Search Results - "Vijay, K."
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Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
Published in Immunity (Cambridge, Mass.) (17-05-2016)“…Co-inhibitory receptors, such as CTLA-4 and PD-1, have an important role in regulating T cell responses and have proven to be effective targets in the setting…”
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Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
Published in Immunity (Cambridge, Mass.) (15-12-2015)“…The T helper 17 (Th17) cell pathway has been linked by genome-wide association studies to multiple autoimmune diseases. Identification of the genetic causes of…”
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Tim‐3 and its role in regulating anti‐tumor immunity
Published in Immunological reviews (01-03-2017)“…Summary Immunotherapy is being increasingly recognized as a key therapeutic modality to treat cancer and represents one of the most exciting treatments for the…”
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TIM3 comes of age as an inhibitory receptor
Published in Nature reviews. Immunology (01-03-2020)“…T cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a member of the TIM family, was originally identified as a receptor expressed on…”
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State-of-the-art review of morphological advancements in graphitic carbon nitride (g-CN) for sustainable hydrogen production
Published in Renewable & sustainable energy reviews (01-01-2021)“…Considering the technological benefits, the generation of hydrogen (H2) via solar-powered enabled water splitting is not only an ideal route to harvest and…”
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A Survey on Non-Orthogonal Multiple Access for 5G Networks: Research Challenges and Future Trends
Published in IEEE journal on selected areas in communications (01-10-2017)“…Non-orthogonal multiple access (NOMA) is an essential enabling technology for the fifth-generation (5G) wireless networks to meet the heterogeneous demands on…”
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Tim-3: A co-receptor with diverse roles in T cell exhaustion and tolerance
Published in Seminars in immunology (01-04-2019)“…T cell inhibitory co-receptors play a crucial role in maintaining the balance between physiologic immune responses and maladaptive ones. T cell immunoglobulin…”
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Interleukin-17 and Type 17 Helper T Cells
Published in The New England journal of medicine (27-08-2009)“…Type 17 helper T cells (Th17) — a third class of T cells — and their major cytokine, interleukin-17, are essential for the defense against certain fungi,…”
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Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
Published in Immunity (Cambridge, Mass.) (17-04-2014)“…Foxp3+ T regulatory (Treg) cells regulate immune responses and maintain self-tolerance. Recent work shows that Treg cells are comprised of many subpopulations…”
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A longitudinal study on the mental health of general population during the COVID-19 epidemic in China
Published in Brain, behavior, and immunity (01-07-2020)“…•A significant reduction in psychological impact 4 weeks after COVID outbreak.•The mean scores of respondents in both surveys were above PTSD cut-offs.•Female…”
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Joint Downlink Cell Association and Bandwidth Allocation for Wireless Backhauling in Two-Tier HetNets With Large-Scale Antenna Arrays
Published in IEEE transactions on wireless communications (01-05-2016)“…The problem of joint downlink cell association (CA) and wireless backhaul bandwidth allocation (WBBA) in two-tier cellular heterogeneous networks (HetNets) is…”
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The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
Published in Cell research (01-04-2020)“…Co-inhibitory receptors are important regulators of T-cell function that define the balance between tolerance and autoimmunity. The immune regulatory function…”
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A facile nanocasting synthesis of mesoporous Ag-doped SnO2 nanostructures with enhanced humidity sensing performance
Published in Sensors and actuators. B, Chemical (01-02-2016)“…•Mesoporous Ag/SnO2 based sensor was synthesized using nanocasting strategy.•Mesoporous SnO2 shows 7.5-fold higher sensitivity than conventional SnO2.•Ag/SnO2…”
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TH17 cell heterogeneity and its role in tissue inflammation
Published in Nature immunology (2023)“…Since their discovery almost two decades ago, interleukin-17-producing CD4 + T cells (T H 17 cells) have been implicated in the pathogenesis of multiple…”
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Estimation of root zone soil moisture from ground and remotely sensed soil information with multisensor data fusion and automated machine learning
Published in Remote sensing of environment (01-07-2021)“…Root zone soil moisture (RZSM) estimation and monitoring based on high spatial resolution remote sensing information such as obtained with an Unmanned Aerial…”
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Computational targeting of allosteric site of MEK1 by quinoline‐based molecules
Published in Cell biochemistry and function (01-07-2022)“…MEK1 is an attractive target due to its role in selective extracellular‐signal‐regulated kinase phosphorylation, which plays a pivotal role in regulating cell…”
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A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures
Published in International journal of radiation biology (02-09-2017)“…Purpose: The increasing global risk of nuclear and radiological accidents or attacks has driven renewed research interest in developing medical countermeasures…”
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Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming
Published in Cancer cell (10-06-2013)“…Gene expression profiling has uncovered the transcription factor Sox4 with upregulated activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in…”
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Current status of pesticide effects on environment, human health and it’s eco-friendly management as bioremediation: A comprehensive review
Published in Frontiers in microbiology (17-08-2022)“…Pesticides are either natural or chemically synthesized compounds that are used to control a variety of pests. These chemical compounds are used in a variety…”
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T H -17 cells in the circle of immunity and autoimmunity
Published in Nature immunology (01-04-2007)Get full text
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