Search Results - "Vijaya Padma, Viswanadha"

Berbamine ameliorates isoproterenol‐induced myocardial infarction by inhibiting mitochondrial dysfunction and apoptosis in rats by Saranya, Sithuraj, Baskaran, Rathinasamy, Poornima, Paramasivan, Vijaya Padma, Viswanadha

“…Berbamine (BBM), a bisbenzylisoquinoline alkaloid from roots, bark, and stem of Berberis plant such as Berberis aristata has a wide range of pharmacological…”
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Isoliensinine augments the therapeutic potential of paclitaxel in multidrug‐resistant colon cancer stem cells and induced mitochondria‐mediated cell death by Manogaran, Prasath, Anandan, Aparna, Vijaya Padma, Viswanadha

“…Previously we have reported the isoliensinine (ISO) potentates the therapeutic potential of cisplatin in cisplatin resistant colorectal cancer stem cells. The…”
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Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis by Hsu, Hsi‐Hsien, Chen, Ming‐Cheng, Baskaran, Rathinasamy, Lin, Yueh‐Min, Day, Cecilia H., Lin, Yi‐Jiun, Tu, Chuan‐Chou, Vijaya Padma, Viswanadha, Kuo, Wei‐Wen, Huang, Chih‐Yang

“…Oxaliplatin (OXA), is a third generation platinum drug used as first‐line chemotherapy in colorectal cancer (CRC). Cancer cells acquires resistance to…”
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Neferine modulates IGF‐1R/Nrf2 signaling in doxorubicin treated H9c2 cardiomyoblasts by Bharathi Priya, Lohanathan, Baskaran, Rathinasamy, Huang, Chih‐Yang, Vijaya Padma, Viswanadha

“…Doxorubicin (DOX) induced cardiotoxicity is a major problem during chemotherapy of cancers. DOX‐mediated suppression of type 1 IGF receptor (IGF‐1R) signaling…”
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Organometallic ruthenium(II) complexes: Synthesis, structure and influence of substitution at azomethine carbon towards DNA/BSA binding, radical scavenging and cytotoxicity by Sathyadevi, Palanisamy, Krishnamoorthy, Paramasivam, Bhuvanesh, Nattamai S.P., Kalaiselvi, Palaniswamy, Vijaya Padma, Viswanadha, Dharmaraj, Nallasamy

“…Bivalent, ruthenium organometallics containing hydrazone ligands with the composition [RuH(CO)(PPh3)2(L1−3)] (4–6) have been synthesised from the reactions of…”
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Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co(III) complexes of 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde thiosemicarbazones by Ramachandran, Eswaran, Thomas, Sajesh P., Poornima, Paramasivan, Kalaivani, Palaniappan, Prabhakaran, Rathinasabapathi, Padma, Viswanadha Vijaya, Natarajan, Karuppannan

“…Four new 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde N-substituted thiosemicarbazone ligands (H2-LR, where R = H, Me, Et or Ph) and their corresponding…”
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Bioactive Peptide VHVV Upregulates the Long-Term Memory-Related Biomarkers in Adult Spontaneously Hypertensive Rats by Ju, Da-Tong, K, Ashok Kumar, Kuo, Wei-Wen, Ho, Tsung-Jung, Chang, Ruey-Lin, Lin, Wan-Teng, Day, Cecilia Hsuan, Viswanadha, V Vijaya Padma, Liao, Po-Hsiang, Huang, Chih-Yang

“…Hypertension is one of the growing risk factors for the progression of long-term memory loss. Hypertension-mediated memory loss and treatment remain not…”
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Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice by Dumeus, Stanley, Shibu, Marthandam Asokan, Lin, Wan-Teng, Wang, Ming-Fu, Lai, Chao-Hung, Shen, Chia-Yao, Lin, Yueh-Min, Viswanadha, Vijaya Padma, Kuo, Wei-Wen, Huang, Chih-Yang

“…Abstract Background/Aims: High-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) poses therapeutic challenges in elderly subjects. Due to lack of…”
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Anti-Apoptotic and Pro-Survival Effect of Alpinate Oxyphyllae Fructus (AOF) in a d-Galactose-Induced Aging Heart by Chang, Yung-Ming, Chang, Hen-Hong, Kuo, Wei-Wen, Lin, Hung-Jen, Yeh, Yu-Lan, Padma Viswanadha, Vijaya, Tsai, Chin-Chuan, Chen, Ray-Jade, Chang, Hsin-Nung, Huang, Chih-Yang

