Search Results - "Vilaine, J‐ P."

Use‐dependent inhibition of hHCN4 by ivabradine and relationship with reduction in pacemaker activity by Thollon, C, Bedut, S, Villeneuve, N, Cogé, F, Piffard, L, Guillaumin, J‐P, Brunel‐Jacquemin, C, Chomarat, P, Boutin, J‐A, Peglion, J‐L, Vilaine, J‐P

“…Background and purpose: Ivabradine, a specific and use‐dependent I f inhibitor, exerts anti‐ischaemic activity purely by reducing heart rate. The aim of this…”
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Role of gap junctions and EETs in endothelium‐dependent hyperpolarization of porcine coronary artery by Edwards, G, Thollon, C, Gardener, M J, Félétou, M, Vilaine, J ‐P, Vanhoutte, P M, Weston, A H

“…The effects of endothelium‐derived hyperpolarizing factor (EDHF: elicited using substance P or bradykinin) were compared with those of 11,12‐EET in pig…”
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Cannabinoid CB1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries by Chataigneau, T, Félétou, M, Thollon, C, Villeneuve, N, Vilaine, J‐ P., Duhault, J, Vanhoutte, P M.

“…1 The purpose of these experiments was to determine whether or not the endothelium‐dependent hyperpolarizations of the vascular smooth muscle cells (observed…”
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P8.12 Arterial Distension-Pressure Loop Analysis in Hypertensive Rats: Advantages, Pitfalls and Possibilities by Vayssettes-Courchay, C., Ragonnet, C., Lindesay, G., Chimenti, S., Isabelle, M., Vilaine, J.-P.

“…Arterial wall viscosity (AWV) of central arteries, as well as distensibility, is important to properly buffer systolic ejection pressure. AWV is measured…”
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Electrophysiological effects of S 16257, a novel sino‐atrial node modulator, on rabbit and guinea‐pig cardiac preparations: comparison with UL‐FS 49 by Thollon, Catherine, Cambarrat, Christine, Vian, Joël, Prost, Jean‐François, Peglion, Jean Louis, Vilaine, Jean Paul

“…1 S 16257 is a new bradycardic agent. Its electropharmacological profile has been compared to that of the known bradycardic compound UL‐FS 49 (Zatebradine)…”
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3.2: Local Arterial Stiffness Assessed by Echo Tracking is Not Associated with an Increased Pulse Wave Velocity in Hypercholesterolemic Rabbit by Isabelle, M., Ragonnet, C., Chimenti, S., Badier-Commander, C., Vayssettes-Courchay, C., Villeneuve, N., Vilaine, J.-P.

“…Arterial stiffness (AS) is generally measured by regional arterial pulse wave velocity (rPWV) or locally by arterial distensibility. Although often used…”
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Role of Angiotensin Subtype 2 Receptor in Neointima Formation After Vascular Injury by Janiak, Philip, Pillon, Aline, Prost, Jean-François, Vilaine, Jean-Paul

“…The role of angiotensin receptor subtypes 1 and 2 was assessed on neointima formation after injury in rat carotid artery. The effects of angiotensin converting…”
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Phenotypic and Functional Changes in Regenerated Porcine Coronary Endothelial Cells: Increased Uptake of Modified LDL and Reduced Production of NO by Fournet-Bourguignon, Marie-Pierre, Castedo-Delrieu, Maria, Bidouard, Jean-Pierre, Leonce, Stephane, Saboureau, Delphine, Delescluse, Isabelle, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…Porcine coronary arteries with regenerated endothelium exhibit impaired endothelium-dependent relaxations. Experiments were designed to analyze the structural…”
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Stereospecific in vitro and in vivo effects of the new sinus node inhibitor (+)-S 16257 by Thollon, Catherine, Bidouard, Jean-Pierre, Cambarrat, Christine, Lesage, Ludovic, Reure, Hélène, Delescluse, Isabelle, Vian, Joël, Peglion, Jean-Louis, Vilaine, Jean-Paul

“…The effects of the two isomers, (+)-S 16257 and (−)-S 16260, of a new bradycardic agent, (±)-S 15544 (7,8-dimethoxy 3-{3-{[(4,5-dimethoxybenzocyclobutan-1-yl)…”
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Role of force ? frequency relation during AV?block, sinus node block and betaadrenoceptor block in conscious animals by Pauw, M., Vilaine, J.?P., Heyndrickx, G.R.

