft in porcine heterotopic heart transplantation
Published in Transplantation (27-09-2002)“…The nonworking heterotopic heart transplantation model has been used extensively for the study of rejection and coronary endothelial function in different…”
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11
Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen—A novel biomarker of atherosclerotic plaque remodeling
Published in Clinical biochemistry (01-07-2011)“…Degradation of collagen in the arterial wall by matrix metalloproteinases is the hallmark of atherosclerosis. We have developed an ELISA for the quantification…”
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12
Persistence of the nitric oxide pathway in the aorta of hypercholesterolemic apolipoprotein-E-deficient mice
Published in Journal of vascular research (01-03-2003)“…The markers of the bioavailability of NO (endothelium-dependent relaxation to acetylcholine and cyclic GMP content) in the thoracic aorta of…”
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13
Cardiac FKBP12.6 overexpression protects against triggered ventricular tachycardia in pressure overloaded mouse hearts
Published in Basic research in cardiology (01-03-2012)“…Alterations in RyR2 function have been proposed as a major pathophysiological mechanism of arrhythmias and heart failure (HF). Cardiac FKBP12.6 overexpression…”
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14
Cells derived from regenerated endothelium of the porcine coronary artery contain more oxidized forms of apolipoprotein-B-100 without a modification in the uptake of oxidized LDL
Published in Journal of vascular research (01-07-2003)“…Increased accumulation of lipoproteins and cholesterol within cells from regenerated endothelium may be responsible for their reported dysfunction. This study…”
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15
Morphological heterogeneity with normal expression but altered function of G proteins in porcine cultured regenerated coronary endothelial cells
Published in British journal of pharmacology (01-11-1997)“…1 Experiments were designed to investigate whether the pertussis toxin‐dependent endothelial dysfunction following balloon injury is due to a reduced…”
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Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells
Published in Cardiovascular research (01-04-2009)“…Aims The requirement of endothelial NO synthase (NOS3) calcium to produce NO is well described, although the effect of NO on intracellular calcium levels…”
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17
Role of the Renin-Angiotensin System in Neointima Formation After Injury in Rabbits
Published in Hypertension (Dallas, Tex. 1979) (01-12-1994)“…We investigated the role of the renin-angiotensin system in neointima formation in a species in which converting enzyme inhibitors have been so far ineffective…”
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Thromboxane A2/Prostaglandin H2 Receptor Activation Mediates Angiotensin II–Induced Postischemic Neovascularization
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2006)“…OBJECTIVE—We analyzed the involvement of thromboxane (TX) A2/prostaglandin (PG) H2 (TP) receptor in ischemia-induced neovascularization in mice. METHODS AND…”
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Role of Angiotensin Subtype 2 Receptor in Neointima Formation After Vascular Injury
Published in Hypertension (Dallas, Tex. 1979) (01-12-1992)“…The role of angiotensin receptor subtypes 1 and 2 was assessed on neointima formation after injury in rat carotid artery. The effects of angiotensin converting…”
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Phenotypic and Functional Changes in Regenerated Porcine Coronary Endothelial Cells: Increased Uptake of Modified LDL and Reduced Production of NO
Published in Circulation research (28-04-2000)“…Porcine coronary arteries with regenerated endothelium exhibit impaired endothelium-dependent relaxations. Experiments were designed to analyze the structural…”
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