Search Results - "Vilaine, JP"

KEY ROLE OF TRPC3 CHANNELS IN CALCIUM HOMEOSTASIS ALTERATION RELATED TO NO DEFICIENCY IN AGED PORCINE ENDOTHELIAL CELLS by Banquet, S, Bourguignon, MP, Garry, A, Royere, E, Gosgnach, W, Thollon, C, Villeneuve, N, Vilaine, JP

“…Abstract only NO controls the activity of canonical transient receptor potential channel (TRPC) in endothelial cells. Our group already provided evidences that…”
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A new somatostatin analog with optimized ring size inhibits neointima formation induced by balloon injury in rats without altering growth hormone release by Thurieau, C, Janiak, P, Krantic, S, Guyard, C, Pillon, A, N, Kucharczyk, Vilaine, JP, Fauchère, JL

“…We report on the synthesis and pharmacological properties of a new series of somatostatin analogs. Two lower homologs of lysine, 2,3-diaminopropanoic acid and…”
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REDUCED NO BIOAVAILABILITY, OXIDATIVE STRESS AND ALTERATION OF CALCIUM HOMEOSTASIS IN VASCULAR ENDOTHELIUM FROM DIABETIC MICE by Banquet, S, Bourguignon, MP, Garry, A, Royere, E, Crespo, C, Lapret, I, Simonet, S, Gosgnach, W, Thollon, C, Villeneuve, N, Vilaine, JP

“…Abstract only Endothelial dysfunction is a major risk factor for vascular complications associated with diabetes. The purpose of this study was to evaluate the…”
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Anti-Ischemic Effects of Ivabradine, a Selective Heart Rate-Reducing Agent, in Exercise-Induced Myocardial Ischemia in Pigs by Vilaine, Jean-Paul, Bidouard, Jean-Pierre, Lesage, Ludovic, Reure, Hélène, Péglion, Jean-Louis

“…The effects of ivabradine, a novel heart rate-reducing agent that inhibits the cardiac pacemaker current If, were compared with those of the β-adrenergic…”
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Role of gap junctions and EETs in endothelium‐dependent hyperpolarization of porcine coronary artery by Edwards, G, Thollon, C, Gardener, M J, Félétou, M, Vilaine, J ‐P, Vanhoutte, P M, Weston, A H

“…The effects of endothelium‐derived hyperpolarizing factor (EDHF: elicited using substance P or bradykinin) were compared with those of 11,12‐EET in pig…”
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The discovery of the selective If current inhibitor ivabradine (Procoralan): a new therapeutic approach to ischemic heart disease by Vilaine, Jean-Paul

“…Coronary artery disease is still a major cause of morbidity and mortality in the industrialized countries and its prevalence is predicted to grow with the…”
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Thromboxane A2/Prostaglandin H2 Receptor Activation Mediates Angiotensin II–Induced Postischemic Neovascularization by Michel, Frédéric, Silvestre, Jean-Sébastien, Waeckel, Ludovic, Corda, Stefano, Verbeuren, Tony, Vilaine, Jean Paul, Clergue, Michel, Duriez, Micheline, Levy, Bernard I

“…OBJECTIVE—We analyzed the involvement of thromboxane (TX) A2/prostaglandin (PG) H2 (TP) receptor in ischemia-induced neovascularization in mice. METHODS AND…”
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Consequences of reduced production of NO on vascular reactivity of porcine coronary arteries after angioplasty: importance of EDHF by Thollon, Catherine, Fournet‐Bourguignon, Marie Pierre, Saboureau, Delphine, Lesage, Ludovic, Reure, Hélène, Vanhoutte, Paul M, Vilaine, Jean Paul

“…The consequences of the reduced production of nitric oxide (NO) by cells from regenerated endothelium were investigated by measuring membrane potential of…”
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Role of Angiotensin Subtype 2 Receptor in Neointima Formation After Vascular Injury by Janiak, Philip, Pillon, Aline, Prost, Jean-François, Vilaine, Jean-Paul

“…The role of angiotensin receptor subtypes 1 and 2 was assessed on neointima formation after injury in rat carotid artery. The effects of angiotensin converting…”
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Phenotypic and Functional Changes in Regenerated Porcine Coronary Endothelial Cells: Increased Uptake of Modified LDL and Reduced Production of NO by Fournet-Bourguignon, Marie-Pierre, Castedo-Delrieu, Maria, Bidouard, Jean-Pierre, Leonce, Stephane, Saboureau, Delphine, Delescluse, Isabelle, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…Porcine coronary arteries with regenerated endothelium exhibit impaired endothelium-dependent relaxations. Experiments were designed to analyze the structural…”
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Cannabinoid CB1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries by Chataigneau, T, Félétou, M, Thollon, C, Villeneuve, N, Vilaine, J‐ P., Duhault, J, Vanhoutte, P M.

