Search Results - "Vijver, M."

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets by Turner, N, Lambros, M B, Horlings, H M, Pearson, A, Sharpe, R, Natrajan, R, Geyer, F C, van Kouwenhove, M, Kreike, B, Mackay, A, Ashworth, A, van de Vijver, M J, Reis-Filho, J S

“…Triple negative breast cancers (TNBCs) have a relatively poor prognosis and cannot be effectively treated with current targeted therapies. We searched for…”
Get full text

Refinement of breast cancer classification by molecular characterization of histological special types by Weigelt, B, Horlings, HM, Kreike, B, Hayes, MM, Hauptmann, M, Wessels, LFA, de Jong, D, Van de Vijver, MJ, Veer, LJ Van't, Peterse, JL

“…Most invasive breast cancers are classified as invasive ductal carcinoma not otherwise specified (IDC NOS), whereas about 25% are defined as histological…”
Get full text

A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study by Drukker, C.A., Bueno‐de‐Mesquita, J.M., Retèl, V.P., Harten, W.H., Tinteren, H., Wesseling, J., Roumen, R.M.H., Knauer, M., Veer, L.J., Sonke, G.S., Rutgers, E.J.T., Vijver, M.J., Linn, S.C.

“…The 70‐gene signature (MammaPrint™) has been developed on retrospective series of breast cancer patients to predict the risk of breast cancer distant…”
Get full text

Exploring uptake and biodistribution of polystyrene (nano)particles in zebrafish embryos at different developmental stages by van Pomeren, M., Brun, N.R., Peijnenburg, W.J.G.M., Vijver, M.G.

“…•Only uptake (across epidermis) observed for particles smaller than 50nm.•Small particles were detected to have biodistribution and even ended up in the…”
Get full text

A specific gene expression signature for visceral organ metastasis in breast cancer by Savci-Heijink, C D, Halfwerk, H, Koster, J, Horlings, H M, van de Vijver, M J

“…Visceral organ metastasis is associated with poor survival outcomes in terms of metastasis free- and overall survival in breast carcinomas. Identification of a…”
Get full text

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer by Liu, G, Bollig-Fischer, A, Kreike, B, van de Vijver, M J, Abrams, J, Ethier, S P, Yang, Z -Q

“…Earlier, mapping of the 9p23–24 amplicon in esophageal cancer cell lines led us to the positional cloning of gene amplified in squamous cell carcinoma 1 (…”
Get full text

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior by Savci-Heijink, C. D., Halfwerk, H., Hooijer, G. K. J., Koster, J., Horlings, H. M., Meijer, S. L., van de Vijver, M. J.

“…Background Epithelial-to-mesenchymal transition (EMT) has been implicated as an important step in the development of distant metastases. We therefore wished to…”
Get full text

Defueling the impasse: EU political discourse on e-fuels by Birel, T., Breeman, G.E., van Buitenen, A., Vijver, M.G.

“…As part of its ‘Fit for 55’ package, the European Commission proposed to ban internal combustion engines in new cars and vans from 2035 onwards. Although…”
Get full text

Assessment of a HER2 scoring system for gastric cancer: results from a validation study by Hofmann, M, Stoss, O, Shi, D, Büttner, R, Van De Vijver, M, Kim, W, Ochiai, A, Rüschoff, J, Henkel, T

“…Aims:  Human epidermal growth factor receptor 2 (HER2) overexpression/amplification is implicated in the development of various solid tumour types. Validated…”
Get full text

Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement by Guiu, S., Michiels, S., André, F., Cortes, J., Denkert, C., Di Leo, A., Hennessy, B.T., Sorlie, T., Sotiriou, C., Turner, N., Van de Vijver, M., Viale, G., Loi, S., Reis-Filho, J.S.

“…The 2012 IMPAKT task force investigated the medical usefulness of current methods for the classification of breast cancer into the ‘intrinsic’ molecular…”
Get full text

A review of the ecological effects of radiofrequency electromagnetic fields (RF-EMF) by Cucurachi, S., Tamis, W.L.M., Vijver, M.G., Peijnenburg, W.J.G.M., Bolte, J.F.B., de Snoo, G.R.

