Search Results - "Vijayasurian Easwaran"

Cross-regulation of β-catenin–LEF/TCF and retinoid signaling pathways by Easwaran, Vijayasurian, Pishvaian, Michael, Salimuddin, Byers, Stephen

“…Vitamin A derivatives (retinoids) are potent regulators of embryogenesis, cell proliferation, epithelial cell differentiation and carcinogenesis [1]. In breast…”
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The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck) by Sabat, Mark, VanRens, John C., Laufersweiler, Matthew J., Brugel, Todd A., Maier, Jennifer, Golebiowski, Adam, De, Biswanath, Easwaran, Vijayasurian, Hsieh, Lily C., Walter, Richard L., Mekel, Marlene J., Evdokimov, Artem, Janusz, Michael J.

“…This communication details the synthesis, biological activity, and binding mode of a novel class of 2-benzimidazole substituted pyrimidines. The most potent…”
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MALDI-TOF MS as a label-free approach to rapid inhibitor screening by GREIS, Kenneth D, SONGTAO ZHOU, BURT, Thomas M, CARR, Andrew N, DOLAN, Elizabeth, EASWARAN, Vijayasurian, EVDOKIMOV, Artem, KAWAMOTO, Richard, ROESGEN, Jeff, DAVIS, Gregory F

“…Mass Spectrometry (MS) has been widely reported for measuring the conversion of substrates to products for enzyme assays. These measurements are typically…”
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The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling by Easwaran, V, Song, V, Polakis, P, Byers, S

“…The tumor suppressor function of the adenomatous polyposis coli protein (APC) depends, in part, on its ability to bind and regulate the multifunctional…”
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The Role of Cadherin, β-Catenin, and AP-1 in Retinoid-regulated Carcinoma Cell Differentiation and Proliferation by Shah, Salimuddin, Pishvaian, Michael J., Easwaran, Vijayasurian, Brown, Powell H., Byers, Stephen W.

“…Vitamin A derivatives (retinoids) are potent regulators of cell proliferation and differentiation. Retinoids inhibit the function of the oncogenic AP-1 and…”
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The development of novel 1,2-dihydro-pyrimido[4,5- c]pyridazine based inhibitors of lymphocyte specific kinase (Lck) by Sabat, Mark, VanRens, John C., Brugel, Todd A., Maier, Jennifer, Laufersweiler, Matthew J., Golebiowski, Adam, De, Biswanath, Easwaran, Vijayasurian, Hsieh, Lily C., Rosegen, Jeff, Berberich, Steve, Suchanek, Eric, Janusz, Michael J.

“…This communication details the synthesis, biological activity, and proposed binding mode of a novel class of tri-cyclic derivatives of…”
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Development of N-4,6-pyrimidine- N-alkyl- N′-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase by Maier, Jennifer A., Brugel, Todd A., Sabat, Mark, Golebiowski, Adam, Laufersweiler, Matthew J., VanRens, John C., Hopkins, Corey R., De, Biswanath, Hsieh, Lily C., Brown, Kimberly K., Easwaran, Vijayasurian, Janusz, Michael J.

“…A new class of lymphocyte specific tyrosine kinase (lck) inhibitors based on an N-4,6-pyrimidine- N-alkyl- N′-phenyl urea scaffold is described. A new class of…”
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The Role of Cadherin, β-Catenin, and AP-1 in Retinoid-regulated Carcinoma Cell Differentiation and Proliferation by Salimuddin Shah, Michael J. Pishvaian, Vijayasurian Easwaran, Powell H. Brown, Stephen W. Byers

“…Vitamin A derivatives (retinoids) are potent regulators of cell proliferation and differentiation. Retinoids inhibit the function of the oncogenic AP-1 and…”
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The Ubiquitin-Proteasome Pathway and Serine Kinase Activity Modulate Adenomatous Polyposis Coli Protein-mediated Regulation of β-Catenin-Lymphocyte Enhancer-binding Factor Signaling by Vijayasurian Easwaran, Virginia Song, Paul Polakis, Stephen Byers

“…The tumor suppressor function of the adenomatous polyposis coli protein (APC) depends, in part, on its ability to bind and regulate the multifunctional…”
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Regulation of beta-catenin/LEF signaling in cancer cells by Easwaran, Vijayasurian

“…β-catenin is a multifunctional protein that participates in cadherin-mediated cell-cell adhesion and in transduction of the Wnt growth factor signal that…”
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