“…1 The purpose of these experiments was to determine whether or not the endothelium‐dependent hyperpolarizations of the vascular smooth muscle cells (observed…”
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Stereospecific in vitro and in vivo effects of the new sinus node inhibitor (+)-S 16257 by Thollon, Catherine, Bidouard, Jean-Pierre, Cambarrat, Christine, Lesage, Ludovic, Reure, Hélène, Delescluse, Isabelle, Vian, Joël, Peglion, Jean-Louis, Vilaine, Jean-Paul

“…The effects of the two isomers, (+)-S 16257 and (−)-S 16260, of a new bradycardic agent, (±)-S 15544 (7,8-dimethoxy 3-{3-{[(4,5-dimethoxybenzocyclobutan-1-yl)…”
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Role of force ? frequency relation during AV?block, sinus node block and betaadrenoceptor block in conscious animals by Pauw, M., Vilaine, J.?P., Heyndrickx, G.R.

“…Myocardial contractility is regulated by adrenergic stimulation, the strength-length relationship and the force-frequency relationship or Bowditch effect. The…”
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Inhibiting the NO pathway with intracoronary L-NAME infusion increases endothelial dysfunction and intimal hyperplasia after heart transplantation by Perrault, Louis P, Malo, Olivier, Bidouard, Jean-Pierre, Villeneuve, Nicole, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…The endothelium protects the vascular wall through the nitric oxide (NO) release. Coronary endothelial dysfunction occurs early after heart transplantation and…”
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Hypercholesterolemia Increases Coronary Endothelial Dysfunction, Lipid Content, and Accelerated Atherosclerosis After Heart Transplantation by Perrault, Louis P, Mahlberg, Florence, Breugnot, Christine, Bidouard, Jean-Pierre, Villeneuve, Nicole, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…ABSTRACTHyperlipidemia may increase endothelial damage and promote accelerated atherogenesis in graft coronary vasculopathy. To study the effects of…”
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Alteration of Endothelium-Dependent Hyperpolarizations in Porcine Coronary Arteries With Regenerated Endothelium by Thollon, Catherine, Bidouard, Jean P, Cambarrat, Christine, Delescluse, Isabelle, Villeneuve, Nicole, Vanhoutte, Paul M, Vilaine, Jean P

“…The present study was designed to test the ability of regenerated endothelium to evoke endothelium-dependent hyperpolarizations. Hyperpolarizations induced by…”
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Angiotensin I-Converting Enzyme Genotype Influences Arterial Response to Injury in Normotensive Rats by Challah, Mireille, Villard, Eric, Philippe, Monique, Ribadeau-Dumas, Antoine, Giraudeau, Bruno, Janiak, Philip, Vilaine, Jean-Paul, Soubrier, Florent, Michel, Jean-Baptiste

“…Two normotensive strains of rat, the Lou and Brown Norway (BN) strains, have contrasting levels of plasma angiotensin-converting enzyme (ACE). To investigate…”
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Chronic mild hyperhomocysteinemia induces aortic endothelial dysfunction but does not elevate arterial pressure in rats by Miao, Chao-Yu, Villeneuve, Nicole, Brunel-Jacquemin, Christine, Petit, Christine, Guillaumin, Jean-Philippe, Gransagne, Denis, Briant, Cyril, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…Mild hyperhomocysteinemia is prevalent in the general population and has been linked to endothelial dysfunction and high arterial pressure (AP) in clinical…”
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Comparison of coronary endothelial dysfunction in the working and nonworking graft in porcine heterotopic heart transplantation by PERRAULT, Louis P, BIDOUARD, Jean-Pierre, DESJARDINS, Nathalie, VILLENEUVE, Nicole, VILAINE, Jean-Paul, VANHOUTTE, Paul M

“…The nonworking heterotopic heart transplantation model has been used extensively for the study of rejection and coronary endothelial function in different…”
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Persistence of the nitric oxide pathway in the aorta of hypercholesterolemic apolipoprotein-E-deficient mice by Villeneuve, Nicole, Fortuno, Ana, Sauvage, Marie, Fournier, Nancy, Breugnot, Christine, Jacquemin, Christine, Petit, Christine, Gosgnach, Willy, Carpentier, Nathalie, Vanhoutte, Paul, Vilaine, Jean-Paul

“…The markers of the bioavailability of NO (endothelium-dependent relaxation to acetylcholine and cyclic GMP content) in the thoracic aorta of…”
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