Search Results - "Vila, Olaia F."

Quantification of human neuromuscular function through optogenetics by Vila, Olaia F, Uzel, Sebastien G M, Ma, Stephen P, Williams, Damian, Pak, Joseph, Kamm, Roger D, Vunjak-Novakovic, Gordana

“…The study of human neuromuscular diseases has traditionally been performed in animal models, due to the difficulty of performing studies in human subjects…”
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Titin-truncating variants in hiPSC cardiomyocytes induce pathogenic proteinopathy and sarcomere defects with preserved core contractile machinery by Huang, Guanyi, Bisaria, Anjali, Wakefield, Devin L., Yamawaki, Tracy M., Luo, Xin, Zhang, Jingli A., Vigneault, Patrick, Wang, Jinghong, Reagan, Jeffrey D., Oliverio, Oliver, Zhou, Hong, Li, Chi-Ming, Vila, Olaia F., Wang, Songli, Malik, Fady I., Hartman, James J., Hale, Christopher M.

“…Titin-truncating variants (TTNtv) are the single largest genetic cause of dilated cardiomyopathy (DCM). In this study we modeled disease phenotypes of A-band…”
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Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response by Alieva, Maria, Bagó, Juli R, Aguilar, Elisabet, Soler-Botija, Carolina, Vila, Olaia F, Molet, Joan, Gambhir, Sanjiv S, Rubio, Nuria, Blanco, Jerónimo

“…Genetically modified adipose tissue derived mesenchymal stromal cells (hAMSCs) with tumor homing capacity have been proposed for localized therapy of chemo-…”
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Glioblastoma Bystander Cell Therapy: Improvements in Treatment and Insights into the Therapy Mechanisms by Guerra-Rebollo, Marta, Nogueira de Moraes, Carolina, Alcoholado, Cristina, Soler-Botija, Carolina, Sanchez-Cid, Lourdes, Vila, Olaia F., Meca-Cortés, Oscar, Ramos-Romero, Sara, Rubio, Nuria, Becerra, José, Blanco, Jeronimo, Garrido, Cristina

“…A preclinical model of glioblastoma (GB) bystander cell therapy using human adipose mesenchymal stromal cells (hAMSCs) is used to address the issues of cell…”
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In vitro models of neuromuscular junctions and their potential for novel drug discovery and development by Vila, Olaia F, Qu, Yihuai, Vunjak-Novakovic, Gordana

“…: Neuromuscular Junctions (NMJs) are the synapses between motor neurons and skeletal muscle fibers, and they are responsible for voluntary motor function. NMJs…”
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Bioengineered optogenetic model of human neuromuscular junction by Vila, Olaia F., Chavez, Miguel, Ma, Stephen P., Yeager, Keith, Zholudeva, Lyandysha V., Colón-Mercado, Jennifer M., Qu, Yihuai, Nash, Trevor R., Lai, Carmen, Feliciano, Carissa M., Carter, Matthew, Kamm, Roger D., Judge, Luke M., Conklin, Bruce R., Ward, Michael E., McDevitt, Todd C., Vunjak-Novakovic, Gordana

“…Functional human tissues engineered from patient-specific induced pluripotent stem cells (hiPSCs) hold great promise for investigating the progression,…”
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Engineering and Characterization of an Optogenetic Model of the Human Neuromuscular Junction by Liberman, Martin, Chavez, Miguel, Nash, Trevor R, Vila, Olaia F, Vunjak-Novakovic, Gordana

“…Many neuromuscular diseases, such as myasthenia gravis (MG), are associated with dysfunction of the neuromuscular junction (NMJ), which is difficult to…”
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Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors by Vila, Olaia F., Martino, Mikaël M., Nebuloni, Laura, Kuhn, Gisela, Pérez-Amodio, Soledad, Müller, Ralph, Hubbell, Jeffrey A., Rubio, Nuria, Blanco, Jerónimo

“…[Display omitted] In this work we have evaluated the capacity of bone morphogenetic protein-2 (BMP-2) and fibrin-binding platelet-derived growth factor-BB…”
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Calcium phosphate glass improves angiogenesis capacity of poly(lactic acid) scaffolds and stimulates differentiation of adipose tissue-derived mesenchymal stromal cells to the endothelial lineage by Vila, Olaia F., Bagó, Juli R., Navarro, Melba, Alieva, Maria, Aguilar, Elisabeth, Engel, Elisabeth, Planell, Josep, Rubio, Nuria, Blanco, Jerónimo

“…The angiogenic capacity of a new biomaterial composite of poly(lactic acid) and calcium phosphate glass (PLA/CaP) was analyzed by noninvasive bioluminescence…”
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Fast-proliferating adipose tissue mesenchymal-stromal-like cells for therapy by Aguilar, Elisabet, Bagó, Julio Rodriguez, Soler-Botija, Carol, Alieva, Maria, Rigola, Maria Angeles, Fuster, Carme, Vila, Olaia F, Rubio, Nuria, Blanco, Jeronimo

“…Human mesenchymal stromal cells, whether from the bone marrow or adipose tissue (hASCs), are promising cell therapy agents. However, generation of abundant…”
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In vivo bioluminescence imaging of cell differentiation in biomaterials: a platform for scaffold development by Bagó, Juli R, Aguilar, Elisabeth, Alieva, Maria, Soler-Botija, Carolina, Vila, Olaia F, Claros, Silvia, Andrades, José A, Becerra, José, Rubio, Nuria, Blanco, Jerónimo

“…In vivo testing is a mandatory last step in scaffold development. Agile longitudinal noninvasive real-time monitoring of stem cell behavior in biomaterials…”
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Real-Time Bioluminescence Imaging of Cell Distribution, Growth, and Differentiation in a Three-Dimensional Scaffold Under Interstitial Perfusion for Tissue Engineering by Vila, Olaia F, Garrido, Cristina, Cano, Irene, Guerra-Rebollo, Marta, Navarro, Melba, Meca-Cortés, Oscar, Ma, Stephen P, Engel, Elisabeth, Rubio, Nuria, Blanco, Jerónimo

“…Bioreactor systems allow safe and reproducible production of tissue constructs and functional analysis of cell behavior in biomaterials. However, current…”
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