“…Myocardial contractility is regulated by adrenergic stimulation, the strength-length relationship and the force-frequency relationship or Bowditch effect. The…”
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Hypercholesterolemia Increases Coronary Endothelial Dysfunction, Lipid Content, and Accelerated Atherosclerosis After Heart Transplantation by Perrault, Louis P, Mahlberg, Florence, Breugnot, Christine, Bidouard, Jean-Pierre, Villeneuve, Nicole, Vilaine, Jean-Paul, Vanhoutte, Paul M

“…ABSTRACTHyperlipidemia may increase endothelial damage and promote accelerated atherogenesis in graft coronary vasculopathy. To study the effects of…”
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Time course of coronary endothelial dysfunction in acute untreated rejection after heterotopic heart transplantation by Perrault, L P, Bidouard, J P, Janiak, P, Villeneuve, N, Bruneval, P, Vilaine, J P, Vanhoutte, P M

“…Endothelial dysfunction is one of the early events leading to atherosclerosis. It occurs early after orthotopic heart transplantation and precedes the…”
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Alteration of Endothelium-Dependent Hyperpolarizations in Porcine Coronary Arteries With Regenerated Endothelium by Thollon, Catherine, Bidouard, Jean P, Cambarrat, Christine, Delescluse, Isabelle, Villeneuve, Nicole, Vanhoutte, Paul M, Vilaine, Jean P

“…The present study was designed to test the ability of regenerated endothelium to evoke endothelium-dependent hyperpolarizations. Hyperpolarizations induced by…”
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Angiotensin I-Converting Enzyme Genotype Influences Arterial Response to Injury in Normotensive Rats by Challah, Mireille, Villard, Eric, Philippe, Monique, Ribadeau-Dumas, Antoine, Giraudeau, Bruno, Janiak, Philip, Vilaine, Jean-Paul, Soubrier, Florent, Michel, Jean-Baptiste

“…Two normotensive strains of rat, the Lou and Brown Norway (BN) strains, have contrasting levels of plasma angiotensin-converting enzyme (ACE). To investigate…”
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Role of the Renin-Angiotensin System in Neointima Formation After Injury in Rabbits by Janiak, Philip, Librt, Olivier, Vilaine, Jean-Paul

“…We investigated the role of the renin-angiotensin system in neointima formation in a species in which converting enzyme inhibitors have been so far ineffective…”
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Arterial distension-pressure loop analysis in hypertensive rats: Advantages, pitfalls and possibilities by Vayssettes-Courchay, C, Ragonnet, C, Lindesay, G, Chimenti, S, Isabelle, M, Vilaine, J.-P

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Impairment of G-protein-mediated signal transduction in the porcine coronary endothelium during rejection after heart transplantation by PERRAULT, L. P, BIDOUARD, J.-P, JANIAK, P, VILLENEUVE, N, BRUNEVAL, P, VILAINE, J.-P, VANHOUTTE, P. M

“…Endothelial dysfunction is an early event leading to atherosclerosis. It also occurs after orthotopic heart transplantation and can be used to predict the…”
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3.3 Pressure-Independent Aortic Stiffening Evaluation in Various Hypertensive Rat Models in Vivo, Via Pulsatile Diameter Recording by Vayssettes-Courchay, C., Ragonnet, C., Isabelle, M., Vilaine, J. P.

“…We have shown that in addition to compliance and distensibility, the analysis of the arterial distension (pulsatile diameter) via echotracking (ArtLab)…”
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Morphological heterogeneity with normal expression but altered function of G proteins in porcine cultured regenerated coronary endothelial cells by Borg‐Capra, Catherine, Fournet‐Bourguignon, Marie‐Pierre, Janiak, Philip, Villeneuve, Nicole, Bidouard, Jean‐Pierre, Vilaine, Jean‐Paul, Vanhoutte, Paul M.

“…1 Experiments were designed to investigate whether the pertussis toxin‐dependent endothelial dysfunction following balloon injury is due to a reduced…”
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Electrochemical detection of nitric oxide production in perfused pig coronary artery: comparison of the performances of two electrochemical sensors by Villeneuve, N., Bedioui, F., Voituriez, K., Avaro, S., Vilaine, J.P.

“…In situ direct measurement of nitric oxide (NO) in biological media is now possible by means of electrochemical detection. In the literature, there are…”
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