“…This article presents a systematic review of published scientific studies on the potential ecological effects of radiofrequency electromagnetic fields (RF-EMF)…”
Get full text

Validation of 70-gene prognosis signature in node-negative breast cancer by Bueno-de-Mesquita, J. M, Linn, S. C, Keijzer, R, Wesseling, J, Nuyten, D. S. A, van Krimpen, C, Meijers, C, de Graaf, P. W, Bos, M. M. E. M, Hart, A. A. M, Rutgers, E. J. T, Peterse, J. L, Halfwerk, H, de Groot, R, Pronk, A, Floore, A. N, Glas, A. M, van't Veer, L. J, van de Vijver, M. J

“…Purpose The 70-gene prognosis signature (van't Veer et al., Nature 415(6871):530-536, 2002) may improve the selection of lymph node-negative breast cancer…”
Get full text

A prospective ecological risk assessment of high-efficiency III-V/silicon tandem solar cells by Blanco, C F, Quik, J T K, Hof, M, Fuortes, A, Behrens, P, Cucurachi, S, Peijnenburg, W J G M, Dimroth, F, Vijver, M G

“…III-V/Silicon tandem solar cells offer one of the most promising avenues for high-efficiency, high-stability photovoltaics. However, a key concern is the…”
Get more information

Five-Year Results of the Preoperative Accelerated Partial Breast Irradiation (PAPBI) Trial by Bosma, Sophie C.J., Leij, Femke, Vreeswijk, Sandra, Maaker, Michiel de, Wesseling, Jelle, Vijver, Marc van de, Scholten, Astrid, Rivera, Sofia, Bourgier, Celine, Auzac, Guillaume, Foukakis, Theodoros, Lekberg, Tobias, Bongard, Desiree, Loo, Claudette, Rutgers, Emiel, Bartelink, Harry, Elkhuizen, Paula H.M.

“…In this multicenter phase 2 feasibility study, we investigated the impact of preoperative accelerated partial breast irradiation (PAPBI) on local control,…”
Get full text

An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients by Vollebergh, M.A., Lips, E.H., Nederlof, P.M., Wessels, L.F.A., Schmidt, M.K., van Beers, E.H., Cornelissen, S., Holtkamp, M., Froklage, F.E., de Vries, E.G.E., Schrama, J.G., Wesseling, J., van de Vijver, M.J., van Tinteren, H., de Bruin, M., Hauptmann, M., Rodenhuis, S., Linn, S.C.

“…Breast cancer cells deficient for BRCA1 are hypersensitive to agents inducing DNA double-strand breaks (DSB), such as bifunctional alkylators and platinum…”
Get full text

The biodistribution and immuno-responses of differently shaped non-modified gold particles in zebrafish embryos by van Pomeren, M., Peijnenburg, W.J.G.M., Vlieg, R.C., van Noort, S.J.T., Vijver, M.G.

“…Important questions raised in (nano)ecotoxicology are whether biodistribution of nanoparticles (NPs) is affected by particle shape and to what extent local…”
Get full text

CT-Colonography vs. Colonoscopy for Detection of High-Risk Sessile Serrated Polyps by IJspeert, J E G, Tutein Nolthenius, C J, Kuipers, E J, van Leerdam, M E, Nio, C Y, Thomeer, M G J, Biermann, K, van de Vijver, M J, Dekker, E, Stoker, J

“…Sessile serrated polyps (SSPs) are suggested to be the precursors of 15-30% of all colorectal cancers (CRCs). Therefore, CRC screening modalities should also…”
Get full text

Very low local recurrence rates after breast-conserving therapy: analysis of 8485 patients treated over a 28-year period by Bosma, S. C. J., van der Leij, F., van Werkhoven, E., Bartelink, H., Wesseling, J., Linn, S., Rutgers, E. J., van de Vijver, M. J., Elkhuizen, P. H. M.

“…The purpose of this study was to study the impact of changes in clinical practice on outcome in patients treated with breast-conserving therapy (BCT) over a…”
Get full text

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas by Jordanova, E. S., Vijver, M. J. van de, Kenter, G. G., Dijk, F., Savci-Heijink, C. D., Buist, M. R., Rutten, M. J.

“…Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of…”
Get full text

Metallic nanomaterials: From (eco)toxicity to risk assessment by Peijnenburg, W., Vijver, M.

Get full text