Search Results - "Viil, Janeli"

Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability by Midekessa, Getnet, Godakumara, Kasun, Ord, James, Viil, Janeli, Lättekivi, Freddy, Dissanayake, Keerthie, Kopanchuk, Sergei, Rinken, Ago, Andronowska, Aneta, Bhattacharjee, Sourav, Rinken, Toonika, Fazeli, Alireza

“…Extracellular vesicles (EVs), including exosomes and microvesicles (<200 nm), play a vital role in intercellular communication and carry a net negative surface…”
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The alterations in the extracellular matrix composition guide the repair of damaged liver tissue by Klaas, Mariliis, Kangur, Triin, Viil, Janeli, Mäemets-Allas, Kristina, Minajeva, Ave, Vadi, Krista, Antsov, Mikk, Lapidus, Natalia, Järvekülg, Martin, Jaks, Viljar

“…While the cellular mechanisms of liver regeneration have been thoroughly studied, the role of extracellular matrix (ECM) in liver regeneration is still poorly…”
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Characterization of IMG Microglial Cell Line as a Valuable In Vitro Tool for NLRP3 Inflammasome Studies by Viil, Janeli, Somelar-Duracz, Kelli, Jaako, Külli, Anier, Kaili, Zharkovsky, Alexander

“…Microglial cells constantly surveil the cerebral microenvironment and become activated following injury and disease to mediate inflammatory responses. The…”
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Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue by Dissanayake, Keerthie, Nõmm, Monika, Lättekivi, Freddy, Ord, James, Ressaissi, Yosra, Godakumara, Kasun, Reshi, Qurat Ul Ain, Viil, Janeli, Jääger, Kersti, Velthut-Meikas, Agne, Salumets, Andres, Jaakma, Ülle, Fazeli, Alireza

“…Embryo-derived extracellular vesicles (EVs) may play a role in mediating the embryo-maternal dialogue at the oviduct, potentially carrying signals reflecting…”
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Cellular, Extracellular and Extracellular Vesicular miRNA Profiles of Pre-Ovulatory Follicles Indicate Signaling Disturbances in Polycystic Ovaries by Rooda, Ilmatar, Hasan, Mohammad Mehedi, Roos, Kristine, Viil, Janeli, Andronowska, Aneta, Smolander, Olli-Pekka, Jaakma, Ülle, Salumets, Andres, Fazeli, Alireza, Velthut-Meikas, Agne

“…Cell-free RNAs have the potential to act as a means of gene expression regulation between cells and are therefore used as diagnostic markers describing the…”
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Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication by Godakumara, Kasun, Ord, James, Lättekivi, Freddy, Dissanayake, Keerthie, Viil, Janeli, Boggavarapu, Nageswara Rao, Faridani, Omid R, Jääger, Kersti, Velthut-Meikas, Agne, Jaakma, Ülle, Salumets, Andres, Fazeli, Alireza

“…The period of time when the embryo and the endometrium undergo significant morphological alterations to facilitate a successful implantation-known as "window…”
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Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome by Hasan, Mohammad Mehedi, Viil, Janeli, Lättekivi, Freddy, Ord, James, Reshi, Qurat Ul Ain, Jääger, Kersti, Velthut-Meikas, Agne, Andronowska, Aneta, Jaakma, Ülle, Salumets, Andres, Fazeli, Alireza

“…While follicular fluid (FF) is well known to provide an optimal environment for oogenesis, its functional roles following its release into the oviduct during…”
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Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk by Es-Haghi, Masoumeh, Godakumara, Kasun, Häling, Annika, Lättekivi, Freddy, Lavrits, Arina, Viil, Janeli, Andronowska, Aneta, Nafee, Tamer, James, Victoria, Jaakma, Ülle, Salumets, Andres, Fazeli, Alireza

“…Successful establishment of pregnancy hinges on appropriate communication between the embryo and the uterus prior to implantation, but the nature of this…”
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Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers by Lättekivi, Freddy, Guljavina, Irina, Midekessa, Getnet, Viil, Janeli, Heath, Paul R, Bæk, Rikke, Jørgensen, Malene Møller, Andronowska, Aneta, Kingo, Kulli, Fazeli, Alireza

“…Psoriasis vulgaris (PsV) and psoriatic arthritis (PsA) are inflammatory diseases with unresolved pathophysiological aspects. Extracellular vesicles (EVs) play…”
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Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa by Hasan, Mohammad Mehedi, Reshi, Qurat Ul Ain, Lättekivi, Freddy, Viil, Janeli, Godakumara, Kasun, Dissanayake, Keerthie, Andronowska, Aneta, Jaakma, Ülle, Fazeli, Alireza