“…Aging, a natural biological/physiological phenomenon, is accelerated by reactive oxygen species (ROS) accumulation and identified by a progressive decrease in…”
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Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice by Hu, Wei-Syun, Rajendran, Peramaiyan, Tzang, Bor-Show, Yeh, Yu-Lan, Shen, Chia-Yao, Chen, Ray-Jade, Ho, Tsung-Jung, Vijaya Padma, Viswanadha, Chen, Yi-Hsing, Huang, Chih-Yang

“…Systemic lupus erythematosus (SLE) is a disease that mostly affects women. Accelerated atherosclerosis is a high-risk factor associated with SLE patients. SLE…”
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Short‐Term Hypoxia Reverses Ox‐LDL‐Induced CD36 and GLUT4 Switching Metabolic Pathways in H9c2 Cardiomyoblast Cells by Chen, Yeh‐Peng, Hsu, Hsi‐Hsien, Baskaran, Rathinasamy, Wen, Su‐Ying, Shen, Chia‐Yao, Day, Cecilia‐Hsuan, Ho, Tsung‐Jung, Vijaya Padma, Viswanadha, Kuo, Wei‐Wen, Huang, Chih‐Yang

“…ABSTRACT High levels of circulating low‐density lipoproteins (LDL, plasma proteins that carry cholesterol and triglycerides) are associated with type 2…”
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Effect of quercetin against lindane induced alterations in the serum and hepatic tissue lipids in wistar rats by Padma, Viswanadha Vijaya, Lalitha, Gurusamy, Shirony, Nicholson Puthanveedu, Baskaran, Rathinasamy

“…Objective:To assess the effect of quercetin(flavonoid) against lindane induced alterations in lipid profile of wistar rats.Methods:Rats were administered…”
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Reversal of cisplatin resistance by neferine/isoliensinine and their combinatorial regimens with cisplatin‐induced apoptosis in cisplatin‐resistant colon cancer stem cells (CSCs) by Manogaran, Prasath, Somasundaram, Bharath, Viswanadha, Vijaya Padma

“…Cisplatin chemotherapy to the colorectal cancer cells (CRCs) is accompanied by dose‐limiting adverse effects along with the acquisition of drug resistance…”
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Ochratoxin-induced toxicity, oxidative stress and apoptosis ameliorated by quercetin – Modulation by Nrf2 by Ramyaa, Periasamy, Padma, Viswanadha Vijaya

“…•Quercetin protects Vero cells from OTA induced cytotoxicity.•OTA-induced toxicity was mediated by increased oxidative stress.•Quercetin exerts its…”
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Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells by Poornima, Paramasivan, Weng, Ching Feng, Padma, Viswanadha Vijaya

“…•We examine the antiproliferative effect of neferine on lung cancer cells.•Neferine exerts cytotoxicity in a dose dependent manner.•ROS hypergeneration and GSH…”
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Induction of Apoptosis by Ginger in HEp‐2 Cell Line Is Mediated by Reactive Oxygen Species by Vijaya Padma, Viswanadha, Arul Diana Christie, Swamidurai, Ramkuma, Kunga Mohan

“…:   Ginger (Zingiber officinale Roscoe, Zingiberaceae) is a commonly used medicinal herb throughout the world. Although some studies have demonstrated its…”
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Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade by Priya, Lohanathan Bharathi, Baskaran, Rathinasamy, Huang, Chih-Yang, Padma, Viswanadha Vijaya

“…Doxorubicin (DOX) mediated cardiomyopathy is a major challenge in cancer chemotherapy. Redox-cycling of doxorubicin by flavoenzymes makes the heart more…”
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Neferine augments therapeutic efficacy of cisplatin through ROS- mediated non-canonical autophagy in human lung adenocarcinoma (A549 cells) by Kalai Selvi, Sivalingam, Vinoth, Amirthalingam, Varadharajan, Thiyagarajan, Weng, Ching Feng, Vijaya Padma, Viswanadha

“…Combination of dietary components with chemotherapy drugs is an emerging new strategy for cancer therapy to increase antitumor responses. Neferine, major…”
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Neferine and isoliensinine enhance ‘intracellular uptake of cisplatin’ and induce ‘ROS-mediated apoptosis’ in colorectal cancer cells – A comparative study by Manogaran, Prasath, Beeraka, Narasimha Murthy, Huang, Chih-Yang, Vijaya Padma, Viswanadha

“…Cisplatin (CDDP) is a potent platinum-based chemotherapeutic agent used to treat solid tumors including colorectal cancer via inducing cytotoxicity. CDDP usage…”
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The Cytoprotective and Anti-cancer Potential of Bisbenzylisoquinoline Alkaloids from Nelumbo nucifera by Manogaran, Prasath, Beeraka, Narasimha Murthy, Padma, Viswanadha Vijaya

“…Natural product therapy has been gaining therapeutic importance against various diseases, including cancer. The failure of chemotherapy due to its associated…”
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