Search Results - "Vijayakumar, Sudhamathi"
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Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development
Published in PLoS neglected tropical diseases (26-06-2015)“…In this study, a Burkholderia mallei tonB mutant (TMM001) deficient in iron acquisition was constructed, characterized, and evaluated for its protective…”
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Prophylactic application of CpG oligonucleotides augments the early host response and confers protection in acute melioidosis
Published in PloS one (20-03-2012)“…Prophylactic administration of CpG oligodeoxynucleotides (CpG ODNs) is known to confer protection against lethal sepsis caused by Burkholderia pseudomallei in…”
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Monitoring Therapeutic Treatments against Burkholderia Infections Using Imaging Techniques
Published in Pathogens (Basel) (01-06-2013)“…, the etiologic agent of glanders, are Category B select agents with biothreat potential, and yet effective therapeutic treatments are lacking. In this study,…”
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Pulmonary Tuberculosis in Humanized Mice Infected with HIV-1
Published in Scientific reports (24-02-2016)“…Co-infection with HIV increases the morbidity and mortality associated with tuberculosis due to multiple factors including a poorly understood microbial…”
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A small animal model of immune reconstitution inflammatory syndrome following antiretroviral therapy (CAM1P.159)
Published in The Journal of immunology (1950) (01-05-2015)“…In HIV-infected patients with latent or subclinical tuberculosis (TB), the development of immune reconstitution inflammatory syndrome (IRIS) following…”
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Comparative Burkholderia pseudomallei natural history virulence studies using an aerosol murine model of infection
Published in Scientific reports (07-03-2014)“…Melioidosis is an endemic disease caused by the bacterium Burkholderia pseudomallei . Concerns exist regarding B. pseudomallei use as a potential bio-threat…”
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Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development: e0003863
Published in PLoS neglected tropical diseases (01-06-2015)“…Background In this study, a Burkholderia mallei tonB mutant (TMM001) deficient in iron acquisition was constructed, characterized, and evaluated for its…”
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HIV-1 promotes neutrophil infiltration and lung damage in humanized mice co-infected with Mycobacterium tuberculosis (HUM1P.266)
Published in The Journal of immunology (1950) (01-05-2015)“…Co-infection with human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) promotes aggressive disease through mechanisms that are poorly…”
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In vitro model of mycobacteria and HIV-1 co-infection for drug discovery
Published in Tuberculosis (Edinburgh, Scotland) (01-12-2013)“…Tuberculosis (TB) has become a global health threat in the wake of the Human Immunodeficiency Virus (HIV) pandemic and is the leading cause of death in people…”
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