“…While follicular fluid (FF) is known to enhance the functional properties of spermatozoa, the role of FF-derived extracellular vesicles (EVs) in this respect…”
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Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact by Reshi, Qurat Ul Ain, Viil, Janeli, Ord, James, Lättekivi, Freddy, Godakumara, Kasun, Hasan, Mohammad Mehedi, Nõmm, Monika, Jääger, Kersti, Velthut-Meikas, Agne, Jaakma, Ülle, Salumets, Andres, Fazeli, Alireza

“…The capability of spermatozoa to directly influence maternal gene expression is already established. Indeed, some of the changes induced by spermatozoa may…”
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Enzyme-assisted extraction of anthocyanins and other phenolic compounds from blackcurrant (Ribes nigrum L.) press cake: From processing to bioactivities by Granato, Daniel, Fidelis, Marina, Haapakoski, Marjo, dos Santos Lima, Amanda, Viil, Janeli, Hellström, Jarkko, Rätsep, Reelika, Kaldmäe, Hedi, Bleive, Uko, Azevedo, Luciana, Marjomäki, Varpu, Zharkovsky, Alexander, Pap, Nora

“…[Display omitted] •Blackcurrant press cake (BPC) was extracted with cellulase/beta-glucanase/pectinase.•Enzyme-assisted extraction increased the recovery to…”
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Unpredictable chronic mild stress does not exacerbate memory impairment or altered neuronal and glial plasticity in the hippocampus of middle‐aged vitamin D deficient mice by Somelar‐Duracz, Kelli, Jürgenson, Monika, Viil, Janeli, Zharkovsky, Alexander, Jaako, Külli

“…Vitamin D deficiency is a worldwide health concern, especially in the elderly population. Much remains unknown about the relationship between vitamin D…”
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Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers by Dissanayake, Keerthie, Nõmm, Monika, Lättekivi, Freddy, Ressaissi, Yosra, Godakumara, Kasun, Lavrits, Arina, Midekessa, Getnet, Viil, Janeli, Bæk, Rikke, Jørgensen, Malene Møller, Bhattacharjee, Sourav, Andronowska, Aneta, Salumets, Andres, Jaakma, Ülle, Fazeli, Alireza

“…Extracellular vesicles (EVs) are membrane-bound biological nanoparticles (NPs) and have gained wide attention as potential biomarkers. We aimed to isolate and…”
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Endogenous beta‐galactosidase activity marks a TREM2‐expressing Kupffer cell population in injured livers of Lgr5‐LacZ and wild‐type mice by Klaas, Mariliis, Mäemets‐Allas, Kristina, Lõhmussaar, Kadi, Tooming, Mikk, Viil, Janeli, Jaks, Viljar

“…Lgr5‐LacZ mice harbor the Escherichia coli LacZ gene encoding β‐galactosidase (β‐gal) under the control of the Lgr5 promoter, a stem/progenitor cell marker. In…”
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A Novel Inhibitor of AKT1-PDPK1 Interaction Efficiently Suppresses the Activity of AKT Pathway and Restricts Tumor Growth In Vivo by Mäemets-Allas, Kristina, Viil, Janeli, Jaks, Viljar

“…The serine/threonine kinase AKT/PKB has a critical role in the regulation of cell proliferation. Because AKT signaling is deregulated in numerous human…”
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Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis by Urgard, Egon, Lorents, Annely, Klaas, Mariliis, Padari, Kärt, Viil, Janeli, Runnel, Toomas, Langel, Kent, Kingo, Külli, Tkaczyk, Eric, Langel, Ülo, Maimets, Toivo, Jaks, Viljar, Pooga, Margus, Rebane, Ana

“…The skin is a difficult to access tissue for efficient delivery of large and/or charged macromolecules, including therapeutic DNA and RNA oligonucleotides…”
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A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver by Viil, Janeli, Klaas, Mariliis, Valter, Kadri, Belitškin, Denis, Ilmjärv, Sten, Jaks, Viljar

“…Cells with slow proliferation kinetics that retain the nuclear label over long time periods–the label-retaining cells (LRCs)–represent multipotent stem cells…”
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Leukocyte marker CD43 promotes cell growth in co-operation with β-catenin in non-hematopoietic cancer cells by BALIKOVA, Anna, JÄÄGER, Kersti, VILL, Janeli, MAIMETS, Toivo, KADAJA-SAAREPUU, Lilian

“…The Wnt/β-catenin pathway regulates key cellular processes such as differentiation, proliferation, apoptosis; and its activation promotes development of…”
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Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren's contracture by Viil, Janeli, Maasalu, Katre, Mäemets-Allas, Kristina, Tamming, Liis, Lõhmussaar, Kadi, Tooming, Mikk, Ingerpuu, Sulev, Märtson, Aare, Jaks, Viljar

“…Dupuytren's contracture (DC) is a chronic fibroproliferative disease of the hand, which is characterized by uncontrolled proliferation of atypical…”
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